Both conditions must be met for Eve to hold it; donating 439 coins before defeating Satan with Eve will wrongly state on Eve's profile on the Character Selection Screen that she has it equipped.
Eve starts with the Razor Blade if unlocked from the Greed Machine, even if Satan has not been defeated with Eve.
It is possible to die using Razor Blade if Isaac does not have enough hearts.
The effect stacks with itself and Red Patch, which provides a similar benefit.
The item itself is a reference to the act of cutting one's self, usually at the wrists, to inflict self-harm or to commit suicide by loss of blood.
Isaac's appearance after using the item is just like the Dople.
In the original The Binding of Isaac, Razor Blade was unlocked by defeating Mom's Heart/ It Lives as Eve.
Bugs[ | ]
Bug!
As Eve, there is a very unlikely chance that using this to activate Whore of Babylon will not activate it, despite being at the correct health to do so.
Gallery[ | ]
The icon of Razor Blade as seen on the lower 3DS screen.