Pestilence

Pestilence
Base HP
280
Stage HP
0
Found In
Boss Mini-Boss (Later Floors)
Dropped Items
Ball of Bandages Cube of Meat

Pestilence is a boss that can appear in The Caves, The Catacombs, and the Flooded Caves. It is one of the four Harbingers, and the horseman of Chapter 2.

Behavior

Phase 1

• Pestilence will float around the room, leaving a trail of poison.
• In addition to the trail of poison, it will fire explosive projectiles at Isaac which too, leave poison.
• Pestilence can also summon up to four Chargers or Spitties.

Phase 2

• Pestilence is now headless.
• It will keep firing the explosive projectiles at Isaac.
  
• Instead of Chargers or Spitties, Pestilence will summon Attack Flies.

Champion versions

• White: This version leaves a trail of white creep, which slows the player down and shoots 6 bullets away from itself instead of explosive shots. It spawns Spiders instead of flies in Phase 2.

Unlockable achievements

• Book of Revelations - Defeat a Harbinger for the 1st time.

Gallery

• 

  Pestilence ingame.

• 

  Pestilence in his second phase.

• 

  Pestilence as seen in Isaac's last will.

Trivia

• Pestilence appeared in the original Binding of Isaac.
• Pestilence, while very often portrayed as one of the Four Horsemen of the Apocalypse in popular culture, is actually not present in the Bible at all (see Rev 6:2) and is an example of incorrect interpretation. The canonical Four Horsemen are Conquest (white), War (red), Famine (black) and Death (pale).
• Pestilence means a virulent or fatal disease epidemic.
  • The entirety of Pestilence's offense deals with poison and bugs that are associated with rot.
• Pestilence is the only Harbinger that does not have a charge attack.