Shopkeeper

Dead shopkeepers are present in every Shop and Secret Room, and can also be found in Vaults, Arcades, Bedrooms, and I AM ERROR rooms. Occasionally, destroying them will yield rewards.

Destroying a shopkeeper increases the chance for a Devil or Angel Room to appear by 10% for the current floor.

Normal Shopkeepers

Possible Rewards

• Nothing
• 2 random coins
• 2 spiders
• Steam Sale (1% chance)
• Head of the Keeper (1% chance)
• Coupon (1% chance)

Special Shopkeeper

Special shopkeepers have a chance to replace regular shopkeepers. Special shopkeepers are unlocked by donating 234 coins to the Greed Machine and special hanging shopkeepers are unlocked by donating 10 coins to the Greed Machine.

Possible Rewards

• Nothing
• A nickel
• Greed
• Bloody Penny, Butt Penny, Counterfeit Penny, Flat Penny, Swallowed Penny, or Burnt Penny.

Notes

• If the player already has Steam Sale and Head of the Keeper, shopkeepers will not drop any further pedestal items.
• Shopkeepers can be destroyed with The Boomerang, Red Candle and The Candle.
• If Isaac has Holy Light and hits an enemy near a shopkeeper with a Holy Light tear, the shopkeeper will be destroyed by the beam of light.
• With Infestation 2, destroying shopkeepers will spawn blue spiders.
• Using the "PAC1 F1SM" special seed makes Shopkeepers invincible too.
• If Greed is spawned from the Special Shopkeeper being bombed, the doors will be locked.

Unlockable Achievements

• 

  Lucky Toe - Blow up 20 Shopkeepers.

Trivia

• The shopkeeper's faces occasionally take on the appearance of certain popular Internet memes, such as "Forever Alone".