Editing The Binding of Isaac: Afterbirth

{{toc right}}{{context box | ana+ }}

'''''The Binding of Isaac: Afterbirth''''' is the expansion to ''[[The Binding of Isaac: Rebirth]]''. The DLC was released on October 30, 2015 and costs $10.99/£7.99. It was released on May 10, 2016 on Xbox One and PS4.

''For a list of the pre-release blog posts, see [[The Binding of Isaac: Afterbirth (Pre-Release)]].''

= Features =
* [[Greed Mode]]: A new game mode with a heavy focus on risk/reward, featuring a new [[ending]] and [[Ultra Greed|final boss]].
* [[Blue Womb]]: A new area, featuring a new [[ending]] and [[Hush|final boss]].
* [[Daily Challenges|Daily Runs]]: Daily seeded runs with online leaderboards.
* Two new characters, [[Lilith]] and [[Keeper]].
* 95 new [[Items#Afterbirth Collectibles|items]] and 29 new [[Trinkets#Afterbirth Trinkets|trinkets]].
* New [[pickups]], [[chests]], [[pills]], and [[Cards and Runes|cards]].
* 10 new [[challenges]].
* 4 new alternate chapters: [[Burning Basement]], [[Flooded Caves]], [[Dank Depths]], and [[Scarred Womb]].
* Many new room layouts including tiny rooms, long hallways, and L-shaped rooms.
* New room types like trap rooms, double treasure rooms, and [[closets]].
* New special [[seeds]], along with a seed code combo page.
* An expanded [[Music#The Binding of Isaac: Afterbirth|soundtrack]].
* An extra HUD option, allowing items picked up to be displayed on-screen.
* 9 new [[transformations]].
* New [[The Binding of Isaac: Afterbirth#Bosses|bosses]], along with new variations of bosses introduced in Rebirth.
* New [[The Binding of Isaac: Afterbirth#Monsters|monsters]].
* Updated item combo system.
* New [[Achievements#Afterbirth Achievements|achievements]].
* New [[Babies#Afterbirth Babies|co-op babies]].
* An improved [[Collection Page#Afterbirth Complete Collection Grid|collection page]] that shows item descriptions.

= Additions =
== Characters ==
{| style="border-spacing: 2px" cellpadding="4" data-description="Character Overview Table" width="24%"
|- style="text-align: center;vertical-align: bottom;background:#142e59"
! style="width: 8%" | Character 
! style="width: 8%" | [[File:Lilith App.png|82px|link=Lilith]] <br> [[Lilith]]
! style="width: 8%" | [[File:Keeper App.png|82px|link=Keeper]] <br> [[Keeper]]

|-style="text-align: center;background:#4a3026"
! [[File:Health Stat Icon.png|20px]] Health 
| {{RedHeart}}{{BlackHeart}}{{BlackHeart}} || {{CoinHeart}}{{CoinHeart}}

|-style="text-align: center;background:#4a3026"
! [[File:Damage Stat Icon.png|18px]] Damage 
| 3.5 (*1.00) || 3.5 (*1.20)

|-style="text-align: center;background:#4a3026"
! <span title="Difference from base tear rate" style="cursor:help">[[File:Tears Stat Icon.png|30px]] <span style="border-bottom: 1px dotted">Tears</span> </span>
| [[Blindfolded]] ||

|-style="text-align: center;background:#4a3026"
! [[File:Shot Speed Stat Icon.png|25px]] Shot Speed  
| [[Blindfolded]] || 1

|-style="text-align: center;background:#4a3026"
! [[File:Range Stat Icon.png|25px]] Range  
| [[Blindfolded]] || 23.75

|-style="text-align: center;background:#4a3026"
! [[File:Speed Stat Icon.png|25px]] Speed  
|  1.0 || 0.85

|-style="text-align: center;background:#4a3026"
! [[File:Luck Stat Icon.png|16px]] Luck 
| 0 || -2

