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Added in Afterbirth
Karma Icon.png
Item Type
Item ID
Pickup Quote
Karma up
Unlock Method
Karma Afterbirth-exclusive content Defeat The Lamb as Keeper

Karma is a trinket added in The Binding of Isaac: Afterbirth expansion.

Effect[edit | edit source]

  • Donating to a Donation Machine has a chance to heal Isaac for a full red heart or spawn a Beggar.
  • Increases the chance that donating to a Donation Machine will increase Isaac's luck.

Notes[edit | edit source]

  • There is a bug where this trinket can be obtained through a Fortune Teller machine even if it is not unlocked yet.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • The Symbol is a Triskelion, also known as a Triskele, which is often used to represent karma.

SmallIsaac.png The Binding of Isaac: Rebirth SmallIsaac.png

MainPageAchievements.png Achievements MainPageAttributes.png Attributes MainPageBosses.png Bosses TarotCard.png Cards and Runes MainPageChallenges.png Challenges MainPageChapters.png Chapters
Isaac App.png Characters MainPageBabies.png Co-op Magic Mushroom Icon.png Items Isaac's Tears Icon.png Item Pools MainPageMonsters.png Monsters MainPageObjects.png Objects
Red heart.png Pickups BlueBlue.png Pills MainPageRooms.png Rooms MainPageSeeds2.png Seeds Guppy App.png Transformations The Left Hand Icon.png Trinkets