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Status Effects

From Binding of Isaac: Rebirth Wiki
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Disambig.png This article is about effects which can be inflicted on Monsters. For the different kinds of effects which Isaac's primary weapon can have, see Tear Effects.

Status Effects are special effects that can be inflicted on an enemy from a variety of sources, such as tears, bombs, and items. Each status effect has a colour and symbol/effect associated with them for easy identification. These colourations are not to be confused with champions.

Effects[edit | edit source]

Effect Appearance Description
Burn Burn Effect.png Afflicted enemies take 4 to 6 fire damage over time, like poison. Afflicted enemies will be tinted orange for the duration and have a fire symbol above them.

Added in  Afterbirth Afflicted enemies will sustain double Isaac's tear damage over time.

Charm Charm Effect.png Afflicted enemies will temporarily fight on Isaac's side, running toward other enemies and damaging them for 25% of their maximum HP per touch, 5 damage with half heart projectiles and 10 with full heart ones. If no other enemies are in the room, a charmed enemy will instead run towards Isaac. (Charmed enemies can still hurt Isaac.) Afflicted enemies will be tinted pink for the duration and have a heart symbol above them. Most enemies with ranged attacks will not fire them.

Added in Afterbirth † Charmed enemies will prioritize non-charmed enemies and won't target invincible enemies. Charmed Portals will also spawn friendly enemies.

Confusion Confusion Effect.png Afflicted enemies are slowed and walk around randomly. While confused, most non-boss enemies will be unable to attack. Afflicted enemies will be tinted pale gray and have stars above them.
Fear Fear Effect.png Afflicted enemies are scared of Isaac and will run away from him. While scared, most non-boss enemies will be unable to attack or charge towards Isaac. Afflicted enemies will be tinted purple and have a skull symbol above them.
Petrified Petrified Effect.png Afflicted enemies are stopped in place. They cannot move or attack. Afflicted enemies will be shaded brown-gray, as if turned to stone (unless petrified by Midas' Touch, in which case they will be shaded gold).
Poison Poison Effect.png Afflicted enemies sustain 4 to 6 damage over time. Afflicted enemies will be tinted green and have a bubbly effect surrounding them.

Added in  Afterbirth Afflicted enemies will sustain double Isaac's tear damage over time.

Slow Slow Effect.png Afflicted enemies are slowed down. Any projectiles they shoot will also be slowed down. Attacks that end when the enemy runs out of momentum, such as the charging attacks of Gurdy Jr. and Dingle, will be vastly shortened in duration. Depending on the item that triggers the slow effect, afflicted enemies will be tinted black or white with a snail icon above them.
Added in  Afterbirth
Friendly
Friendly Effect.png Afflicted enemies are permanently charmed and will fight on Isaac's side until they die. Most enemies under this effect will follow Isaac across rooms, like a familiar. Friendly enemies cannot hurt Isaac. Friendly enemies are not tinted, but still have heart effects.
Added in  Afterbirth
Shrink
Gaper.png Afflicted enemies are shrunken and will run away from Isaac. Isaac can walk over shrunken enemies to kill them.
Added in Afterbirth †
Bleed
Bleed Effect.png Afflicted enemies take damage equal to 10% of their maximum health every 5 seconds.

Notes[edit | edit source]

  • Host-type enemies will take burn and poison damage even if their skull is down, and all status effects can be applied by tears even if their skulls are down.

Burn[edit | edit source]

Passive Items that cause burning[edit | edit source]

Name ID Icon Quote Description
Fire Mind 257 Fire Mind Flaming tears Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion.

Charm[edit | edit source]

Activated Items that cause charming[edit | edit source]

Name ID Icon Quote Description
Added in  Afterbirth Kidney Bean 421
Kidney Bean
2 rooms
Love toots! Upon use, Isaac farts, charming all nearby enemies.

