Major changes are coming to the Wiki! To learn more and let your voice be heard, please go here.

Additionally, we are currently experiencing some bugs and glitches. We're working on fixing them, but please be aware this means certain images, such as the collection grid for items, will be replaced by errors for the time being.


From Binding of Isaac: Rebirth Wiki
Jump to: navigation, search
Font TeamMeat P.pngFont TeamMeat H.pngFont TeamMeat D.png
Item icon
Item altar
Table dividing line 1.png
Character appearance
Table dividing line 2.png
Shop Shop|- Treasure Room Treasure Room
Table dividing line 3.png
Added in Afterbirth(page 1, column 12, row 4)
Removed in Afterbirth(page 1, column 2, row 8)

PHD is a passive item.

Effects[edit | edit source]

  • Identifies all pills upon pickup.
  • Converts some "bad" pills into their "good" counterparts:
    • All "stat down" pills into "stat up" pills
    • Bad Trip into Balls of Steel
    • Amnesia into I Can See Forever
    • Added in Afterbirth † ??? into Telepills
    • Added in Afterbirth † Addicted into Percs!
    • Added in Afterbirth † I'm Excited!!! into I'm Drowsy...
    • Added in Afterbirth † Paralysis into Pheromones
    • Added in Afterbirth † Retro Vision into I can see forever!
    • Added in Afterbirth † R U A Wizard? into Power Pill!
    • Added in Afterbirth † X-Lax into Something's wrong...
  • Spawns a pill.
  • Replenishes 2 red hearts.
  • Adds 0-2 coins to the payout every time you use the Blood Donation Machine or IV Bag.

Synergies[edit | edit source]

  • Mom's Bottle of Pills Mom's Bottle of PillsMom's Bottle of Pills Icon.png6 roomsGives Isaac a random pill, and will cause him to drop any held Q-slot item (If any). The player will only receive six different pill types in one playthrough.: Generated pills are more beneficial.
  • Safety Cap Safety CapSafety Cap Icon.pngImproves the chance of Pills dropping after clearing a room, and chance of finding a Pill when opening a Chest. & Little Baggy Little BaggyLittle Baggy Icon.pngIsaac can hold 2 pills at once and all cards are replaced by pills.: Beneficial pills can be found more often.
  • IV Bag IV BagIV Bag Icon.pngUnlimitedUpon activation, Isaac loses a half-heart (one whole heart in The Womb onwards) for a random amount of coins, similar to the blood donation machine.: Better Coin payout for each time used.
  • Added in Afterbirth †Acid Baby Acid BabyAcid Baby Icon.pngSpawns a familiar that drops random pills every 2 rooms cleared. Upon using a pill, all enemies in the room are poisoned.: Drops a pill every 2 rooms.

Notes[edit | edit source]

  • The following pill types are neutral and do not have a "good" equivalent, or are otherwise left unchanged by PHD.
    • Added in Afterbirth ???
      • Added in Afterbirth † Converted to Telepills
    • Explosive Diarrhea
    • Hematemesis
    • I Found Pills
    • Added in Afterbirth Infested!
    • Added in Afterbirth Infested?
    • Added in Afterbirth One makes you small
    • Added in Afterbirth One makes you larger
    • Paralysis
      • Added in Afterbirth † Converted to Pheromones
    • Pheromones
    • Added in Afterbirth Power Pill!
    • Pretty Fly
    • Puberty
    • R U A Wizard?
      • Added in Afterbirth † Converted to Power Pill!
    • Added in Afterbirth Re-Lax
    • Telepills
  • Bad pills already obtained/dropped will be converted to their "good" counterparts.
  • If PHD is rerolled by the D4 D4D4 Icon.png6 roomsRerolls all of Isaac's items. or a Dice Room, you'll lose all pills being beneficial or neutral but they will still all be identified when you pick them up.

In-game Footage[edit | edit source]

Seeds[edit | edit source]

 PC  49BH 7C4X (Treasure Room adjacent to spawn).

 Vita  F1MK 02T4 (Treasure Room adjacent to spawn).

 Switch  1RY7 20CH (First floor shop, half off)

The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item Pools Item Pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets