Major changes are coming to the Wiki! To learn more and let your voice be heard, please go here.

Additionally, we are currently experiencing some bugs and glitches. We're working on fixing them, but please be aware this means certain images, such as the collection grid for items, will be replaced by errors for the time being.

Leprosy

From Binding of Isaac: Rebirth Wiki
Jump to: navigation, search
Font TeamMeat L.pngFont TeamMeat e.pngFont TeamMeat p.pngFont TeamMeat r.pngFont TeamMeat o.pngFont TeamMeat s.pngFont TeamMeat y.png
Item icon
Item altar
 
 
 
Table dividing line 1.png
 
 
Character appearance
Table dividing line 2.png
 
Treasure Room Treasure Room
Table dividing line 3.png
 
(page 5, column 18, row 2)
(page Expression error: Unexpected < operator., column Expression error: Unexpected < operator., row Expression error: Unexpected < operator.)
 
Leprosy Beat Chapter 3 without taking damageLeprosyLeprosy
Added in Afterbirth †

Leprosy is an unlockable passive item added in Booster Pack #2.

Effects[edit | edit source]

  • Upon taking damage, Isaac gains a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with.
    • A maximum of three body parts can be active at once.
    • The body parts will be destroyed if they take enough damage from enemies or enemy shots.
    • The body parts persist between floors.
    • Body parts orbit on the same layer as Blue Flies and Locusts do.

Synergies[edit | edit source]

  • Dull Razor Dull RazorDull Razor Icon.png2 roomsHurts Isaac without depleting health, activating any items that trigger upon taking damage.: Allows Isaac to spawn orbitals without reducing health.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Leprosy is based on this Steam Workshop item by Extreme Ninja Home Makeover.
    • Originally, this item added a chance to shoot limbs instead of tears which increased Isaac's movement speed.
  • The pickup quote is a reference to Rebel Wilson’s well known line “You’re tearing me apart!”.
    • It could also be argued that the quote is referencing The Room's infamous line "You are tearing me apart Lisa!"
  • The item is a reference to the disease leprosy; one of its notable symptoms is the loss of extremities.
  • The item used to be misspelled Leprocy, but was corrected in a later patch.
  • Its appearance is changed slightly for The Forgotten due to his lack of skin, making him look like Melting from the game Nuclear Throne.

Gallery[edit | edit source]


