Locust of Pestilence

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Locust of Pestilence Defeat Satan as Apollyon
Added in Afterbirth †

Locust of Pestilence is an unlockable trinket added in The Binding of Isaac: Afterbirth † expansion.

Effects[edit | edit source]

  • Upon entering a room with enemies, spawns a Green Locust that deals double Isaac's damage and poisons enemies, which deals double Isaac's damage over time.

Notes[edit | edit source]

  • The Locust will also spawn each time a wave in Boss Rush starts.
  • During Greed Mode, locusts will not spawn when waves start.

In-game Footage[edit | edit source]


Apollyon Unlocks Apollyon Unlocks Apollyon Unlocks
VoidBlack RuneLocust of WrathLocust of PestilenceLocust of FamineLocust of DeathLocust of ConquestHushyBrown NuggetMort BabySmelterApollyon Baby
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