
Upon picking up all 3 items from the following list, Isaac will heal half of a red heart each time a pile of poop is destroyed.
Name
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ID
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Icon
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Quote
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Description
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E Coli
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236
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Turdy touch
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Gives "Turdy Touch" Effect. Enemies that touch Isaac are changed into poop.
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- Despite being poop-themed,
Skatole
All types of fly except Boom Fly and Red Boom Fly become passive and slowly move towards Isaac. Does not prevent contact damage.,
Butt Bombs
Gives +5 bombs and makes all bombs Butt Bombs that fill the room with gas, damaging and confusing all enemies.,
No. 2
Continuously firing tears for several seconds causes Isaac to drop a Butt Bomb. Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time., and
Petrified Poop
Greatly increases the chances of a pickup dropping when destroying poop. do not count towards the transformation.
- Poop created with
Flush!
Changes all enemies in the room into poop. Does not work on all enemies (Knights and bosses are immune). Instantly kills Dingle, Dangle, and Brownie. and
E Coli
Gives "Turdy Touch" Effect. Enemies that touch Isaac are changed into poop. do not heal Isaac when he has this transformation.
- This transformation is easier to obtain using ???, since ??? starts with
The Poop
Spawns a pile of poop where the character is standing and knocks nearby monsters back. May yield pickups like regular poop.. However, it is useless because ??? has no red hearts.