Moving Box Icon.png Booster Packs Moving Box Icon.png
#1
  • Angry FlyAngry FlySpawns a fly familiar that orbits around a random enemy and deals 5 damage per tick to enemies it comes in contact with.
  • Black HoleBlack HoleThrows a black hole on the ground which sucks in and damages enemies.
  • BozoBozoIncreases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.
  • Broken ModemBroken ModemEnemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals.
  • Mystery GiftMystery GiftUpon use, spawns a random item from the current room's item pool, with a chance to spawn A Lump of Coal or The Poop instead.
  • SprinklerSprinklerUpon use, spawns a sprinkler that rotates and fires tears.
  • Fast BombsFast BombsGrants 7 bombs and allows bombs to be placed rapidly.
  • Buddy in a BoxBuddy in a BoxGrants a familiar with a random tear effect. The familiar is randomized at the start of each floor.
  • Lil DeliriumLil DeliriumGrants a familiar that transforms into another random familiar every 10 seconds.
  • HairpinHairpinFully recharges Isaac's active item upon entering a boss fight.
  • Wooden CrossWooden CrossGrants a Holy Mantle shield upon entering a new floor, which protects against one hit of damage.
  • Butter!Butter!Using an active item will drop it onto a pedestal on the ground. Taking damage may result in dropping a passive item.
  • Huge GrowthHuge GrowthMakes Isaac large for the current room, increasing his range and damage.
  • Ancient RecallAncient RecallSpawns 3 random cards.
  • Era WalkEra WalkFor the current room, enemies are slowed, Isaac's speed is increased, and his shot speed is decreased.
#2
  • Jumper CablesJumper CablesGrants an active item charge every 15 enemies killed.
  • CouponCouponUpon use, makes a random item from a shop, devil deal, or black market free.
  • TelekinesisTelekinesisUpon use, for the next two seconds, any enemy shots that come near Isaac are held in place. After the charge is depleted, they are fired back as tears.
  • Moving BoxMoving BoxIf the box is empty, picks up all items and pickups in a room and stores them. If the box is not empty, places all stored items and pickups in the current room.
  • Technology ZeroTechnology ZeroConnects Isaac's tears with electricity that can damage enemies.
  • LeprosyLeprosyUpon taking damage, grants a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with. The orbitals will be destroyed if they take enough damage from enemies or enemy shots.
  • Filigree FeatherFiligree FeatherAngels drop items instead of key pieces when defeated.
  • Dressing Table.png
#3
  • 7 Seals7 SealsGrants a random Harbinger familiar that changes every 10 seconds.
  • Mr. ME!Mr. ME!Summons a controllable ghost that can perform various tasks depending on what it targets.
  • Angelic PrismAngelic PrismGrants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
  • Pop!Pop!Replaces Isaac's tears with eyeballs that can bounce off of each other. The eyeballs are not limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle.
  • Door StopDoor StopThe last door Isaac went through stays open, allowing him to leave the room even if enemies are in it.
#4
  • Death's ListDeath's ListGrants a reward if all enemies in a room are killed in the order they are marked.
  • HaemolacriaHaemolacriaTears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay.
  • LachryphagyLachryphagyIsaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage.
  • TrisagionTrisagionTears are replaced with piercing white blasts of light.
  • SchoolbagSchoolbagAllows Isaac to hold two active items.
  • Extension CordExtension CordBeams of yellow electricity flow between Isaac and his familiars, damaging any enemies between them.
  • Cross Grimace.png
  • Fistuloid.png
  • Gush.png
  • Soul Sucker.png
  • Tar Boy.png
  • Tube Worm.png
#5
  • BlanketBlanketGrants one soul heart. Upon entering a boss room, grants a shield that blocks one hit, then disappears.
  • Sacrificial AltarSacrificial AltarUpon use, sacrifices up to 2 familiars and spawns an item from the Devil Room Pool for each familiar sacrificed.
  • Lil SpewerLil SpewerSpawns a random pill, and grants a small Spewer familiar that charges up and fires different types of creep.
  • MarblesMarblesSpawns 3 random trinkets. Taking damage has a small chance to swallow Isaac's currently held trinket, gaining its effect permanently.
  • Mystery EggMystery EggSpawns an egg familiar, which cracks and turns into a random charmed enemy when Isaac is hurt. The egg regenerates upon entering a different room.
  • Flat StoneFlat StoneTears bounce off the floor. Tears that hit an enemy after bouncing deal splash damage to all nearby enemies for 25% of Isaac's tear damage.
  • MarrowMarrowGrants one bone heart and spawns three red heart pickups.
  • Slipped RibSlipped RibSpawns a bone familiar that circles around Isaac and reflects enemy shots.
  • Hallowed GroundHallowed GroundSpawns a white poop familiar, which turns into a white poop when Isaac is hurt.
  • Pointy RibPointy RibSpawns a bone familiar that can be aimed with the fire buttons and does contact damage.
  • Book of the DeadBook of the DeadUpon use, spawns a charmed Bony or an orbital bone for each enemy killed in the current room.
  • Dad's RingDad's RingCreates a ring of light around Isaac that petrifies enemies in contact.
  • Divorce PapersDivorce PapersSpawns a Mysterious Paper, increases tears, and grants a bone heart.
  • Jaw BoneJaw BoneSpawns a familiar that flies the room while firing, dealing double Isaac's tear damage to enemies that come in contact and retrieving pickups.
  • Brittle BonesBrittle BonesReplaces all red hearts with 6 empty bone hearts. Upon losing a bone heart, Isaac fires bones in 8 directions and permanently gains a tears up.
  • Broken ShovelBroken ShovelWhile held, causes multiple Mom's Foots to come down and stomp on Isaac. One of two parts necessary to create Mom's Shovel.
  • Broken ShovelBroken ShovelOne of two parts necessary to create Mom's Shovel.
  • Mom's ShovelMom's ShovelSpawns a trapdoor that leads to the next floor upon activation. Unlocks The Forgotten when used on a mound of dirt that appears in The Dark Room.
  • Rotten PennyRotten PennySpawns a blue fly every time a coin is picked up.
  • Baby-BenderBaby-BenderGrants Isaac's familiars homing shots.
  • Finger BoneFinger BoneGrants a chance to gain a bone heart upon taking damage.
  • The Forgotten App.png
  • Crispy.png
  • Cross Stoney.png
  • Dank Charger.png
  • Leper.png
  • Mr. Mine.png
  • Mr. Red Maw.png
  • Boss The Matriarch.png
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item Pools Item Pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets