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Item icon
Item altar
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2 rooms 2  rooms
Treasure Room Treasure Room
Greed mode only Shop Shop
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(page 5, column 3, row 1)
Metronome Defeat Ultra Greedier as EdenMetronomeMetronome
Added in Afterbirth †

Metronome is an unlockable activated item added in Afterbirth †.

Effect[edit | edit source]

  • Grants a random item's effect for the current room.

Notes[edit | edit source]

  • Beware using this as The Lost, as it can trigger self-harm items and kill him.
  • Using this item multiple times in the same room will replace the previous item with a new one.
  • Metronome cannot grant the effects of itself,Glowing Hour Glass Glowing Hour GlassCollectible Glowing Hour Glass icon.png2 roomsWhen used, this item will rewind time, put Isaac back in the previous room, and undo anything that happened in the current room. Any health, pickups, or items gained or lost will be reset back to the previous state. orPlan C Plan CCollectible Plan C icon.pngOne time useKills all enemies in the room, then kills Isaac three seconds later..

Interactions[edit | edit source]

  • Car Battery Car BatteryCollectible Car Battery icon.pngCauses Isaac's activated item to activate twice on each use.: Metronome is activated twice at once as expected, but the item chosen for the first activation is shown raised above Isaac's head, instead of the second one that actually remains active.

Specific Item Effects[edit | edit source]

