Magdalene's biggest disadvantage is her low speed, which makes her more vulnerable to threats, especially from fast-moving attacks and homing projectiles. Look to get items that increase speed and avoid those that lower it further.
Once the Aprils Foolchallenge is completed, this disadvantage is rendered moot as she will start every run with a Speed Up pill.
Abaddon removes all red heart containers, which can turn out to be a disadvantage for Magdalene.
Bucket of Lard's heart container bonus is tempting, though it's better to avoid this item initially as it would render Magdalene's speed very low. Any other speed down items are to be avoided as well (Taurus may make an exception from its speed increase over time and My Little Unicorn effect if the speed becomes high enough).
Dark Bum eats red heart pickups, which can dampen Magdalene's regenerative play style. However, used in conjunction with her starting Yum Heart, Dark Bum can be a powerful way to turn otherwise redundant pickups to your advantage.
If Dead Cat is picked up early, it takes away Magdalene's primary strength (high health) and exacerbates her biggest weakness (low avoidance).
Maggy's unlock requirements in Rebirth are the same in the original Binding of Isaac.
Magdalene is a reference to Mary Magdalene, a follower of Jesus who had seven demons cast out of her body, referenced with the seven heart containers needed to unlock her. She has been canonized as a saint in several Christian denominations and is believed to have been a prostitute before following Jesus (though this has no textual basis in the Bible, and is considered by scholars to be a baseless myth).
In the game files, the image file for Maggy's hair is named maggiesbeautifulgoldenlocks.png.
Maggy's hair appears to be identical to the wig that Isaac receives in one of his mid-floor nightmares. It may be possible that the character of Maggy might be Isaac wearing a wig.
The person with gold hair in ending 14 and the Final ending has been confirmed to be Isaac wearing a wig, which furthers this idea.
Another piece of evidence is that the three female playable characters all have Isaac's voice.
This page was last edited on 20 December 2020, at 18:03.
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