Binding of Isaac: Rebirth Wiki
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Items

Activated Collectibles

Collectible Bob's Rotten Head iconBob's Rotten Head
  • The head deals 3 times Isaac's tear damage as poison over time instead of either 6 or 8 points.
Collectible The Book of Belial iconThe Book of Belial
  • Increases the chance to open the Devil Room or Angel Room by 12.5% after killing a boss while holding it instead of guaranting it.
Collectible Book of Revelations iconBook of Revelations
  • Increases chance for a Devil/Angel Room Door to open by 17.5% instead of 35%.
Collectible Butter Bean iconButter Bean
  • Knocks back enemy shots.
Collectible Crack the Sky iconCrack the Sky
  • The beams have a high chance to directly target enemies.
Collectible D4 iconD4
  • Previously held items are removed from the pause menu.
Collectible The D6 iconThe D6
  • Reroll an item after defeating The Fallen no longer replace the Devil Room item he drops to a random item from the normal boss item pool.
Collectible D10 iconD10
  • Fly enemies are only rerolled into other fly enemies.
  • Red flies can't be rerolled anymore (even though enemies can be rerolled into them).
Collectible Flush! iconFlush!
  • Floods the whole room with water.
  • Flushes all poop-related enemies and bosses away.
  • The ladders are covered in water but the walls are not when used inside a crawl space.
Collectible Guppy's Paw iconGuppy's Paw
  • Can no longer be used without red heart containers.
Collectible Head of Krampus iconHead of Krampus
  • Has a 50% chance to rotate all beams around the player 90 degrees, similar to Krampus' second Brimstone attack.
Collectible The Jar iconThe Jar
  • Sprite changed.
Collectible Monstro's Tooth iconMonstro's Tooth
  • Has no effect if Monstro is in the room the item is used in.
Collectible The Poop iconThe Poop
  • Knocks back enemy shots.
Collectible Scissors iconScissors
  • Its recharge time is 2 rooms instead of 6 rooms.
Collectible Undefined iconUndefined
  • Dark Room can no longer be cleared repeatedly.

Passive Collectibles

Collectible 20 20 icon20/20
  • Sprite changed.
Collectible 3 Dollar Bill icon3 Dollar Bill
  • The type of randomized tear changes every 2-3 seconds. The item appears to select two tear effects at once, perhaps staggering the times at which each of those effects change.
  • If a run is quit, and then continued, 3 Dollar Bill will keep tear effects for the current room.
Collectible Abel iconAbel
  • Abel shoots tears towards Isaac regardless of which direction Isaac is shooting.
Collectible Ball of Bandages iconBall of Bandages
  • Ball of Bandages blocks enemy shots.
Collectible Bob's Brain iconBob's Brain
  • Bob's Brain is fired directly from where it is located in the chain of familiars behind Isaac, making aiming it slightly more difficult.
Collectible Bomb Bag iconBomb Bag
Collectible Box iconBox
  • Can drop a Gold Bomb.
Collectible The Common Cold iconThe Common Cold
  • The poison hits twice, dealing a total of double Isaac's damage.
Collectible Dr. Fetus iconDr. Fetus
  • Each bomb deals 5 times the character's normal tear damage instead of 3, plus a flat 30 damage. The flat 30 is not affected by damage multipliers.
Collectible Lord of the Pit iconLord of the Pit
  • Speed boost is applied immediately.
Collectible Mom's Contacts iconMom's Contacts
  • Range and tears height buffs are applied immediately.
Collectible Steam Sale iconSteam Sale
  • Having multiple Steam Sales reduces all shop prices to 0 coins.
  • Causes the Deals with the Devil not to convert the heart type automatically.
Collectible The Virus iconThe Virus
  • Each poison hit deals damage equal to Isaac's tear damage instead of 4 or 6 damage.
  • Enemies killed after they have been inflicted with this type of poison have a 20% chance to drop black hearts.

Trinkets

Error: The given collectible ("Match Stick") does not exist.
  • Can replace the Tick.
Error: The given collectible ("Missing Poster") does not exist.
  • No longer displays a particular puzzle piece on the last will screen if Isaac dies in a Sacrifice Room while holding it.
  • Dying in a Sacrifice Room while holding it unlock The Lost, regardless of current character.
    • If The Lost was already unlocked, Isaac will be revived as The Lost and Missing Poster will be consumed.
    • If the player's character is already The Lost, he will be revived in the previous room and Missing Poster will be consumed.
Error: The given collectible ("Mysterious Paper") does not exist.
Error: The given collectible ("Tick") does not exist.

Interactions

Pickups

Bombs

Troll bomb
  • Troll Bombs are now given a random amount of time before exploding. Before that they always exploded at a fixed time. This means that if two Troll Bombs spawn at the exact same time right next to each other, there's a high chance one Troll Bomb will blow up before the other, sending that Troll Bomb sliding outwards a bit before exploding.

Entities

Monsters

Bony
  • Only leaves behind bones when killed.

Environment

Rooms

Boss Room
  • Double Trouble boss rooms can now contain 2 bosses of different types. Additionally, they can appear as early as Chapter 1.
Arcade
Angel Room
  • Possible rewards found in the room include:
  • Urns might spawn in the room.
  • Killing Key key master and shell game beggar no longer applies the 25% bonus.
  • Donating to a normal beggar until it pays out with an item on the current floor applies a 10% bonus instead of 25%.
  • Donating to a Devil beggar until it pays out with an item on the current floor applies a 10% bonus instead of 25%.
    • If this coin flip succeeds, a Devil Room will be generated regardless of the above coin flips.
  • "You feel blessed!" fortune in the Sacrifice Room of the current floor applies a bonus:
    • If the "You feel blessed!" fortune appeared on the 3rd sacrifice, the chance will be 15%.
    • If the "You feel blessed!" fortune appeared on the 5th sacrifice, the chance will be 50%.
    • If both "You feel blessed!" fortunes appeared, the chance will be 65%.
  • Angel Rooms that spawn after Isaac defeats Mom's Heart or It Lives will be normal Angel Rooms with items or pickups.
  • A troll bomb can sometimes appear behind the Angel Statue, blowing it up. If the Angel fights have been unlocked, this will begin the boss fight if the player is not careful or quick enough to move the bomb.
Bedroom
  • The clean bedroom occasionally has two clean beds instead of one.
  • The trapdoor in a dirty bedroom has a chance to lead to a Crawl Space.
  • Occasionally, one Rag Man will spawn inside the dirty bedroom.
Boss Rush

Boss Rush 2Boss Rush 3Boss Rush 4Boss Rush 5

  • If a sack spawns for whatever reason, picking it up will start the Boss Rush. The player can still pick up one of the pedestal items.
Black Market
  • Black Market can no longer be accessed in The Chest and The Dark Room, and therefore cannot be used to collect more items.
Treasure Room
  • There's a rare chance that a treasure room might contains two items to choose from, only one of which can be taken.
  • Treasure rooms may also contain a restock box, allowing Isaac to re-roll offered items if he has coins or bombs.
  • New layouts:

Treasure Room 13Treasure Room 14Treasure Room 15Treasure Room 16Treasure Room 17Treasure Room 18Treasure Room 19Treasure Room 20Treasure Room 21Treasure Room 22Treasure Room 23Treasure Room 26Treasure Room 27Treasure Room 28Treasure Room 31Treasure Room 32Treasure Room 33Treasure Room 34Treasure Room 35Treasure Room 36Treasure Room 37Treasure Room 38Treasure Room 39Treasure Room 24Treasure Room 30Treasure Room 25Treasure Room 29

Other

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