Passive Items that cause charming[edit | edit source]

Name ID Icon Quote Description
Ball of Bandages 207 Ball of Bandages Gotta lick 'em all! Orbiting familiar that deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Cube of Meat.
Added in  Afterbirth Betrayal 391 Betrayal Turn your enemy Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac.
Added in Afterbirth † Bozo 513 Bozo Party time! Increases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.
Added in  Afterbirth Glitter Bombs 432 Glitter Bombs Prize bombs! Gives Isaac 5 bombs, and makes Isaac's bombs have a chance to drop random pickups or charm enemies when they explode.
Mom's Eyeshadow 200 Mom's Eyeshadow Charm tears Tears have a chance to charm enemies.

Pills that cause charming[edit | edit source]

Pill Effect
Pheromones

Charms all enemies in the room for a short period of time.

Notes[edit | edit source]

  • First stage of Ball of Bandages cannot charm enemies. See Ball of Bandages for details.
  • Charmed enemies will still target Isaac if they are the only enemy in the room.

Confusion[edit | edit source]

Passive Items that cause confusion[edit | edit source]

Name ID Icon Quote Description
Butt Bombs 209 Butt Bombs Toxic blast +5 bombs Gives +5 bombs and makes all bombs Butt Bombs that fill the room with gas, damaging and confusing all enemies.
Added in Afterbirth † Glaucoma 460 Glaucoma Blind tears! Adds a chance to shoot concussive tears, causing enemies to walk around randomly.
Iron Bar 201 Iron Bar Concussive tears Increases damage by 0.3 and adds a chance to shoot concussive tears, causing enemies to walk around randomly.

Trinkets that cause confusion[edit | edit source]

Name ID Icon Quote Description
Added in  Afterbirth Faded Polaroid 69 Faded Polaroid You feel faded Occasionally causes Isaac to blend into the ground, which briefly confuses all enemies in the room.

Fear[edit | edit source]

Activated Items that cause fear[edit | edit source]

Name ID Icon Quote Description
The Gamekid 93
The Gamekid
6 rooms
Temporary Man-Pac Upon use, turns the character into a into a Pac-Man-like creature for 5 seconds, granting invulnerability, inflicting fear on all enemies, and replenishing half a red heart container for every two enemies killed.
Mom's Pad 41
Mom's Pad
3 rooms
Gross... Upon use, inflicts fear to all enemies in the room for 5 seconds.

Passive Items that cause fear[edit | edit source]

Name ID Icon Quote Description
Abaddon 230 Abaddon Evil + DMG up + fear shot Increases damage and speed, removes all red heart containers, grants six black hearts, and adds a chance to shoot fear tears.
Added in Afterbirth † Bozo 513 Bozo Party time! Increases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.
Dark Matter 259 Dark Matter Fear shot Increases Damage by 1 and adds a chance to shoot fear tears.
Mom's Perfume 228 Mom's Perfume Fear shot Adds a chance to shoot fear tears and decreases tear delay by 1.
Added in  Afterbirth My Shadow 433 My Shadow Me! And my shaaaadow! Each time Isaac takes damage, inflicts fear on all enemies in the room and spawns a black friendly Charger that will attack enemies. The Charger will be killed if it is damaged too much.
Added in  Afterbirth Spear of Destiny 400 Spear of Destiny Your destiny In addition to tears, Isaac now holds a spear in front of him which deals damage equal to 2 times his tear damage, and occasionally inflicts fear. The spear cannot be thrown, but deals damage while it is in contact with an enemy.

Petrification[edit | edit source]

Activated Items that petrify enemies[edit | edit source]

Name ID Icon Quote Description
The Boomerang 338
The Boomerang
4 seconds
It will never leave you Throws a short-range boomerang which does a bit of damage and has a high chance to stun the enemy for 2 seconds. Can also be used to grab pickups.
Added in  Afterbirth Mega Bean 351
Mega Bean
3 rooms
Giga fart! When used, the Mega Bean will freeze all enemies in the current room for a couple of seconds, deal 5 damage and poison any enemies near Isaac, and send a wave of spikes that deals 10 damage across the room in the direction Isaac is facing.
Mom's Bra 39
Mom's Bra
3 rooms
Mass Fear Upon use, petrifies all enemies in the current room for approximately 4 seconds.

