Secret Room (Item Pool)

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Item Pool
Normal and hard modes only Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest Red Chest Beggar Devil Beggar Key Master Added in  Afterbirth Bomb Bum
Added in  Afterbirth Greed mode only
Added in Afterbirth † Greedier mode only
Treasure Room Shop Library Curse Room Boss Secret Room Devil Room Angel Room Golden Chest

Items in this pool can be found in the Secret Room.

Activated Collectibles[edit | edit source]

Name ID Icon Quote Description
Blank Card 286
Blank Card
4 rooms
Card Mimic Has the same effect as the card or rune currently held by Isaac.
Book of Secrets 287
Book of Secrets
6 rooms
?????? Upon use, gives the effect of Treasure Map, The Compass, or Blue Map for the duration of the current floor.
Forget Me Now 127
Forget Me Now
One time use
I don't remember When activated, the level ends and is freshly regenerated with new rooms, monsters, and items. Disappears after use.
The Necronomicon 35
The Necronomicon
6 rooms
Mass room damage Damages all enemies in the room significantly.
We Need to Go Deeper! 84
We Need to Go Deeper!
6 rooms
Reusable level skip Creates a trapdoor to go to the next floor. If used in The Womb, it will create a trapdoor to Sheol, even if the player hasn't unlocked it.
Added in Afterbirth † Compost 480
2 rooms
Gain more friends! Spawns a blue spider or fly. Turns pickups in the room into blue spiders or flies.

Passive Collectibles[edit | edit source]

Name ID Icon Quote Description
1up! 11 1up! Extra life Gives an extra life. Upon death, you will respawn in the previous room with full health and lose the 1up!.
A Quarter 74 A Quarter +25 coins Adds 25 to Isaac's coin count, capping at 99.
Black Lotus 226 Black Lotus HP up x3! Grants the player one red heart container, one soul heart, and one black heart.
Bomb Bag 131 Bomb Bag Gives bombs Isaac is followed by a small bag that drops a Bomb, 1+1 Free, or a Troll Bomb every 3 rooms.
Cursed Eye 316 Cursed Eye Cursed charge shot Grants charged tears that can be fired in a tight burst of four. Getting hit while charging will teleport Isaac into another room.
Infamy 242 Infamy Damage Reduction Chance to block projectiles coming from any direction.
Lost Contact 213 Lost Contact Shielded tears Every tear has a small shield which will allow it to block one enemy projectile.
Missing No. 258 Missing No. Syntax error Randomizes all passive items upon pickup and at the start of each succeeding floor.
Missing Page 2 262 Missing Page 2 Evil up. Your enemies will pay! Gives 1 black heart. Upon taking damage that reduces Isaac's health to one heart or less, activates The Necronomicon effect, dealing 40 damage to all enemies in the room.
Mr. Mega 106 Mr. Mega Blast damage Gives Isaac 5 bombs, and makes all dropped bombs larger, which have an increased blast radius and increased damage.
Mystery Sack 271 Mystery Sack ? Spawns a familiar that follows Isaac around and has a chance to drop a heart, coin, bomb, or key after clearing a room.
Odd Mushroom 121 Odd Mushroom DMG up Grants an empty heart container. Increases damage, range and shot height while reducing speed.
Odd Mushroom 120 Odd Mushroom Fire rate up +1.7 tears, +0.3 speed, reduces damage.
Pyro 190 Pyro 99 bombs Adds 99 bombs.
Raw Liver 16 Raw Liver HP up Grants 2 Heart Containers and completely restores health.
Sack of Pennies 94 Sack of Pennies Gives money Isaac is followed by a small bag that drops a coin every 2 rooms.
Samson's Chains 321 Samson's Chains The ol' ball and chain Pull a chain and ball behind you that will damage enemies on contact and is able to break stones.
Skeleton Key 17 Skeleton Key 99 keys Sets your key count to the maximum of 99.
Transcendence 20 Transcendence We all float down here... Grants flight.
Added in  Afterbirth GB Bug 405 GB Bug Game breaking bug, right away! A glitch familiar that bounces around the room and applies a random status effect to any enemies it comes into contact with and has a chance to re-roll pickups that it passes over.
Added in  Afterbirth Key Bum 388 Key Bum He wants your keys! Spawns a portable key master that follows Isaac and collects keys, giving random chests in return.
Added in  Afterbirth Rune Bag 389 Rune Bag Rune generator A bag that follows Isaac and drops a random rune every 3 rooms.
Added in Afterbirth † Dad's Ring 546 Dad's Ring Father's blessing Creates a ring of light around Isaac that petrifies enemies in contact.
Added in Afterbirth † Eye of Greed 450 Eye of Greed Gold tears! Adds a chance to fire tears that temporarily stun enemies and turn them into gold. Any enemy killed while in this state will drop coins.
Added in Afterbirth † Greed's Gullet 501 Greed's Gullet Money = health! Grants a heart container for every 25 coins Isaac has.

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