Shopkeeper

Dead shopkeepers are present in every Shop and Secret Room, and can also be found in Vaults, Arcades, Bedrooms, and I AM ERROR rooms. Occasionally, destroying them will yield rewards.

Destroying a shopkeeper increases the chance for a Devil or Angel Room to appear by 10% for the current floor.

Normal Shopkeepers

Possible Rewards

• Nothing
• 2 random coins
• 2 spiders
• Steam SaleReduces all Shop prices by 50%, rounded down to 7 coins for an item, rounded up to 2-3 coins for a pickup. (1% chance)
• Head of the KeeperIsaac's tears become coins and now have a chance to drop pennies on the floor upon successfully hitting an enemy. (1% chance)
• CouponUpon use, makes a random item from a shop, devil deal, or black market free. (1% chance)

Special Shopkeeper

Special shopkeepers have a chance to replace regular shopkeepers. Special shopkeepers are unlocked by donating 234 coins to the Greed Machine and special hanging shopkeepers are unlocked by donating 10 coins to the Greed Machine.

Possible Rewards

• Nothing
• A nickel
• Greed
• Bloody PennyGives a 50% chance to drop a half heart when money is collected., Butt PennyIsaac will fart when he picks up a coin., Counterfeit PennyGives a 50% chance of increasing the value of every coin pickup by one., Flat PennyGives a 50% chance of spawning a key upon collecting a penny., Swallowed PennyUpon taking damage, Isaac drops a penny., or Burnt PennyGives a 50% chance to drop a bomb when money is collected..

Notes

• If the player already has Steam SaleReduces all Shop prices by 50%, rounded down to 7 coins for an item, rounded up to 2-3 coins for a pickup. and Head of the KeeperIsaac's tears become coins and now have a chance to drop pennies on the floor upon successfully hitting an enemy., shopkeepers will not drop any further pedestal items.
• Shopkeepers can be destroyed with The BoomerangThrows a short-range boomerang which does a bit of damage and has a high chance to stun the enemy for 2 seconds. Can also be used to grab pickups., Red CandleThrows a persistent flame that deals high damage and diminishes as it damages enemies or blocks shots. and The CandleThrows out a blue flame that can pass over gaps (but not through rocks). The flame damages anything in its path..
• If Isaac has Holy LightIsaac has a random chance to fire a Holy tear, which, when it hits an enemy, will spawn a Crack the Sky-style light beam on the same enemy, dealing damage. and hits an enemy near a shopkeeper with a Holy Light tear, the shopkeeper will be destroyed by the beam of light.
• With Infestation 2Spawns allied blue spiders from killed enemies., destroying shopkeepers will spawn blue spiders.
• Using the "PAC1 F1SM" special seed makes Shopkeepers invincible too.
• If Greed is spawned from the Special Shopkeeper being bombed, the doors will be locked.

Unlockable Achievements

• 

  Lucky Toe - Blow up 20 shopkeepers.

Trivia

• The shopkeeper's faces occasionally take on the appearance of certain popular Internet memes, such as "Forever Alone".