Hello there! We are conducting a survey to better understand the user experience in making a first edit. If you have ever made an edit on Gamepedia, please fill out the survey. Thank you!


From Binding of Isaac: Rebirth Wiki
Jump to: navigation, search
Font TeamMeat P.pngFont TeamMeat l.pngFont TeamMeat a.pngFont TeamMeat c.pngFont TeamMeat e.pngFont TeamMeat n.pngFont TeamMeat t.pngFont TeamMeat a.png
Item icon
Item altar
Table dividing line 1.png
Character appearance
Table dividing line 2.png
Boss Boss
Table dividing line 3.png
Added in  Afterbirth(page 2, column 15, row 5)
Removed in Afterbirth(page 3, column 5, row 2)

Placenta is a passive item.

Effects[edit | edit source]

  • Grants one full Heart Container when picked up.
  • Isaac has a chance to regenerate half of a red heart every one minute of gameplay.

Notes[edit | edit source]

  • The regeneration can happen multiple times in the same room, so there is no need to move between rooms to continue regeneration.
  • It is possible to regenerate all missing hearts by simply standing in the same room for a while. Players may want to take a short break with the game not paused in order to regenerate all of their health.
  • Regeneration does not occur when standing in a Crawl Space.
  • Added in  Afterbirth Regeneration occurs with Keeper; it will restore a full health coin for him.
  • Added in Afterbirth † Regeneration occurs with The Forgotten, restoring a third of a bone heart.
  • Regeneration will not occur for ???, as he only has soul hearts.

Synergies[edit | edit source]

  • Gnawed Leaf Gnawed LeafGnawed Leaf Icon.pngAfter standing still and not shooting for a short time, Isaac turns invincible until he moves or shoots.: Allows Isaac to safely regenerate in any room.

Interactions[edit | edit source]

  • Maggy's Bow Maggy's BowMaggy's Bow Icon.pngGives one heart container and doubles the healing provided by red hearts.: No effect on regen.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • A Placenta is an organ that forms from the mother's uterus during pregnancy that supports the unborn child during development until it is expelled during childbirth. In some cultures, it is a common practice for the mother and/or child to eat the expelled placenta.
    • This, like many other things Isaac does, is medically inadvisable.

Seeds[edit | edit source]

 PC  EPBF FS6M (Basement I boss)

 PC  419H 1DQM (Basement I boss, Gnawed Leaf in first floor item room)

Bugs[edit | edit source]

Bug Bug! Going into a Ventricle Razor portal at the same time the effect of Placenta is triggered will cause the effect to trigger in rapid succesion, effectively healing Isaac to full health.

The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item Pools Item Pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets