Mutant Spider

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Item icon
Item altar

 
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Character appearance
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Item Pool Treasure Room.png Treasure Room
Added in AfterbirthGreed mode onlyItem Pool Treasure Room.png Treasure Room
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Added in Afterbirth (page 2, column 10, line 2)
Removed in Afterbirth (page 2, column 10, line 5)

Mutant Spider is a Special passive item.

Effect[edit | edit source]

  • Isaac fires a spread of four tears at once.
  • Tears down: (Delay * 2.1) + 3
  • Added in Afterbirth † This item belongs to the Spider Baby set. Collecting three items from this set will transform Isaac into a humanoid spider.

Interactions[edit | edit source]

  • Azazel: Fires four short ranged brimstone beams that overlap. Significant increase in tear delay.
  • Brimstone BrimstoneBrimstone Icon.pngTears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.: Isaac fires four lasers at once at the cost of a severely increased charge time.
  • Added in Afterbirth † The Forgotten: Quadruples bones thrown and swung. Significant increase in tear delay.
  • Ipecac IpecacIpecac Icon.pngReplaces tears with explosive and poisoning projectiles fired in an arc from the mouth.: Four projectiles are fired at once at a lower tear rate.
  • Added in Afterbirth Keeper: Shoots 7 tears at once with greatly decreased fire rate.
  • Loki's Horns Loki's HornsLoki's Horns Icon.pngGives a random chance for projectiles to fire in all 4 cardinal directions.: Only occasionally fires one tear in the other three directions.
  • Mom's Eye Mom's EyeMom's Eye Icon.pngAllows Isaac to fire tears from the back of his head.: Only occasionally fires one tear out of the back of Isaac's head.
  • Monstro's Lung Monstro's LungMonstro's Lung Icon.pngIncreases damage and grants a charged shot that fires multiple tears in the same fashion as Monstro.: Isaac fires many more tears at the cost of a severely increased charge time.
  • Added in AfterbirthThe Wiz The WizThe Wiz Icon.pngTears simultaneously fire out of both eyes diagonally, similar to the effect of the R U A Wizard? pill. Isaac's tears also travel above all obstacles.: Four shots are fired diagonally out of each eye.

Synergies[edit | edit source]

