Mr. ME!

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Item icon
Item altar
 
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527
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4  rooms 4  rooms
 
Shop Shop
Greed mode only Shop Shop
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(page 5, column 2, row 3)
 
Mr. ME! Open 20 locked chestsMr. ME!Mr. ME!
Added in Afterbirth †

Mr. ME! is an unlockable activated item added in Booster Pack #3.

Effects[edit | edit source]

  • Summons a ghost near Isaac that will follow him around, and summons a controllable blue crosshair. After a few seconds, the crosshair disappears, and the ghost will perform an action depending on what the crosshair was targeting:
    • Items, pickups, trinkets, brown/red/spiked chests: Brings it to Isaac. Works in shops, devil deals and black markets as well, making them effectively free. Stealing an item has a chance to fail. If that happens a buzzer sound will play out and the ghost will disappear without doing anything.
    • Golden/eternal/stone chests: Opens the chest for free.
    • Buttons: Presses the button.
    • Enemies: Attacks the enemy until it dies or becomes untargetable due to a form change or similar.
    • Doors: Opens the door, even if it is locked. Functions the same as Dad's Key when being used in this way. This includes the door to Mega Satan, exiting Hush's room, and exiting Boss Rush.
    • Secret room entrances: Explodes, opening the entrance.
    • Destructible obstacles, shopkeepers, machines, and beggars: Explodes and destroys them.

Notes[edit | edit source]

  • When used to attack, Mr. ME! deals 3 damage per tick at a slow rate, for 9 damage per second. BFFS! BFFS!BFFS! Icon.pngIncreases the size and damage of familiars. does not increase the damage.
  • Stealing an item from a shop will restock it with another item. This happens even if Isaac does not haveRestock RestockRestock Icon.pngCauses shops to instantly restock their items when they are bought. Granted by default for every character in Greed Mode..
    • Stealing from a black market will not restock items, as they work like devil deals.
  • If the crosshair is not targeting anything when the crosshair disappears, the ghost will interact with the object closest to the crosshair.
  • If the room has nothing to interact with, the ghost will disappear without doing anything.
  • The ghost cannot pick up sticky nickels, and will disappear upon touching them.
  • The ghost can press the button in Greed Mode, allowing waves to be stopped without taking damage.
  • The ghost can open chests in Challenge Rooms without triggering the room.
  • In rooms with multiple pedestal items where only one can be taken, if the ghost is carrying a pedestal while Isaac picks up a different pedestal item, the ghost will disappear. This prevents taking both items for free.
  • When used against Isaac (Boss) or ??? (Boss), the ghost will still try to chase the boss even when he flies away.

In-game Footage[edit | edit source]

Bugs[edit | edit source]

Bug Bug! The game crashes if Mr. ME! is used on the trophy at the end of a challenge.
Bug Bug! If the Devil Room or Angel Room disappears after leaving it, using Mr. ME! will still attempt to unlock the doorway back to it. This allows you to move through the wall as if there were a door there, but you will not be able to enter the Devil Room or Angel Room.

Trivia[edit | edit source]

  • Mr. ME! is based on this Steam Workshop item by Jean-Alphonse, originally known as Mr. Meeseeks.
  • Mr. ME! is a reference to Mr. Meeseeks from Rick and Morty, which spawn from a box and stop existing after completing their given task.
    • The pickup quote also refers to a catchphrase used by Mr. Meeseeks.

Gallery[edit | edit source]


