Locust of Pestilence

Defeat Satan as ApollyonLocust of Pestilence

Locust of Pestilence is an unlockable trinket added in The Binding of Isaac: Afterbirth † expansion.

Effects

• Upon entering a room with enemies, spawns a Green Locust that deals double Isaac's damage and poisons enemies, which deals double Isaac's damage over time.

Notes

• The Locust will also spawn each time a wave in Boss Rush starts.
• During Greed Mode, locusts will not spawn when waves start.

In-game Footage

Locusts

• Locust of ConquestUpon entering a room with enemies, spawns 2-5 White Locusts which damage enemies.
• Locust of DeathUpon entering a room with enemies, spawns a Black Locust that does a very high amount of damage.
• Locust of FamineUpon entering a room with enemies, spawns a Yellow Locust that damages and slows enemies.
• Locust of PestilenceUpon entering a room with enemies, spawns a Green Locust which damages and poisons enemies.
• Locust of WarUpon entering a room with enemies, spawns a Red Locust which detonates upon impact with enemies.

Apollyon Unlocks
VoidDefeat Delirium as ApollyonBlack RuneDefeat Ultra Greedier as ApollyonLocust of WrathDefeat Isaac as ApollyonLocust of PestilenceDefeat Satan as ApollyonLocust of FamineDefeat ??? as ApollyonLocust of DeathDefeat The Lamb as ApollyonLocust of ConquestComplete the Boss Rush as ApollyonHushyDefeat Hush as ApollyonBrown NuggetDefeat Ultra Greed as ApollyonMort BabyDefeat Mega Satan as ApollyonSmelterDefeat Mom's Heart or It Lives! on hard mode as ApollyonApollyon BabyEarn all hard mode completion marks as Apollyon