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|Defeat Isaac as LilithRune Bag|
Rune Bag is a passive item added in the Binding of Isaac: Afterbirth expansion.
Effects[edit | edit source]
Synergies[edit | edit source]
- BFFS!Increases the size and damage of familiars.: Increases Rune Bag's size and increases the frequency of runes dropping.
In-game Footage[edit | edit source]
Seeds[edit | edit source]
|IncubusDefeat Hush as LilithBox of FriendsDefeat Ultra Greed as LilithBig BabyDefeat Mega Satan as LilithRune BagDefeat Isaac as LilithCambion ConceptionDefeat ??? as LilithSerpent's KissDefeat Satan as LilithSuccubusDefeat The Lamb as LilithImmaculate ConceptionComplete the Boss Rush as LilithGoat Head BabyDefeat Mom's Heart on hard mode as LilithDark BabyEarn all hard mode completion marks as Lilith||EuthanasiaDefeat Delirium as LilithDualityDefeat Ultra Greedier as Lilith|
|The Binding of Isaac: Rebirth|
|Achievements||Attributes||Bosses||Cards and Runes||Challenges||Chapters|