Binding of Isaac: Rebirth Wiki
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Giant Cell[]

Tried using this with Repentance's Giant Cell, but the two little familiars just turned into coins when I used Sacrificial Altar. Don't know if this is an intended interaction. --Juniperbelmont (talk) 22:01, 2 April 2021 (UTC)

Untitled[]

Unlock condition (I think): Pick up goat head 5 (?) times

This unlocked immediately upon adding BP5 for me, but none of the known item based unlocks did. It seems unlikely that I've gotten Goat Head ≥5 times and Blood Clot <10 times since a counter was added. --QGrav42


Isaac's Head interaction[]

Anybody know about Isaac's Head interaction?

It interacts normally. --Sirtimmothybrentwood 20:25, 4 February 2020.

Unlock method[]

I recently started a new save file and this item unlocked after picking up Lord of the Pit. Not sure how mant times I picked it up though. It might also be connected to the total number of devil deals taken. (Comment by User:OciXCrom)

Maybe it's not linked to devil deal taking but collecting devil pool items whether from a deal or not? That would need some investigating to be certain. Frionil (talk) 13:25, 19 April 2020 (UTC)

Loss of Transformation from consuming familiars[]

Note:

If the familiars you sacrifice are attributing to a transformation then you will lose the transformation upon consuming said familiars. Feels like an important point however unclear if it should be on this page or the transformation page.

Context: Had Beezlebub from exactly 3 items ( Best Bud, Blue turret fly and psy fly) activating altar made me lose beezlebub. I just realized i consumed my psy fly RIP

The Devil? card interaction[]

If used while the player temporarily has Seraphim spawned by the "The Devil?" card, you get an item for Seraphim, but Seraphim doesn't disappear until the usual timer runs out.

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