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Boss Polycephalus name.png
Boss versus screen image
Table dividing line 1.png
In-game appearance
Table dividing line 2.png
Stage catacombs.pngStage flooded caves.png
Super Secret Room Icon.png
Double Trouble
Stage caves.png
Stage depths.pngStage necropolis.pngStage dank depths.png
Stage womb.pngStage utero.pngStage scarred womb.png
Stage sheol.png
Stage chest.pngStage dark room.png
Table dividing line 3.png
Boss Boss

Polycephalus is a boss that can appear in The Catacombs and the Flooded Caves. It is a mass of underdeveloped heads sprouting from a giant half buried one.

Behavior[edit | edit source]

Polycephalus's attacks consist of burrowing underground and then attacking Isaac in a variety of ways.

  • He may spray out a barrage of shots towards the player.
  • He may fire a spread-shot of three shots at the player.
  • He may summon a Round Worm.
  • He may shoot out eight tears around him.

When Polycephalus bursts upwards is random, however the player can delay him appearing by continuing to move, and can force him to appear by standing still. In the latter case Polycephalus will appear directly beside the player.

Champion Versions[edit | edit source]

  • Added in Afterbirth Red: Summons Para-Bites instead of Round Worms. All blood shot attacks are replaced with a ring of six blood shots.
  • Added in Afterbirth Pink: Two Polycephaluses, each with half health, replace the normal Polycephalus. They do not spawn Round Worms.

Gallery[edit | edit source]

Notes[edit | edit source]

Trivia[edit | edit source]

  • Added in Afterbirth The Stain is the posthumous version of it.
  • Polycephaly is the condition of having more than one head.
  • Polycephalus shares its name with a cactus.
  • Polycephalus is one of three bosses to have its posthumous version in the same chapter, the others being Gemini having Blighted Ovum in Chapter 1, and Chub having Carrion Queen in Chapter 2.
    • However, Polycephalus is the only one of them to have its posthumous version in the same environments as well, sharing both The Catacombs and the Flooded Caves with The Stain. The only difference is that The Stain can appear in The Caves as well, where Polycephalus cannot.
  • Polycephalus is one of the three bosses that can be spawned by It Lives, the other two being Chub and Teratoma.

Bosses Boss Monstro.png
Chapter 1
Stage basement.png
Stage cellar.png
Stage burning basement.png
Blighted OvumDingleThe Duke of FliesFamineFistulaGeminiGurglingsThe HauntLarry Jr.MonstroPinStevenWidow
Added in Afterbirth DangleLittle HornRag ManTurdlings
Chapter 2
Stage caves.png
Stage catacombs.png
Stage flooded caves.png
Carrion QueenC.H.A.D.ChubDark OneGurdyGurdy Jr.The HollowThe HuskMega FattyMega MawPeepPestilencePolycephalusThe Wretched
Added in Afterbirth The ForsakenThe FrailThe Stain
Added in Afterbirth † Big HornRag Mega
Chapter 3
Stage depths.png
Stage necropolis.png
Stage dank depths.png
The AdversaryThe BloatThe CageThe GateGishLokiMask Of InfamyMonstro IIWarMom
Added in Afterbirth Brownie
Added in Afterbirth † Sisters Vis
Chapter 4
Stage womb.png
Stage utero.png
Stage scarred womb.png
BlastocystThe BloatConquestDaddy Long LegsDeathLokiiMama GurdyMr. FredScolexTeratomaTriachnidMom's HeartIt Lives
Added in Afterbirth † Sisters VisThe Matriarch
Added in Afterbirth Blue Womb
Added in Afterbirth Hush
Chapter 5
Stage sheol.png
Stage cathedral.png
Chapter 6
Stage dark room.png
Stage chest.png
???The LambMega Satan
Added in Afterbirth Greed Mode
Ultra Greed
Added in Afterbirth Ultra Greed
Added in Afterbirth † Ultra Greedier
Added in Afterbirth † The Void
Stage the void.png
Added in Afterbirth † Delirium
Chapters 1-4 The FallenThe Headless Horseman
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
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