Passive Items that petrify enemies[edit | edit source]

Name ID Icon Quote Description
Added in  Afterbirth Charged Baby 372 Charged Baby Bbbzzzzzt! A familiar that drops a Little Battery every 4 rooms. Has a small chance to freeze all enemies in the room when hit.
Added in Afterbirth † Dad's Ring 546 Dad's Ring Father's blessing Creates a ring of light around Isaac that petrifies enemies in contact.
Added in Afterbirth † Eye of Greed 450 Eye of Greed Gold tears! Adds a chance to fire tears that temporarily stun enemies and turn them into gold. Any enemy killed while in this state will drop coins.
Midas' Touch 202 Midas' Touch Golden touch Enemies that touch you are stunned and turn gold. Any enemy killed while in this state will drop a coin.
Mom's Contacts 110 Mom's Contacts Freeze effect Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. Range up.

Poison[edit | edit source]

Activated Items that poison enemies[edit | edit source]

Name ID Icon Quote Description
The Bean 111
The Bean
1 rooms
Toot on command Isaac releases bad gas, poisoning any enemy in close vicinity.
Bob's Rotten Head 42
Bob's Rotten Head
3 rooms
Reusable ranged bomb Upon use, Isaac holds a poison bomb which can be thrown towards any of the four cardinal points and explodes on impact.
Added in  Afterbirth Mega Bean 351
Mega Bean
3 rooms
Giga fart! When used, the Mega Bean will freeze all enemies in the current room for a couple of seconds, deal 5 damage and poison any enemies near Isaac, and send a wave of spikes that deals 10 damage across the room in the direction Isaac is facing.

Passive Items that poison enemies[edit | edit source]

Name ID Icon Quote Description
Added in Afterbirth † Acid Baby 491 Acid Baby Pills pills pills! Spawns a familiar that drops random pills every 2 rooms cleared. Upon using a pill, all enemies in the room are poisoned.
The Black Bean 180 The Black Bean Toot on touch When taking damage, Isaac farts, causing poison damage to all enemies in range.
Bob's Brain 273 Bob's Brain Explosive thoughts Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds.
Bob's Curse 140 Bob's Curse +5 poison bombs Gives 5 bombs and grants all bombs poison effect.
The Common Cold 103 The Common Cold Poison Damage Adds a chance to shoot poison tears, dealing damage over time when inflicted.
Ipecac 149 Ipecac Explosive shots Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth.
Scorpio 305 Scorpio Poison tears Grants poison tears, which deal damage over time when inflicted.
Added in  Afterbirth Serpent's Kiss 393 Serpent's Kiss The kiss of death Tears now have a random chance to apply a poison effect, causing 4 or 6 damage per tick to enemies (Similar to The Common Cold item). Isaac now deals poison damage on contact with enemies similar to The Virus item (Damage over time 4 or 6 per tick). Enemies that were poisoned have a chance to drop a black heart when killed.
Added in  Afterbirth Toxic Shock 350 Toxic Shock Mass poison Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short lasting pool of green creep on the ground.
The Virus 13 The Virus Poison touch Inflicts poison to enemies who make contact with Isaac. Speed down.

Trinkets that grant poison tears[edit | edit source]

Name ID Icon Quote Description
Pinky Eye 30 Pinky Eye Poison shots Adds a 10% chance to shoot a poison tear, dealing damage over time when inflicted.

Pills that poison enemies[edit | edit source]

Pill Effect
Bad Gas

Isaac farts, poisoning enemies around him.

Slow[edit | edit source]

Activated Items that slow enemies[edit | edit source]

Name ID Icon Quote Description
The Hourglass 66
The Hourglass
2 rooms
Temporary enemy slowdown Upon activation, enemies and their projectiles are slowed down for a short duration.
Spider Butt 171
Spider Butt
2 rooms
Mass enemy slowdown + damage Damages all enemies in the room and slows them and their projectiles down.

