Mutant Spider

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Item icon
Item altar
Table dividing line 1.png


Character appearance
Table dividing line 2.png
Table dividing line 3.png

Added in Afterbirth(page 2, column 10, row 2)
Removed in Afterbirth(page 2, column 10, row 5)

Mutant Spider is a Special passive item.

Effect[edit | edit source]

  • Isaac fires a spread of four tears at once.
  • Tears down: (Delay * 2.1) + 3
  • Added in Afterbirth † This item belongs to the Spider Baby set. Collecting three items from this set will transform Isaac into a humanoid spider.

Synergies[edit | edit source]

  • Added in Afterbirth 20/20 20/20: Shoots 6 tears with no further decrease in fire rate.
  • Brimstone Brimstone: Grants a quadruple laser at the cost of increased charge time.
  • Added in AfterbirthDiplopia Diplopia: Effects stack, results in 8 tears being shot with no further decrease in fire rate.
  • Doctor's Remote Doctor's Remote/Epic Fetus Epic Fetus: Replaces the single missile strike with a barrage of four consecutive missiles.
  • Dr. Fetus Dr. Fetus: Four bombs are fired at once.
  • Added in Afterbirth The Inner Eye The Inner Eye: Shoots 7 tears with no further decrease in fire rate.
  • Added in AfterbirthKidney Stone Kidney Stone: Increase number of tears in tear barrage; however, only fires one stone.
  • The Ludovico Technique The Ludovico Technique: The tear gains three orbiting tears.
  • Mom's Knife Mom's Knife: Only one knife is still held, but four are fired in a spread.
  • Polyphemus Polyphemus: Tear rate is not lowered further. Damage is increased by a flat +5 instead of normal Polyphemus boost.
  • Technology 2 Technology 2 / Tech.5 Tech.5: The laser is not affected by Mutant Spider.
  • Added in AfterbirthTractor Beam Tractor Beam: The tears cluster up along the tractor beam making hitting all 4 shots on a single target easier.

Interactions[edit | edit source]

  • Added in Afterbirth † The Forgotten: Quadruples bones thrown and swung. Significant increase in tear delay.
  • Loki's Horns Loki's Horns: Only occasionally fires one tear in the other three directions.
  • Mom's Eye Mom's Eye: Only occasionally fires one tear out of the back of Isaac's head.
  • Added in AfterbirthThe Wiz The Wiz: Four shots are fired diagonally out of each eye.
    • Added in Afterbirth † Fires three shots diagonally out of each eye.

Notes[edit | edit source]

  • The maximum amount of tears per volley that can be reached by combining and/or duplicating 20/20 20/20, The Inner Eye The Inner Eye, Mutant Spider and Added in AfterbirthThe Wiz The Wiz is 16.

In-game Footage[edit | edit source]

Seeds[edit | edit source]

 PC  AZ6W Y26Y (Treasure room adjacent to spawn)

 PC  TJXE 4V96 (Treasure room adjacent to spawn)

 PC  GFZN B8DP (First floor treasure room)

 PC Added in Afterbirth 007A C1TS (Treasure room adjacent to spawn)

 PC Added in Afterbirth BX4E YVR0 (Treasure room adjacent to spawn) (Both modes)

 PC Added in Afterbirth 46XR GGB4 (Treasure room adjacent to spawn)

 PS4  BPJS S7WT (Treasure room adjacent to spawn)

 PS4  GALT H2PG (Treasure room adjacent to spawn)

 Vita  S37R YZKY (First floor treasure room)

 3DS  MYNT 04LF (Treasure room adjacent to spawn)

 3DS  HW2X X7V4 (Treasure room adjacent to spawn)

 Switch  Greed mode only Y4SW L1YF (First Golden Treasure Room)

 Switch  Greedier mode only VSG9 BYPQ (First Golden Treasure Room)

 Switch  Added in Afterbirth 1B8Y 37ZS (Treasure room adjacent to spawn)

 Switch  Added in Afterbirth NDAV 7AY6 (Treasure room adjacent to spawn) Normal mode only

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