|-style="text-align: center;background:#4a3026"
! [[File:Starting Item Icon.png|16px]] Starting Pickups 
| None || x1 [[Pickups#Bombs|Bombs]]<br>{{Unlockable}} x1 [[Pickups#Coins|Coins]]<br>{{Unlockable}} [[Store Key]]

|-style="text-align: center;background:#4a3026"
! [[File:Starting Item Icon.png|16px]] Starting Item(s) 
| [[Incubus]],<br>{{Unlockable}} [[Cambion Conception]],<br>[[Box of Friends]] || Triple shot,<br>{{Unlockable}} [[Wooden Nickel]]
|}

== Items ==
95 new items were added in the expansion: 19 activated items and 76 passive items.

=== Activated Collectibles ===
{{Table | Active |
{{Item|Box of Friends|table-nodlc}}
{{Item|D12|table-nodlc}}
{{Item|D7|table-nodlc}}
{{Item|D8|table-nodlc}}
{{Item|Diplopia|table-nodlc}}
{{Item|Friendly Ball|table-nodlc}}
{{Item|Glass Cannon|table-nodlc}}
{{Item|Glowing Hour Glass|table-nodlc}}
{{Item|Jar of Flies|table-nodlc}}
{{Item|Kidney Bean|table-nodlc}}
{{Item|Mega Bean|table-nodlc}}
{{Item|Mega Blast|table-nodlc}}
{{Item|Mine Crafter|table-nodlc}}
{{Item|Mom's Box|table-nodlc}}
{{Item|Placebo|table-nodlc}}
{{Item|Tear Detonator|table-nodlc}}
{{Item|Teleport 2.0|table-nodlc}}
{{Item|Ventricle Razor|table-nodlc}}
{{Item|Wooden Nickel|table-nodlc}}
}}

=== Passive Collectibles ===
{{Table | Passive |
{{Item|8 Inch Nails|table-nodlc}}
{{Item|Athame|table-nodlc}}
{{Item|Betrayal|table-nodlc}}
{{Item|Binky|table-nodlc}}
{{Item|Black Powder|table-nodlc}}
{{Item|Bomber Boy|table-nodlc}}
{{Item|Bumbo|table-nodlc}}
{{Item|Bursting Sack|table-nodlc}}
{{Item|Cambion Conception|table-nodlc}}
{{Item|Car Battery|table-nodlc}}
{{Item|Censer|table-nodlc}}
{{Item|Chaos|table-nodlc}}
{{Item|Charged Baby|table-nodlc}}
{{Item|Circle of Protection|table-nodlc}}
{{Item|Continuum|table-nodlc}}
{{Item|Crack Jacks|table-nodlc}}
{{Item|Crown of Light|table-nodlc}}
{{Item|Curse of the Tower|table-nodlc}}
{{Item|Dead Eye|table-nodlc}}
{{Item|Deep Pockets|table-nodlc}}
{{Item|Eden's Blessing|table-nodlc}}
{{Item|Empty Vessel|table-nodlc}}
{{Item|Epiphora|table-nodlc}}
{{Item|Evil Eye|table-nodlc}}
{{Item|Explosivo|table-nodlc}}
{{Item|Farting Baby|table-nodlc}}
{{Item|Fate's Reward|table-nodlc}}
{{Item|Friend Zone|table-nodlc}}
{{Item|Fruit Cake|table-nodlc}}
{{Item|GB Bug|table-nodlc}}
{{Item|Glitter Bombs|table-nodlc}}
{{Item|God's Flesh|table-nodlc}}
{{Item|Head of the Keeper|table-nodlc}}
{{Item|Holy Light|table-nodlc}}
{{Item|Host Hat|table-nodlc}}
{{Item|Immaculate Conception|table-nodlc}}
{{Item|Incubus|table-nodlc}}
{{Item|Key Bum|table-nodlc}}
{{Item|Kidney Stone|table-nodlc}}
{{Item|Lil' Chest|table-nodlc}}
{{Item|Lil Gurdy|table-nodlc}}
{{Item|Lil' Loki|table-nodlc}}
{{Item|Lost Fly|table-nodlc}}
{{Item|Lusty Blood|table-nodlc}}
{{Item|Marked|table-nodlc}}
{{Item|Maw of the Void|table-nodlc}}
{{Item|Milk!|table-nodlc}}
{{Item|Mom's Pearls|table-nodlc}}
{{Item|More Options|table-nodlc}}
{{Item|Mr. Dolly|table-nodlc}}
{{Item|Multidimensional Baby|table-nodlc}}
{{Item|My Shadow|table-nodlc}}
{{Item|Night Light|table-nodlc}}
{{Item|No. 2|table-nodlc}}
{{Item|Papa Fly|table-nodlc}}
{{Item|Pay to Play|table-nodlc}}
{{Item|PJs|table-nodlc}}
{{Item|Pupula Duplex|table-nodlc}}
{{Item|Purity|table-nodlc}}
{{Item|Obsessed Fan|table-nodlc}}
{{Item|Restock|table-nodlc}}
{{Item|Rune Bag|table-nodlc}}
{{Item|Sack Head|table-nodlc}}
{{Item|Scatter Bombs|table-nodlc}}
{{Item|Seraphim|table-nodlc}}
{{Item|Serpent's Kiss|table-nodlc}}
{{Item|Sticky Bombs|table-nodlc}}
{{Item|Spear of Destiny|table-nodlc}}
{{Item|Spider Mod|table-nodlc}}
{{Item|Succubus|table-nodlc}}
{{Item|Sworn Protector|table-nodlc}}
{{Item|Tech X|table-nodlc}}
{{Item|Toxic Shock|table-nodlc}}
{{Item|Tractor Beam|table-nodlc}}
{{Item|The Wiz|table-nodlc}}
{{Item|Zodiac|table-nodlc}}
}}

