Pestilence

From Binding of Isaac: Rebirth Wiki
Jump to: navigation, search
Boss Pestilence name.png
Boss versus screen image
 
 
TableDividingLine1.png
 
In-game appearance
TableDividingLine2.png
 
Boss
Stage caves.pngStage catacombs.pngStage flooded caves.png
Super Secret Room Icon.png
Mini-Boss
Stage cathedral.pngStage sheol.png
Stage chest.pngStage dark room.png
TableDividingLine3.png
 
Ball of Bandages Ball of Bandages
Ball of Bandages Icon.pngOrbiting familiar that deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Cube of Meat.

Cube of Meat Cube of Meat
Cube of Meat Icon.pngOrbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages.
 
The Harbingers Defeat Mom for the 1st time
The HarbingersThe Harbingers

Pestilence is the horseman of Chapter 2.

Behavior[edit | edit source]

Phase 1[edit | edit source]

  • Pestilence will float around the room, leaving a trail of poison.
  • In addition to the trail of poison, it will fire explosive projectiles at Isaac which too, leave poison.
  • Pestilence can also summon up to four Chargers or Spitties.

Phase 2[edit | edit source]

  • Pestilence is now headless.
  • It will keep firing the explosive projectiles at Isaac.
  • Instead of Chargers or Spitties, Pestilence will summon Attack Flies.

Champion versions[edit | edit source]

  • White: This version leaves a trail of white creep, which slows the player down and shoots 6 bullets away from itself instead of explosive shots. It spawns Spiders instead of flies in Phase 2.

Gallery[edit | edit source]

Unlockable achievements[edit | edit source]

Trivia[edit | edit source]

  • Pestilence appeared in the original Binding of Isaac.
  • Pestilence, while very often portrayed as one of the Four Horsemen of the Apocalypse in popular culture, is actually not present in the Bible at all (see Rev 6:2) and is an example of incorrect interpretation. The canonical Four Horsemen are Conquest (white), War (red), Famine (black) and Death (pale).
  • Pestilence means a virulent or fatal disease epidemic.
    • The entirety of Pestilence's offense deals with poison and bugs that are associated with rot.
  • Pestilence is the only Harbinger that does not have a charge attack.
  • Pestilence’s head resembles The Husk.
  • Pestilence makes a "Hey!" sound when launching explosive projectiles at Isaac. Famine makes the same noises when spitting shots at Isaac at its second phase.


Bosses Boss Monstro.png
Chapter 1
Stage basement.png
Stage cellar.png
Stage burning basement.png
Blighted OvumDingleThe Duke of FliesFamineFistulaGeminiGurglingsThe HauntLarry Jr.MonstroPinStevenWidow
Added in Afterbirth DangleLittle HornRag ManTurdlings
Chapter 2
Stage caves.png
Stage catacombs.png
Stage flooded caves.png
Carrion QueenC.H.A.D.ChubDark OneGurdyGurdy Jr.The HollowThe HuskMega FattyMega MawPeepPestilencePolycephalusThe Wretched
Added in Afterbirth The ForsakenThe FrailThe Stain
Added in Afterbirth † Big HornRag Mega
Chapter 3
Stage depths.png
Stage necropolis.png
Stage dank depths.png
The AdversaryThe BloatThe CageThe GateGishLokiMask Of InfamyMonstro IIWarMom
Added in Afterbirth Brownie
Added in Afterbirth † Sisters Vis
Chapter 4
Stage womb.png
Stage utero.png
Stage scarred womb.png
BlastocystThe BloatConquestDaddy Long LegsDeathLokiiMama GurdyMr. FredScolexTeratomaTriachnidMom's HeartIt Lives
Added in Afterbirth † Sisters VisThe Matriarch
Added in Afterbirth Blue Womb
???
Added in Afterbirth Hush
Chapter 5
Stage sheol.png
Stage cathedral.png
SatanIsaac
Chapter 6
Stage dark room.png
Stage chest.png
???The LambMega Satan
Added in Afterbirth Greed Mode
Ultra Greed
Added in Afterbirth Ultra Greed
Added in Afterbirth † Ultra Greedier
Added in Afterbirth † The Void
Stage the void.png
Added in Afterbirth † Delirium
Chapters 1-4 The FallenThe Headless Horseman


The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
MainPageAchievements.png Achievements MainPageAttributes.png Attributes MainPageBosses.png Bosses TarotCard.png Cards and Runes MainPageChallenges.png Challenges MainPageChapters.png Chapters
Isaac App.png Characters MainPageBabies.png Co-op MainPageItems Small.png Items Item Pools Item Pools MainPageMonsters.png Monsters MainPageObjects.png Objects
Red heart.png Pickups BlueBlue.png Pills MainPageRooms.png Rooms MainPageSeeds2.png Seeds Guppy App.png Transformations The Left Hand Icon.png Trinkets