  • Certain items used by Metronome have permanent, limited/unusual or no effect. It is not clear what is intended and what is a bug.
  • Permanent effects include:
    • Health, coins, bombs, or keys that are granted to Isaac directly will persist.
    • Clicker ClickerCollectible Clicker icon.png6 roomsTransforms Isaac into another random character. will permanently remove the latest item and change character.
    • Cube of Meat Cube of MeatCollectible Cube of Meat icon.pngOrbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages. granted byPotato Peeler Potato PeelerCollectible Potato Peeler icon.pngUnlimitedRemoves a heart container, increases damage and range, and grants a Cube of Meat. will persist.
    • D8 D8Collectible D8 icon.png4 roomsRe-rolls Isaac's speed, range, tears, and damage.'s rerolled stat multipliers will persist, D4 D4Collectible D4 icon.png6 roomsRerolls all of Isaac's items. or D100 D100Collectible D100 icon.png6 roomsUpon use, rerolls all passive items on Isaac like the D4, every pedestal item in the room like The D6, and every pickup like the D20. will reroll all items permamently andD Infinity D InfinityCollectible D Infinity icon.png2 roomsGrants a random dice item that changes each use. mimicking any of the previous also has the same effects.
    • Dataminer DataminerCollectible Dataminer icon.png4 roomsDisplaces enemy sprites for the current room, randomly increases one stat and decreases another.'s stat changes will persist.
    • Forget Me Now Forget Me NowCollectible Forget Me Now icon.pngOne time useWhen activated, the level ends and is freshly regenerated with new rooms, monsters, and items. Disappears after use. will restart the level.
    • Void VoidCollectible Void icon.png6 roomsConsumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant stat upgrades. absorbing passives and granting stats will persist.
  • Limited and unusual effects include:
    • Items do not spawn pickups and consumables that they might when picked up normally.
    • Items that adjust Isaac's size will not do so.
    • 1up! 1up!1up! icon.pngGives an extra life. Upon death, you will respawn in the previous room with full health and lose the 1up!. and Guppy's Collar Guppy's CollarCollectible Guppy's Collar icon.pngGrants Isaac a permanent 50% chance to respawn with 1/2 of a red heart after death. give no indication of extra lives, but will still work if you die in the room.
    • Abaddon AbaddonCollectible Abaddon Rebirth icon.pngIncreases damage and speed, removes all red heart containers, grants six black hearts, and adds a chance to shoot fear tears. will not remove red hearts or grant black hearts.
    • Belly Button Belly ButtonCollectible Belly Button icon.pngDrops a random trinket. Grants a second trinket slot. and Mom's Purse Mom's PurseCollectible Mom's Purse icon.pngAllows Isaac to hold 1 additional trinket. allow picking up two trinkets in the room, but if another one is picked up outside, one trinket disappears completely along the extra slot.
    • Black Candle Black CandleCollectible Black Candle icon.pngPrevents curses. Grants one black heart. Increases the chance for a Devil or angel room to appear. only adds a black heart and does not remove curses.
    • Brittle Bones Brittle BonesCollectible Brittle Bones icon.pngReplaces all red hearts with 6 empty bone hearts. Upon losing a bone heart, Isaac fires bones in 8 directions and permanently gains a tears up. andDivorce Papers Divorce PapersCollectible Divorce Papers icon.pngSpawns a Mysterious Paper, increases tears, and grants a bone heart. do not grant bone hearts. Brittle Bones can still be used to gain permanent tears ups if bone hearts are available.
    • Crown of Light Crown of LightCollectible Crown of Light Afterbirth icon.pngGives Isaac a crown that glows blue when active, and turns gray when inactive. While Isaac has no empty red heart containers, Isaac's tears are replaced with blue diamond tears that deal double damage. Regardless of health, the crown will deactivate for the current room when Isaac takes damage. only adds soul hearts, no damage multiplier.
    • Dead Cat Dead CatCollectible Dead Cat icon.pngSets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room. New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again. will only restore one red heart without setting heart containers to 1. It also gives no extra lives.
    • Deep Pockets Deep PocketsCollectible Deep Pockets icon.pngAllows Isaac to carry two cards or pills (or a combination of both) at the same time., Little Baggy Little BaggyCollectible Little Baggy icon.pngIsaac can hold 2 pills at once and all cards are replaced by pills.,Polydactyly PolydactylyCollectible Polydactyly icon.pngAllows Isaac to carry two cards, pills, or any combination of both at the same time. Drops a random card or pill. and Starter Deck Starter DeckStarter Deck Icon.pngIsaac can hold 2 cards at once and all pills are replaced by cards. allow picking up two consumables while in the room and kept outside, but using them will lose the extra slot.
    • Eden's Blessing Eden's BlessingCollectible Eden's Blessing icon.png+0.7 tears up. Grants a random item at the start of the next run. will not grant an extra item for the next run.
    • Fate FateCollectible Fate icon.pngGrants flight and one eternal heart. only grants flight, no eternal heart.
    • PHD PHDCollectible PHD icon.pngConverts all bad pills into good pills, spawns one pill pickup and restores health. Identifies all pills upon pickup. will not identify pills, but they are still guaranteed to not be negative.
