Signs of the Zodiac

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The 12 Signs of the Zodiac are featured as passive collectible items based on the 12 astrological signs.

Items[edit | edit source]

Name ID Icon Quote Description
Aries 300 Aries Ramming speed +0.25 Speed. Running into enemies while at a high speed will deal 18 points of damage. Does not prevent contact damage.
Taurus 299 Taurus Speed down + rage is building Speed down; gains speed while in a room with enemies until gaining My Little Unicorn effect for a few seconds.
Gemini 318 Gemini Conjoined friend Suture becomes attached to Isaac, and does touch damage to enemies within its attacking range.
Cancer 301 Cancer HP up + you feel protected Adds 3 soul hearts. Grants The Wafer effect for the current room upon taking damage.
Leo 302 Leo Stompy Allows you to crush rocks when you walk over them.
Virgo 303 Virgo You feel refreshed and protected Grants a chance to trigger the Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 10 seconds. Also converts "bad pills" into "good pills".
Libra 304 Libra You Feel Balanced Gives 6 coins, 6 bombs, and 6 keys and balances out all attributes.
Scorpio 305 Scorpio Poison tears Grants poison tears, which deal damage over time when inflicted.
Sagittarius 306 Sagittarius Penetrative shot + speed up Increases speed by +0.2 and grants piercing tears.
Capricorn 307 Capricorn All stats up All stats up.
Aquarius 308 Aquarius Trail of tears A trail of blue creep is left behind Isaac, which damages enemies.
Pisces 309 Pisces Tears up + knock-back shots -1 Tear Delay, adds knock-back shots and increases tear size.

Astrological Significance[edit | edit source]

Some of the effects caused by the items in-game are directly related to their astrological significance or symbol. For example, Aquarius is portrayed as a man (Ganymede) bearing water, and in game the item causes Isaac to leave a trail of tears behind him while walking; Libra, which represents weighing scales, balances Isaac's stats.


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