Passive Items that slow enemies[edit | edit source]

Name ID Icon Quote Description
Ball of Tar 231 Ball of Tar Sticky feet... Adds a chance to shoot slowing tears and the character leaves a trail of slowing creep behind as he moves, impeding enemies' speed.
Broken Watch 337 Broken Watch I think it's broken Chance upon entering a room to slow down or speed up every enemy and their attacks. The chance to slow enemies is quite higher than the chance to speed them up.
Added in  Afterbirth Censer 387 Censer Peace be with you Gives Isaac a golden censer familiar which creates a huge aura of light that slows down any enemies and enemy shots inside it.
Juicy Sack 266 Juicy Sack Sticky babies A familiar that follows behind Isaac. It drips a trail of creep, which slows enemies, and spawns 1-2 blue spiders after each room.
Little Gish 99 Little Gish Sticky friend Spawns a familiar that follows Isaac around and fires slowing tears, impeding enemies' speed.
Added in  Afterbirth Night Light 425 Night Light Scared of the dark? A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots.
Spider Bite 89 Spider Bite Slow effect Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them.
Stop Watch 232 Stop Watch Let's slow this down a bit Removed in Afterbirth Automatically inflicts slow to all enemies in every room.
Added in  Afterbirth Upon taking damage, inflicts slow to all enemies for the current room.

Notes[edit | edit source]

Friendly Added in  Afterbirth[edit | edit source]

Activated Items that make enemies friendly[edit | edit source]

Name ID Icon Quote Description
Added in  Afterbirth Friendly Ball 382
Friendly Ball
3 rooms
Gotta fetch 'em all! Throwing the ball at an enemy instantly kills it and captures it. The captured enemy can later be released and will be friendly, fighting for Isaac and persisting between rooms.

Active Items that create friendly enemies[edit | edit source]

Name ID Icon Quote Description
Added in Afterbirth † Book of the Dead 545
Book of the Dead
4 rooms
Rise from the grave Upon use, spawns a friendly Bony or an orbital bone for each enemy killed in the current room.

Passive Items that create friendly enemies[edit | edit source]

Name ID Icon Quote Description
Added in  Afterbirth My Shadow 433 My Shadow Me! And my shaaaadow! Each time Isaac takes damage, inflicts fear on all enemies in the room and spawns a black friendly Charger that will attack enemies. The Charger will be killed if it is damaged too much.
Added in Afterbirth † Shade 468 Shade It follows Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies.
Added in Afterbirth † Poke Go 505 Poke Go Gotta catch em... Upon entering a room with enemies in it, has a chance to spawn a random friendly enemy that persists across rooms.
Added in Afterbirth † Mystery Egg 539 Mystery Egg Sacrificial insemination Spawns an egg familiar, which cracks and turns into a random friendly enemy when Isaac is hurt. The egg regenerates upon entering a different room.

Shrink Added in  Afterbirth[edit | edit source]

Passive Items that grant shrinking tears[edit | edit source]

Name ID Icon Quote Description
Added in  Afterbirth God's Flesh 398 God's Flesh Shrink shot Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size and also run away from Isaac. Shrunk enemies can be crushed and killed by walking over them.

Bleed Added in Afterbirth †[edit | edit source]

Passive Items that inflict bleed[edit | edit source]

Name ID Icon Quote Description
Added in Afterbirth † Backstabber 506 Backstabber Watch your back! Has a chance to fire tears that inflict bleeding on enemies, causing them to slowly take damage over time.
Added in Afterbirth † Mom's Razor 508 Mom's Razor It's sharp! Spawns an orbiting razor that damages enemies it touches and inflicts bleeding on enemies, causing them to slowly take damage over time.

Random[edit | edit source]

These items inflict random status effects on enemies.

Passive Items that inflict random effects[edit | edit source]

Name ID Icon Quote Description
Added in  Afterbirth GB Bug 405 GB Bug Game breaking bug, right away! A glitch familiar that bounces around the room and applies a random status effect to any enemies it comes into contact with and has a chance to re-roll pickups that it passes over.
Added in  Afterbirth Spider Mod 403 Spider Mod Mod buddy! Displays Isaac's tear damage and enemy health bars. Spawns a gray spider familiar that wanders around and inflicts a random status effect on any enemies it comes into contact with. Occasionally spawns a blue spider upon clearing a room.


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