    • Schoolbag SchoolbagCollectible Schoolbag icon.pngAllows Isaac to hold two active items. allows picking up two activated items while in the room and they can be kept even outside, but the extra slot and one of the items is lost if another activated item is picked up.
  • The following items have no effect:
    • Items that only spawn pickups or consumables are not mentioned separately.
    • 3 Dollar Bill 3 Dollar Bill3 Dollar Bill Icon.pngGives Isaac a random tear effect every room.
      Removed in Afterbirth The effect given changes upon entering a room.
      Added in Afterbirth The effect changes every 3 seconds.
      , Ankh AnkhCollectible Ankh icon.pngUpon death, the player will respawn as ??? with 3 soul hearts., Blue Map Blue MapCollectible Blue Map icon.pngShows secret and super secret room locations on the map., Breath of Life Breath of LifeCollectible Breath of Life icon.png6 secondsGrants a brief moment of invincibility when the charge bar hits zero. If spacebar is held for an additional second after hitting zero, Isaac will take damage., Broken Watch Broken WatchCollectible Broken Watch icon.pngChance upon entering a room to slow down or speed up every enemy and their attacks. The chance to slow enemies is quite higher than the chance to speed them up.,Camo Undies Camo UndiesCollectible Camo Undies icon.pngIsaac becomes camouflaged at the beginning of each room. Enemies will not attack Isaac until he starts firing tears., The Candle The CandleThe Candle Icon.png4 secondsThrows out a blue flame that can pass over gaps (but not through rocks). The flame damages anything in its path., The Compass The CompassThe Compass Rebirth Icon.pngReveals all special rooms (except secret rooms of any kind).,Contagion ContagionCollectible Contagion icon.pngThe first enemy killed in a room explodes and poisons nearby enemies. Poisoned enemies will also explode upon death.,Death's List Death's ListCollectible Death's List icon.pngGrants a reward if all enemies in a room are killed in the order they are marked., Experimental Treatment Experimental TreatmentCollectible Experimental Treatment icon.pngRandomly increases and decreases some of the character's stats., Holy Mantle Holy MantleCollectible Holy Mantle icon.pngAutomatically negates first taken damage in every room., The Jar The JarCollectible The Jar Rebirth icon.pngUnlimitedWhen at full health, up to 4 extra hearts can be stored in the jar., Judas' Shadow Judas' ShadowCollectible Judas' Shadow icon.pngAdds an extra life; upon death, it respawns Isaac as Black Judas with only two black hearts., Lazarus' Rags Lazarus' RagsCollectible Lazarus' Rags icon.pngUpon dying, resurrect as Revived Lazarus with one heart container and Anemic item.,Marrow MarrowCollectible Marrow icon.pngGrants one bone heart and spawns three red heart pickups., The Mind The MindCollectible The Mind icon.pngGrants the combined effects of the Blue Map, Treasure Map, and The Compass, revealing the floor layout and all special rooms, including Secret Rooms and Super Secret Rooms., Missing No. Missing No.Collectible Missing No. icon.pngRandomizes all passive items upon pickup and at the start of each succeeding floor.,More Options More OptionsCollectible More Options icon.pngTwo items spawn in every Treasure Room. Only one can be taken; the other will disappear.,Poke Go Poke GoCollectible Poke Go icon.pngUpon entering a room with enemies in it, has a chance to spawn a random friendly enemy that persists across rooms.,Purity PurityCollectible Purity icon.pngThis item will boost one of Isaac's stats depending on the color of the aura around him. The aura will disappear upon taking damage and will reappear with a random color upon entering a new room. A red aura boosts damage, a blue aura boosts rate of fire, a yellow aura boosts speed, and an orange aura boosts range., Red Candle Red CandleCollectible Red Candle icon.png4 secondsThrows a persistent flame that deals high damage and diminishes as it damages enemies or blocks shots., Spelunker Hat Spelunker HatSpelunker Hat Icon.pngReveals type of adjacent rooms, including location for secret rooms and super secret rooms., Treasure Map Treasure MapCollectible Treasure Map icon.pngReveals all rooms for every floor. However, it does not reveal icons or secret rooms.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • The name, pickup quote, and effect of this item are a reference to the move 'Metronome' from the Pokémon franchise.
  • This item works similarly to the item Dead Sea Scrolls Dead Sea ScrollsCollectible Dead Sea Scrolls icon.png2 roomsTriggers the effect of a random activated item from a list of possible options (not every activated item is included)..

Eden Unlocks Eden Unlocks Eden Unlocks
Blank CardBlank CardDefeat Isaac as EdenBook of SecretsBook of SecretsDefeat Satan as EdenMysterious PaperMysterious PaperBeat ??? as EdenMystery SackMystery SackDefeat The Lamb as EdenUndefinedUndefinedComplete the Boss Rush as EdenGlitch BabyGlitch BabyDefeat Mom's Heart on hard mode as Eden Eden's BlessingEden's BlessingDefeat Hush as EdenGB BugGB BugDefeat Ultra Greed as EdenYellow BabyYellow BabyDefeat Mega Satan as EdenCracked BabyCracked BabyEarn all hard mode completion marks as Eden Eden's SoulEden's SoulDefeat Delirium as EdenMetronomeMetronomeDefeat Ultra Greedier as Eden
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
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