== Trinkets ==
29 new trinkets were added in the expansion.

{{Table | Trinket |
{{Item|Blasting Cap|table-nodlc}}
{{Item|Black Feather|table-nodlc}}
{{Item|Blind Rage|table-nodlc}}
{{Item|Blister|table-nodlc}}
{{Item|Brown Cap|table-nodlc}}
{{Item|Bob's Bladder|table-nodlc}}
{{Item|Child Leash|table-nodlc}}
{{Item|Cracked Dice|table-nodlc}}
{{Item|Endless Nameless|table-nodlc}}
{{Item|Error|table-nodlc}}
{{Item|Faded Polaroid|table-nodlc}}
{{Item|Golden Horse Shoe|table-nodlc}}
{{Item|Karma|table-nodlc}}
{{Item|Lazy Worm|table-nodlc}}
{{Item|Lil Larva|table-nodlc}}
{{Item|Louse|table-nodlc}}
{{Item|Mom's Locket|table-nodlc}}
{{Item|NO!|table-nodlc}}
{{Item|Poker Chip|table-nodlc}}
{{Item|Rainbow Worm|table-nodlc}}
{{Item|Rib of Greed|table-nodlc}}
{{Item|Safety Scissors|table-nodlc}}
{{Item|Second Hand|table-nodlc}}
{{Item|Shiny Rock|table-nodlc}}
{{Item|Store Key|table-nodlc}}
{{Item|Stud Finder|table-nodlc}}
{{Item|Super Magnet|table-nodlc}}
{{Item|Tape Worm|table-nodlc}}
{{Item|Watch Battery|table-nodlc}}
}}

