Mysterious Liquid

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Font TeamMeat M.pngFont TeamMeat y.pngFont TeamMeat s.pngFont TeamMeat t.pngFont TeamMeat e.pngFont TeamMeat r.pngFont TeamMeat i.pngFont TeamMeat o.pngFont TeamMeat u.pngFont TeamMeat s.png   Font TeamMeat L.pngFont TeamMeat i.pngFont TeamMeat q.pngFont TeamMeat u.pngFont TeamMeat i.pngFont TeamMeat d.png
Item icon
Item altar
Table dividing line 1.png
Character appearance
Tear appearance
Table dividing line 2.png
Treasure Room Treasure Room
Greed mode only Treasure Room Treasure Room
Table dividing line 3.png
Added in Afterbirth(page 3, column 12, row 4)
Removed in Afterbirth(page 4, column 2, row 2)

Mysterious Liquid is a passive item.

Effect[edit | edit source]

  • Tears leave a small, short lasting pool of creep upon hitting an enemy or when their range is depleted.
    • The creep deals 1 damage per tick or 30 damage per second.

Synergies[edit | edit source]

  • Added in Afterbirth †Compound Fracture Compound FractureCollectible Compound Fracture icon.pngIncreases range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle./Cricket's Body Cricket's BodyCollectible Cricket's Body icon.pngGrants -1 Tear Delay and reduces Range. When tears hit an object or deplete their range, they spawn 4 smaller tears, whose Range and Damage scale with Isaac's./The Parasite The ParasiteCollectible The Parasite icon.pngIsaac's tears split in two when they hit something.: Each split tear leaves a pool of creep, creating lots of creep.
  • Added in AfterbirthExplosivo ExplosivoCollectible Explosivo icon.pngIsaac's tears have a chance to stick to enemies and explode.: Generates an explosion-sized pool of creep whenever explosivo tear goes off.
  • Added in Afterbirth †Flat Stone Flat StoneCollectible Flat Stone icon.pngTears bounce off the floor. Tears that hit an enemy after bouncing deal splash damage to all nearby enemies for 25% of Isaac's tear damage.: Every time tears bounce, creep spawns.
  • Mom's Knife Mom's KnifeCollectible Mom's Knife Rebirth icon.pngIsaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.: Creates a line of creep behind the knife as it shoots towards enemies.
  • Added in AfterbirthTech X Tech XTech X Icon.pngTears are replaced with laser rings that pierce through enemies and deal damage to enemies within them. Can be charged to increase the size of the ring.: The laser ring often spawns pools of liquid when it hits enemies.
  • Added in Afterbirth † Tech.5 Tech.5Tech.5 Rebirth Icon.pngGrants a unlimited range piercing laser with random rate of fire that does not replace tears. The laser might occasionally fire with the effect of a random item or trinket, such as Hook Worm, Spoon Bender or Tiny Planet.: The laser spawns pools of liquid always when it hits obstacles and occasionally on enemies.
  • Added in Afterbirth † Technology 2 Technology 2Technology 2 Icon.pngDecreases damage and replaces right eye tears with a unlimited range, piercing laser which fires continuously.: The laser rapidly spawns pools of liquid on hitting both obstacles and enemies.
  • Added in Afterbirth †Trisagion TrisagionCollectible Trisagion icon.pngTears are replaced with piercing white blasts of light.: Causes a large trail of creep. The effect stacks, which causes heavy damage (even to Hush).

Interactions[edit | edit source]

  • Brimstone BrimstoneCollectible Brimstone Rebirth icon.pngTears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.: Overrides Mysterious Liquid.
    • Added in Afterbirth The beam spawns pools of liquid always when it hits obstacles and often on enemies.
      • Azazel: Pools of liquid are spawned at the end of Azazel's shorter brimstone beam.
  • Dr. Fetus Dr. FetusCollectible Dr. Fetus icon.pngTears are replaced by bombs that benefit from bomb-enhancing effects and slide for a fixed time after being fired./Epic Fetus Epic FetusCollectible Epic Fetus icon.pngIsaac's tears are replaced with guided missiles, like those used by the Doctor's Remote./Ipecac IpecacCollectible Ipecac icon.pngReplaces tears with explosive and poisoning projectiles fired in an arc from the mouth.: Overrides Mysterious Liquid.
    • Added in Afterbirth: Explosions caused by these items will cause a large pool of creep where the explosion occurred.
  • Fire Mind Fire MindCollectible Fire Mind icon.pngGrants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion.: Mysterious Liquid removes explosion chance, but fire damage over time is preserved.
    • Added in Afterbirth Tears not only correctly retain explosion chance, but if the explosion occurs, creep generates in the entire explosion radius.
  • Added in Afterbirth †Haemolacria HaemolacriaCollectible Haemolacria icon.pngTears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay.: Only the main tear spawns creep.
  • Added in Afterbirth †Lachryphagy LachryphagyCollectible Lachryphagy icon.pngIsaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage.: Only the burst tears spawns creep.
  • Lost Contact Lost ContactCollectible Lost Contact icon.pngEvery tear has a small shield which will allow it to block one enemy projectile.: Overrides Mysterious Liquid.
    • Added in Afterbirth † The combination works as expected, with tears spawning liquid even when stopping enemy shots.
  • The Ludovico Technique The Ludovico TechniqueCollectible The Ludovico Technique icon.pngInstead of firing tears, Isaac controls one floating tear that hover over obstacles. This tear deals constant damage when held in place over an enemy.: Mysterious Liquid's graphical effect remains, but no creep is dropped because the tear never falls.
    • Added in Afterbirth Pools the size of the tear constantly form on the ground dealing large amounts of damage to any non-flying enemy inside the tear.
  • Piercing tears: Tears will not leave creep when they hit and pass through an enemy, and will only leave creep when they hit an obstacle or run out of range.
  • Spectral tears: Tears only spawn creep after they land, not while passing through obstacles.
  • Strange Attractor Strange AttractorStrange Attractor Rebirth Icon.pngPickups, trinkets, and monsters are magnetically attracted to Isaac's tears.: Overrides Mysterious Liquid.
    • Added in Afterbirth † The combination works as expected.
  • Technology TechnologyTechnology Icon.pngReplaces tears with a piercing laser with unlimited range.: Overrides Mysterious Liquid.
    • Added in Afterbirth The laser spawns pools of liquid always when it hits obstacles and occasionally on enemies.

In-game Footage[edit | edit source]

Seeds[edit | edit source]

 PC  ABP0 1DJA (Treasure room adjacent to spawn)

 PC  QXAX ZJYL (Treasure room adjacent to spawn)

 PS4  V8ZG HD31 (First floor treasure room)

 Vita  2J39 EANS (Treasure room adjacent to spawn)

 Switch  HLL1 RW2R (Treasure room adjacent to spawn)