  • Added in Afterbirth 20/20 20/2020 20 Icon.pngGrants double shot.: Shoots 6 tears with no further decrease in fire rate.
  • Added in Afterbirth †Angelic Prism Angelic PrismAngelic Prism Icon.pngGrants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.: Tears that hit the prism will be quadrupled, resulting in a maximum of 16 tears.
  • Brimstone BrimstoneBrimstone Icon.pngTears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.: Grants a quadruple laser at the cost of increased charge time.
  • Added in Afterbirth †Compound Fracture Compound FractureCompound Fracture Icon.pngIncreases range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle./Cricket's Body Cricket's BodyCricket's Body Icon.pngGrants -1 Tear Delay and reduces Range. When tears hit an object or deplete their range, they spawn 4 smaller tears, whose Range and Damage scale with Isaac's./The Parasite The ParasiteThe Parasite Icon.pngIsaac's tears split in two when they hit something.: Fires four tears that all split into burst tears.
  • Cursed Eye Cursed EyeCursed Eye Icon.pngGrants charged tears that can be fired in a tight burst of four. Getting hit while charging will teleport Isaac into another room.: At full charge, fires 4 rows of 4 tears, resulting in 16 tears.
  • Added in AfterbirthDiplopia DiplopiaDiplopia Icon.pngOne time useDuplicates all pickups and item pedestals in the room.: Effects stack, results in 8 tears being shot with no decrease in fire rate.
  • Doctor's Remote Doctor's RemoteDoctor's Remote Icon.png2 roomsSets a big red target on the ground (similar to the Epic Fetus item) which can be controlled with tear controls. After 6 seconds or by pressing space again, a huge explosive missile hits it, which damages all enemies caught in its blast radius./Epic Fetus Epic FetusEpic Fetus Icon.pngIsaac's tears are replaced with guided missiles, like those used by the Doctor's Remote.: Replaces the single missile strike with a barrage of four consecutive missiles.
  • Dr. Fetus Dr. FetusDr. Fetus Icon.pngTears are replaced by bombs that benefit from bomb-enhancing effects and slide a fixed range after being fired.: Four bombs are fired at once.
  • Epic Fetus Epic FetusEpic Fetus Icon.pngIsaac's tears are replaced with guided missiles, like those used by the Doctor's Remote.: Replaces the single missile strike with a barrage of four consecutive missiles.
  • Added in Afterbirth The Inner Eye The Inner EyeThe Inner Eye Icon.pngGrants triple shot but decreases tears.: Shoots 7 tears with no decrease in fire rate.
  • Ipecac IpecacIpecac Icon.pngReplaces tears with explosive and poisoning projectiles fired in an arc from the mouth.: Fires four explosives with a significant increase in fire rate.
  • Added in AfterbirthKidney Stone Kidney StoneKidney Stone Icon.pngRandomly while firing tears, Isaac will stop firing and turn red, where he will charge and release a lot of 'tears' in one go. In the burst of tears is a kidney stone which deals a lot of damage.: Increase number of tears in tear barrage; however, only fires one stone.
  • The Ludovico Technique The Ludovico TechniqueThe Ludovico Technique Icon.pngInstead of firing tears, Isaac controls one floating tear that hover over obstacles. This tear deals constant damage when held in place over an enemy.: The Ludovico tear gains three orbiting tears.
  • Mom's Knife Mom's KnifeMom's Knife Icon.pngIsaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.: Isaac still holds one knife, but firing shoots four knives at once.
  • Polyphemus PolyphemusPolyphemus Icon.pngMakes Isaac shoot one huge tear. Also reduces Tears to minimum. Damage increased . If tear does more damage than an enemy's life, the tear continues to travel with the extra remaining damage.: Tear rate is not lowered further. Damage is increased by a flat +5 instead of normal Polyphemus boost.
  • Sacred Heart Sacred HeartSacred Heart Icon.pngIncreases damage and range while reducing shot speed and grants homing tears. Grants a Heart Container and replenishes all Red Hearts.: Causes all four tears to home on enemies and do massive damage.
  • Soy Milk Soy MilkSoy Milk Icon.pngTears shrink and do much less damage, but fire in very rapid succession.: Rapidly shoots four streams of tears.
  • Added in Afterbirth †Sprinkler SprinklerSprinkler Icon.png4 roomsUpon use, spawns a sprinkler that rotates and fires tears.: Fires 4 tears with increased tear delay.
  • Technology TechnologyTechnology Icon.pngReplaces tears with a piercing laser with unlimited range.: Isaac fires four lasers at once.
  • Added in AfterbirthTech X Tech XTech X Icon.pngTears are replaced with laser rings that pierce through enemies and deal damage to enemies within them. Can be charged to increase the size of the ring.: Fires four laser rings with decreased fire rate.
  • Technology 2 Technology 2Technology 2 Icon.pngDecreases damage and replaces right eye tears with a unlimited range, piercing laser which fires continuously.: Isaac can still fire four tears at once whilst gaining the laser, although with a lower fire rate.
  • Added in AfterbirthTractor Beam Tractor BeamTractor Beam Icon.pngIsaac emits a beam from his face. Isaac's tears travel in the path of the beam.: Fires 4 tears in a cluster along the tractor beam.
  • Added in Afterbirth †Trisagion TrisagionTrisagion Icon.pngTears are replaced with piercing white blasts of light.: Fires four beams that overlap with decreased fire rate.

In-game Footage[edit | edit source]

Seeds[edit | edit source]

 PC  AZ6W Y26Y (Treasure room adjacent to spawn)

 PC  TJXE 4V96 (Treasure room adjacent to spawn)

 PC  GFZN B8DP (First floor treasure room)

 PC Added in Afterbirth 007A C1TS (Treasure room adjacent to spawn)

 PC Added in Afterbirth BX4E YVR0 (Treasure room adjacent to spawn) (Both modes)

 PC Added in Afterbirth 46XR GGB4 (Treasure room adjacent to spawn)

 PS4  BPJS S7WT (Treasure room adjacent to spawn)

 PS4  GALT H2PG (Treasure room adjacent to spawn)

 Vita  S37R YZKY (First floor treasure room)

 3DS  MYNT 04LF (Treasure room adjacent to spawn)

 3DS  HW2X X7V4 (Treasure room adjacent to spawn)

 Switch  Greed mode only Y4SW L1YF (First Golden Treasure Room)

 Switch  Greedier mode only VSG9 BYPQ (First Golden Treasure Room)

 Switch  Added in Afterbirth 1B8Y 37ZS (Treasure room adjacent to spawn)

 Switch  Added in Afterbirth NDAV 7AY6 (Treasure room adjacent to spawn) Normal mode only


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