== Pickups ==
=== Pickups & Chests ===
{| style="border-spacing:2px; width:100%" cellpadding="4" class="wikitable mw-collapsible"
|- style="text-align: center;vertical-align: bottom;background:#142e59"
! Name
! Icon
! Description
|-
| [[Hearts_(Pickup)#Gold Heart|Gold Heart]]
| [[File:GoldHeart.PNG|32px]]
| Gold Hearts are the rarest variation of a heart. They are unlocked by completing the challenge {{Afterbirth}}[[XXXXXXXXL]]. They always appear as full hearts and, once picked up, drop money the next time Isaac loses a Heart. A Golden Heart appends to the end of the health bar, surrounding it in a golden glow.
|-
| [[Coins_(Pickup)#Lucky Penny|Lucky Penny]]
| [[File:Coin.png|36px]]
| A Lucky Penny increases luck by 1 when picked up. Unlocked by donating 1 coin to the [[Greed Machine]]. [[Bumbo]] and [[Bum Friend]] are unable to pick up Lucky Pennies; they instead hover over them attempting to pick them up. [[Humbling Bundle]] does not double lucky pennies.
|-
| [[Coins_(Pickup)#Sticky Nickel|Sticky Nickel]]
| [[File:Nickel.png|36px]]
| A Nickel that will flip upside-down when Isaac tries to collect it. Afterwards, it will get stuck on the ground, unable to be picked up unless blasted off the ground with an explosion. Unlocked by completing [[Boss Rush]] with [[Keeper]]. It won't reduce the spawn rate of regular Nickels: rather, Pennies have an additional chance to become Sticky Nickels.
|-
| [[Bombs_(Pickup)#Gold Bombs|Gold Bombs]]
| [[File:Gold Bomb.png|40px]]
| Gold bombs will not add to the player's bomb count, but when picked up, they will give the player unlimited bombs for the duration of the current floor, similarly to [[Pickups#Golden Key|Golden Keys]]. They are unlocked by completing the challenge [[Blue Bomber]].
|-
| [[Chests#Angel Chests|Angel Chests]]
| [[File:AngelChest.png|60px]]
| Angel Chests are similar in appearance to Gold Chests, except they glow bright blue instead of gold, like a [[soul heart]]. They require one key to unlock, but can be reopened a random amount of times, each time requiring another key. They can be found in [[Angel Room|Angel rooms]] and rarely in a normal room. Their loot is similar to Golden Chests, but they can also drop nothing upon opening. If they contain nothing or an item, they will no longer be able to be reopened.
|-
| [[Chests#Spike Chests|Spike Chests]]
| [[File:SpikeChest.png|64px]]
| Spike Chests are purple colored chests with spikes protruding from them that will deal damage to Isaac upon opening (unless he has the [[Holy Mantle]] active, which nullifies the damage, or if found in [[The Chest]], where they are free to open). They can be rarely found upon completing a room or in greed mode shops. Their loot is similar to Brown Chests. Unlike other chests, they do not appear on the minimap. 
|-
| Mystery Sack
| [[File:MysteryBag.png|40px]]
| The Mystery Sack will spawn 1-4 pickups upon touching it. [[Sack Head]] greatly increases the chances of finding sacks.
|}