Moving Box Icon.png Booster Packs Moving Box Icon.png
#1
  • Angry Fly Icon.png
    Angry Fly
    Spawns a fly familiar that orbits around a random enemy and deals 5 damage per tick to enemies it comes in contact with.
  • Black Hole Icon.png
    Black Hole
    Throws a black hole on the ground which sucks in and damages enemies.
  • Bozo Icon.png
    Bozo
    Increases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.
  • Broken Modem Icon.png
    Broken Modem
    Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals.
  • Mystery Gift Icon.png
    Mystery Gift
    Upon use, spawns a random item from the current room's item pool, with a chance to spawn A Lump of Coal or The Poop instead.
  • Sprinkler Icon.png
    Sprinkler
    Upon use, spawns a sprinkler that rotates and fires tears.
  • Fast Bombs Icon.png
    Fast Bombs
    Grants 7 bombs and allows bombs to be placed rapidly.
  • Buddy in a Box Icon.png
    Buddy in a Box
    Grants a familiar with a random tear effect. The familiar is randomized at the start of each floor.
  • Lil Delirium Icon.png
    Lil Delirium
    Grants a familiar that transforms into another random familiar every 10 seconds.
  • HairpinHairpinFully recharges Isaac's active item upon entering a boss fight.
  • Wooden CrossWooden CrossGrants a Holy Mantle shield upon entering a new floor, which protects against one hit of damage.
  • Butter!Butter!Using an active item will drop it onto a pedestal on the ground. Taking damage may result in dropping a passive item.
  • Huge GrowthHuge GrowthMakes Isaac large for the current room, increasing his range and damage.
  • Ancient RecallAncient RecallSpawns 3 random cards.
  • Era WalkEra WalkFor the current room, enemies are slowed, Isaac's speed is increased, and his shot speed is decreased.
#2
  • Jumper Cables Icon.png
    Jumper Cables
    Grants an active item charge every 15 enemies killed.
  • Coupon Icon.png
    Coupon
    Upon use, makes a random item from a shop, devil deal, or black market free.
  • Telekinesis Icon.png
    Telekinesis
    Upon use, for the next two seconds, any enemy shots that come near Isaac are held in place. After the charge is depleted, they are fired back as tears.
  • Moving Box Icon.png
    Moving Box
    If the box is empty, picks up all items and pickups in a room and stores them. If the box is not empty, places all stored items and pickups in the current room.
  • Technology Zero Icon.png
    Technology Zero
    Connects Isaac's tears with electricity that can damage enemies.
  • Leprosy Icon.png
    Leprosy
    Upon taking damage, grants a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with. The orbitals will be destroyed if they take enough damage from enemies or enemy shots.
  • Filigree FeatherFiligree FeatherAngels drop items instead of key pieces when defeated.
  • Dressing Table.png
#3
  • 7 Seals Icon.png
    7 Seals
    Grants a random Harbinger familiar that changes every 10 seconds.
  • Mr. ME! Icon.png
    Mr. ME!
    Summons a controllable ghost that can perform various tasks depending on what it targets.
  • Angelic Prism Icon.png
    Angelic Prism
    Grants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
  • Pop! Icon.png
    Pop!
    Replaces Isaac's tears with eyeballs that can bounce off of each other. The eyeballs are not limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle.
  • Door StopDoor StopThe last door Isaac went through stays open, allowing him to leave the room even if enemies are in it.
#4
  • Death's List Icon.png
    Death's List
    Grants a reward if all enemies in a room are killed in the order they are marked.
  • Haemolacria Icon.png
    Haemolacria
    Tears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay.
  • Lachryphagy Icon.png
    Lachryphagy
    Isaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage.
  • Trisagion Icon.png
    Trisagion
    Tears are replaced with piercing white blasts of light.
  • Schoolbag Icon.png
    Schoolbag
    Allows Isaac to hold two active items.
  • Extension CordExtension CordBeams of yellow electricity flow between Isaac and his familiars, damaging any enemies between them.
  • Cross Grimace.png
  • Fistuloid.png
  • Gush.png
  • Soul Sucker.png
  • Tar Boy.png
  • Tube Worm.png
#5
  • Blanket Icon.png
    Blanket
    Grants one soul heart. Upon entering a boss room, grants a shield that blocks one hit, then disappears.
  • Sacrificial Altar Icon.png
    Sacrificial Altar
    Upon use, sacrifices up to 2 familiars and spawns an item from the Devil Room Pool for each familiar sacrificed.
  • Lil Spewer Icon.png
    Lil Spewer
    Spawns a random pill, and grants a small Spewer familiar that charges up and fires different types of creep.
  • Marbles Icon.png
    Marbles
    Spawns 3 random trinkets. Taking damage has a small chance to swallow Isaac's currently held trinket, gaining its effect permanently.
  • Mystery Egg Icon.png
    Mystery Egg
    Spawns an egg familiar, which cracks and turns into a random friendly enemy when Isaac is hurt. The egg regenerates upon entering a different room.
  • Flat Stone Icon.png
    Flat Stone
    Tears bounce off the floor. Tears that hit an enemy after bouncing deal splash damage to all nearby enemies for 25% of Isaac's tear damage.
  • Marrow Icon.png
    Marrow
    Grants one bone heart and spawns three red heart pickups.
  • Slipped Rib Icon.png
    Slipped Rib
    Spawns a bone familiar that circles around Isaac and reflects enemy shots.
  • Hallowed Ground Icon.png
    Hallowed Ground
    Spawns a white poop familiar, which turns into a white poop when Isaac is hurt.
  • Pointy Rib Icon.png
    Pointy Rib
    Spawns a bone familiar that can be aimed with the fire buttons and does contact damage.
  • Book of the Dead Icon.png
    Book of the Dead
    Upon use, spawns a friendly Bony or an orbital bone for each enemy killed in the current room.
  • Dad's Ring Icon.png
    Dad's Ring
    Creates a ring of light around Isaac that petrifies enemies in contact.
  • Divorce Papers Icon.png
    Divorce Papers
    Spawns a Mysterious Paper, increases tears, and grants a bone heart.
  • Jaw Bone Icon.png
    Jaw Bone
    Spawns a familiar that flies the room while firing, dealing a flat 7 damage to enemies that come in contact and retrieving pickups.
  • Brittle Bones Icon.png
    Brittle Bones
    Replaces all red hearts with 6 empty bone hearts. Upon losing a bone heart, Isaac fires bones in 8 directions and permanently gains a tears up.
  • Broken Shovel 1 Icon.png
    Broken Shovel
    While held, causes multiple Mom's Foots to come down and stomp on Isaac. One of two parts necessary to create Mom's Shovel.
  • Broken Shovel 2 Icon.png
    Broken Shovel
    One of two parts necessary to create Mom's Shovel.
  • Mom's Shovel Icon.png
    Mom's Shovel
    Spawns a trapdoor that leads to the next floor upon activation. Unlocks The Forgotten when used on a mound of dirt that appears in The Dark Room.
  • Rotten PennyRotten PennySpawns a blue fly every time a coin is picked up.
  • Baby-BenderBaby-BenderGrants Isaac's familiars homing shots.
  • Finger BoneFinger BoneGrants a chance to gain a bone heart upon taking damage.
  • The Forgotten App.png
  • Crispy.png
  • Cross Stoney.png
  • Dank Charger.png
  • Leper.png
  • Mr. Mine.png
  • Mr. Red Maw.png
  • Boss The Matriarch.png
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