Leprosy

5.100.525

Treasure Room Treasure Room

(page 5, column 20, row 2)

Beat chapter 3 without taking damage

Leprosy is an unlockable passive item added in Booster Pack #2.

Effects

• Upon taking damage, Isaac gains a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with.
  • A maximum of three body parts can be active at once.
  • The body parts will be destroyed after dealing 30 ticks of damage and/or blocking 3 shots.
  • The body parts persist between floors.
  • Body parts orbit on the same layer as Blue Flies and Locusts do.

Interactions

• Box of Friends: Will not multiply orbitals.

Trivia

• Leprosy was inspired by this Steam Workshop item by Bobby Lashley Fangirl #1.
• The item used to be misspelled "Leprocy" but was corrected in a later patch.
• Its appearance is changed slightly for The Forgotten due to his lack of skin, making him look like Melting from the game Nuclear Throne.
• The item is a reference to Leprosy, a bacterial disease that damages nerves and can cause extremities to rot in extreme cases.

Gallery

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Booster Packs
#1
#2
#3
#4
#5