=== Pills ===
{| class="mw-collapsible wikitable striped" style="text-align:center; width:100%"
|style="background:#45264D;width:130px;font-size:10pt;color:#FFFFFF;font-weight:bold"|Pill
|style="background:#45264D;font-size:10pt;color:#FFFFFF;font-weight:bold"|Effect
|-
|{{Unlockable}} Addicted ||<p style="text-align: left;">Makes Isaac take a full heart of damage from all sources for the current room. Unlocked by completing Challenge #24: [[PAY TO PLAY]].</p>
|-
|Friends Till The End! ||<p style="text-align: left;">Spawns three [[Blue Flies]].</p>
|-
|Infested! ||<p style="text-align: left;">Destroys all [[Obstacles#Poop|poop]] in the room and spawns a single [[Blue Spider]] under Isaac and on each destroyed poop.</p>
|-
|Infested? ||<p style="text-align: left;">Spawns [[Blue Spider]]s equal to the number of enemies in the room. If there are no enemies in the room, spawns 1-3 Blue Spiders.</p>
|-
|One Makes You Small ||<p style="text-align: left;">Decreases Isaac's size and increases the pitch of his voice. This effect decreases the size of Isaac's hitbox.</p>
|-
|One Makes You Larger ||<p style="text-align: left;">Increases Isaac's size and decreases the pitch of his voice. This effect does not increase the size of Isaac's hitbox.</p>
|-
|{{Unlockable}} Percs ||<p style="text-align: left;">Gives [[The Wafer]] effect while in the room. Unlocked by completing Challenge #24: [[PAY TO PLAY]].</p>
|-
|Power Pill ||<p style="text-align: left;">Activates an effect similar to [[The Gamekid]].</p>
|-
|{{Unlockable}} Re-Lax ||<p style="text-align: left;">For a short time, poop spawns wherever Isaac moves, like Explosive Diarrhea but with poop. A higher move speed means you can touch more tiles in the same time. A pun on laxatives. Unlocked by completing Challenge #25: [[Have a Heart]].</p>
|-
|Retro Vision ||<p style="text-align: left;">Briefly pixelates the screen 3 times over 30 seconds.</p>
|-
|{{Unlockable}} ??? ||<p style="text-align: left;">Gives the Curse of the Maze effect for the remainder of the floor. The effect can stack with other [[Curses|curses]]. If no other [[Curses|curses]] are active for the floor, Curse of the Maze will appear under the level name when TAB is held. This effect cannot be negated by [[Black Candle]]. Unlocked by completing Challenge #25: [[Have a Heart]].</p>
|}

=== Cards & Runes ===
{{Table | Card |
{{Item|? Card|table-nodlc}}
{{Item|Get out of Jail Free Card|table-nodlc}}
{{Item|Emergency Contact|table-nodlc}}
{{Item|Dice Shard|table-nodlc}}
}}
{{Table | Rune |
{{Item|Blank Rune|table-nodlc}}
}}

==Transformations==
{| class="mw-collapsible wikitable" style="width:100%"
! style="width:40px" | Transformation
! style="width:100px" | Appearance
! style="width:200px" | Transformation effect
! style="width:100px" | Item
! style="width:50px" | Icon
! Item effect
! style="width:40px" | Recharge
|- style="border-top:2px solid black"
| rowspan="5" style="text-align:center" | [[Bob (Transformation)|Bob]]
| rowspan="5" | [[File:Bob_Transformation.png|100x100px|class=pixelimage]]
| rowspan="5" |
* Isaac gains a green trail of  [[effects#poison|poisonous]] [[creep]].
{{Item|Bob's Rotten Head|table-tr}}
{{Item|Bob's Brain|table-tr}}
{{Item|Bob's Curse|table-tr}}
{{Item|Ipecac|table-tr}}

|- style="border-top:2px solid black"
| rowspan="8" style="text-align:center" | [[Conjoined (Transformation)|Conjoined]]
| rowspan="8" | [[File:Baby_Transformation.png|100x100px|class=pixelimage]]
| rowspan="8" |
* When attacking, the tumor faces shoot tears diagonally outwards, similar to the effect of [[The Wiz]].
* -0.3 [[damage]].
* Slightly decreases [[Attributes#Tears|tears]].
{{Item|Brother Bobby|table-tr}}
{{Item|Harlequin Baby|table-tr}}
{{Item|Headless Baby|table-tr}}
{{Item|Little Steven|table-tr}}
{{Item|Mongo Baby|table-tr}}
{{Item|Rotten Baby|table-tr}}
{{Item|Sister Maggy|table-tr}}

|- style="border-top:2px solid black"
| rowspan="8" style="text-align:center" | [[Fun Guy (Transformation)|Fun Guy]]
| rowspan="8" | [[File:Mushroom_Transformation.png|100x100px|class=pixelimage]]
| rowspan="8" |
* +1 [[Attributes#Heart_containers|heart container]].
{{Item|God's Flesh|table-tr}}
{{Item|Mini Mush|table-tr}}
{{Item|Magic Mushroom|table-tr}}
{{Item|Odd Mushroom (Thin)|table-tr}}
{{Item|Odd Mushroom (Large)|table-tr}}
{{Item|1up!|table-tr}}
{{Item|Blue Cap|table-tr}}

