Missing No.

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Font TeamMeat M.pngFont TeamMeat i.pngFont TeamMeat s.pngFont TeamMeat s.pngFont TeamMeat i.pngFont TeamMeat n.pngFont TeamMeat g.png   Font TeamMeat N.pngFont TeamMeat o.pngFont TeamMeat point.png
Item icon
Item altar
 
Table dividing line 1.png
 
258
 
Character appearance
Table dividing line 2.png
 
Secret Room Secret Room
Greed mode only Treasure Room Treasure Room
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Added in  Afterbirth(page 3, column 14, row 1)
Removed in Afterbirth(page 3, column 4, row 6)
 
Missing No. Complete the Boss Rush as LazarusMissing No.Missing No.

Missing No. is an unlockable passive item.

Effects[edit | edit source]

  • Randomizes passive items and stats on pickup and at the start of every floor.
    • Stats gain a random flat modifier. These modifiers do not stack between levels and are instead rerolled every time.
      • Speed and maximum speed -0.2, 0 or +0.2. Maximum speed may never exceed 2.0.
      • Range -0.5, 0 or +0.5.
      • Tears -0.5, 0 or +0.5.
      • Shot speed -0.2, 0 or +0.2.
      • Damage -1, 0 or +1.
      • Luck -1, 0 or +1.
    • Does not affect trinkets, cards, pills, pretty flies, The Polaroid The PolaroidThe Polaroid Icon.pngIf the character has half a red heart or no red hearts after taking damage, it triggers the Book Of Shadows effect, creating a shield that nullifies all types of damage for 5 seconds. Also allows entrance into The Chest. / The Negative The NegativeThe Negative Icon.pngIf the character has half a red heart or no red hearts after taking damage, it triggers The Necronomicon effect, damaging all enemies in the room. Also allows entrance into the Dark Room., Key Pieces, or active items.
    • Can cause but does not remove transformations.
    • Missing No. cannot be re-rolled with D4 D4D4 Icon.png6 roomsRerolls all of Isaac's items. or D100 D100D100 Icon.png6 roomsUpon use, rerolls all passive items on Isaac like the D4, every pedestal item in the room like The D6, and every pickup like the D20. after being picked up.

In-game Footage[edit | edit source]

Strategy[edit | edit source]

  • There is no real strategy to Missing No. as it randomizes all the player's items. The benefit of the randomization can be added by collecting more items to increase the chance of a good item synergy.
  • However, this item can be used to gain more health if desperately needed, as the randomization does often include items that grant you various types of hearts.
  • If the player has already obtained a large number of items (such as during a run where they have gained infinite money in greed mode), it is highly recommended to avoid this item, as it will almost always end up rerolling all the items the player has thus far collected into Breakfast BreakfastBreakfast Icon.pngGrants Isaac one full red heart container..
  • Due to losing all items every level, it is beneficial to try to gain permanent stat boosts if possible. These include using pills when equipped with PHD PHDPHD Icon.pngConverts all bad pills into good pills, spawns one pill pickup and restores health. Identifies all pills upon pickup. or Virgo VirgoVirgo Icon.pngGrants a chance to trigger the Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 10 seconds. Also converts "bad pills" into "good pills"., sacrificing health with Added in Afterbirth †Potato Peeler Potato PeelerPotato Peeler Icon.pngUnlimitedRemoves a heart container, increases damage and range, and grants a Cube of Meat. to gain damage or Added in Afterbirth †Brittle Bones Brittle BonesBrittle Bones Icon.pngReplaces all red hearts with 6 empty bone hearts. Upon losing a bone heart, Isaac fires bones in 8 directions and permanently gains a tears up. to gain tears, or using up Judas' Shadow Judas' ShadowJudas' Shadow Icon.pngAdds an extra life; upon death, it respawns Isaac as Black Judas with only two black hearts..

Trivia[edit | edit source]

  • This item is a reference to the infamous Missing No. glitch occuring in the first Pokémon games. The glitch would often corrupt save files, and therefore randomize various parts of the game as it would use the incomplete index values attributed to entities not included in the final release of the game. Isaac's appearance when affected by Missing No. is based on this glitch which could cause the player's sprite to become scrambled.
  • The item also resembles the painting "Composition with Red, Yellow, and Blue" by Dutch painter Piet Mondrian.
  • The background color for the Missing No. achievement has the same color as all the challenge unlocks. This implies that Missing No. was originally intended to be unlocked via a challenge. (Or, perhaps, it was intended to be looked at as an error.)

Seeds[edit | edit source]

 PS4   PC  FTTQ E3RZ - Secret room directly to the right of the starting room

 PS4  X1F3 19X9 - First floor secret room to the left of the shop

 PC  2QDT ALD2 - First floor secret room to the bottom of the treasure room

 PC  W4Q7 JMMP - First floor secret room directly under the treasure room


Lazarus  Unlocks Lazarus Unlocks Lazarus  Unlocks
Added in  Afterbirth Added in Afterbirth †
Missing No.Missing No.Complete the Boss Rush as LazarusLazarus' RagsLazarus' RagsDefeat Isaac as LazarusBroken AnkhBroken AnkhDefeat Satan as LazarusStore CreditStore CreditDefeat ??? as LazarusPandora's BoxPandora's BoxDefeat The Lamb as LazarusWrapped BabyWrapped BabyRemoved in Afterbirth † Defeat Mom's Heart on hard mode as Azazel
Added in Afterbirth † Defeat Mom's Heart on hard mode as Lazarus
Begotten BabyBegotten BabyRemoved in Afterbirth † Defeat Mom's Heart on hard mode as Lazarus
Added in Afterbirth † Defeat Mom's Heart on hard mode as Azazel
Empty VesselEmpty VesselDefeat Hush as LazarusKey BumKey BumDefeat Ultra Greed as LazarusLong BabyLong BabyDefeat Mega Satan as LazarusDripping BabyDripping BabyEarn all hard mode completion marks as Lazarus Compound FractureCompound FractureDefeat Delirium as LazarusPlan CPlan CDefeat Ultra Greedier as Lazarus
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
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Characters Characters MainPageBabies.png Co-op Items Items Item Pools Item Pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets