Rune Bag

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Secret Room Treasure Room Golden Chest Treasure Room

(page 4, column 4, row 2)(page 4, column 4, row 2)

Defeat Isaac as LilithRune Bag

Rune Bag is an unlockable passive item added in the Binding of Isaac: Afterbirth expansion.

Effects

• Drops a random rune every few rooms.
  • If there are no runes unlocked, it will drop cards instead.

Synergies

• BFFS!Increases the size and damage of familiars.: Increases Rune Bag's size and increases the frequency of runes dropping.

Seeds

 Switch  9XX3 HWL2 (First Golden Treasure Room)

Lilith Unlocks
IncubusDefeat Hush as LilithBox of FriendsDefeat Ultra Greed as LilithBig BabyDefeat Mega Satan as LilithRune BagDefeat Isaac as LilithCambion ConceptionDefeat ??? as LilithSerpent's KissDefeat Satan as LilithSuccubusDefeat The Lamb as LilithImmaculate ConceptionComplete the Boss Rush as LilithGoat Head BabyDefeat Mom's Heart on hard mode as LilithDark BabyEarn all hard mode completion marks as Lilith	EuthanasiaDefeat Delirium as LilithDualityDefeat Ultra Greedier as Lilith