Leprosy

5.100.525

Treasure Room Treasure Room

(page 5, column 20, row 2)

Beat chapter 3 without taking damageLeprosy

Leprosy is an unlockable passive item added in Booster Pack #2.

Effects

• Upon taking damage, Isaac gains a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with.
  • A maximum of three body parts can be active at once.
  • The body parts will be destroyed if they take enough damage from enemies or enemy shots.
  • The body parts persist between floors.
  • Body parts orbit on the same layer as Blue Flies and Locusts do.

Interactions

• Box of Friends: Will not multiply orbitals.

Trivia

• Leprosy was inspired by this Steam Workshop item by Bobby Lashley Fangirl #1.
• The item used to be misspelled "Leprocy" but was corrected in a later patch.
• Its appearance is changed slightly for The Forgotten due to his lack of skin, making him look like Melting from the game Nuclear Throne.
• The item is a reference to Leprosy, a bacterial disease that damages nerves and can cause extremities to rot in extreme cases.

Gallery

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Booster Packs
#1	HairpinFully recharges Isaac's active item upon entering a boss fight. Wooden CrossGrants a Holy Mantle shield upon entering a new floor, which protects against one hit of damage. Butter!Using an active item will drop it onto a pedestal on the ground. Taking damage may result in dropping a passive item. Huge GrowthMakes Isaac large for the current room, increasing his range and damage. Ancient RecallSpawns 3 random cards. Era WalkFor the current room, enemies are slowed, Isaac's speed is increased, and his shot speed is decreased.
#2	Filigree FeatherAngels drop items instead of key pieces when defeated.
#3	Door StopThe last door Isaac went through stays open, allowing him to leave the room even if enemies are in it.
#4	Extension CordBeams of yellow electricity flow between Isaac and his familiars, damaging any enemies between them.
#5	Rotten PennySpawns a blue fly every time a coin is picked up. Baby-BenderGrants Isaac's familiars homing shots. Finger BoneGrants a chance to gain a bone heart upon taking damage.