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Font TeamMeat P.pngFont TeamMeat l.pngFont TeamMeat a.pngFont TeamMeat c.pngFont TeamMeat e.pngFont TeamMeat b.pngFont TeamMeat o.png
Item icon
Item altar
Table dividing line 1.png


Table dividing line 2.png

4 rooms 4 rooms

Shop Shop
Greed mode only Shop Shop
Table dividing line 3.png

(page 3, column 3, row 6)
Added in Afterbirth

Placebo is an activated item added in Afterbirth.

Effect[edit | edit source]

  • Mimics the effect of Isaac's held pill, like Blank Card Blank Card does with cards or runes.
    • Does not consume Isaac's held pill.
    • Does not mimic cards or runes.

Synergies[edit | edit source]

Interactions[edit | edit source]

  • Starter Deck Starter Deck: All pills are replaced by cards, rendering Placebo useless.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Placebo is a medicine or procedure prescribed for the psychological benefit to the patient rather than for any physiological effect.

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