|- style="border-top:2px solid black"
| rowspan="10" style="text-align:center" | [[Leviathan (Transformation)|Leviathan]]
| rowspan="10" | [[File:Evil_Angel_Transformation.png|100x100px|class=pixelimage]]
| rowspan="10" |
* [[Flight]].
* +2 [[black heart]]s.
{{Item|The Nail|table-tr}}
{{Item|The Mark|table-tr}}
{{Item|Missing Page 2|table-tr}}
{{Item|The Pact|table-tr}}
{{Item|Pentagram|table-tr}}
{{Item|Spirit of the Night|table-tr}}
{{Item|Maw of the Void|table-tr}}
{{Item|Abaddon|table-tr}}
{{Item|Brimstone|table-tr}}

|- style="border-top:2px solid black"
| rowspan="4" style="text-align:center" | [[Oh Crap (Transformation)|Oh Crap]]
| rowspan="4" | [[File:Poop_Transformation.png|100x100px|class=pixelimage]]
| rowspan="4" |
* Whenever a pile of [[Obstacles#Poop|poop]] is destroyed, [[Attributes#Heart_containers|health]] is replenished by half a heart.
{{Item|Flush!|table-tr}}
{{Item|The Poop|table-tr}}
{{Item|E Coli|table-tr}}

|- style="border-top:2px solid black"
| rowspan="10" style="text-align:center" | [[Seraphim (Transformation)|Seraphim]]
| rowspan="10" | [[File:Angel_Transformation.png|100x100px|class=pixelimage]]
| rowspan="10" |
* [[Flight]].
* +3 [[soul heart]]s.
{{Item|The Bible|table-tr}}
{{Item|Dead Dove|table-tr}}
{{Item|Guardian Angel|table-tr}}
{{Item|Holy Grail|table-tr}}
{{Item|Holy Mantle|table-tr}}
{{Item|Mitre|table-tr}}
{{Item|Rosary|table-tr}}
{{Item|Sworn Protector|table-tr}}
{{Item|The Halo|table-tr}}

|- style="border-top:2px solid black"
| rowspan="9" style="text-align:center" | [[Spun (Transformation)|Spun]]
| rowspan="9" | [[File:Drugs_Transformation.png|100x100px|class=pixelimage]]
| rowspan="9" |
* +2 [[Attributes#Damage|damage]].
* +0.15 [[Attributes#Speed|speed]].
* Spawns a random [[pill]] upon transformation.
{{Item|Adrenaline|table-tr}}
{{Item|Euthanasia|table-tr}}
{{Item|Experimental Treatment|table-tr}}
{{Item|Growth Hormones|table-tr}}
{{Item|Roid Rage|table-tr}}
{{Item|Speed Ball|table-tr}}
{{Item|Synthoil|table-tr}}
{{Item|The Virus|table-tr}}

|- style="border-top:2px solid black"
| rowspan="18" style="text-align:center" | [[Yes Mother (Transformation)|Yes, Mother?]]
| rowspan="18" | [[File:Mom_Transformation.png|100x100px|class=pixelimage]]
| rowspan="18" |
* Isaac gains a stationary knife that trails directly behind him. It synergizes like [[Mom's Knife]] would.
{{Item|Mom's Bottle of Pills|table-tr}}
{{Item|Mom's Bra|table-tr}}
{{Item|Mom's Pad|table-tr}}
{{Item|Mom's Wig|table-tr}}
{{Item|Mom's Eye|table-tr}}
{{Item|Mom's Purse|table-tr}}
{{Item|Mom's Contacts|table-tr}}
{{Item|Mom's Knife|table-tr}}
{{Item|Mom's Heels|table-tr}}
{{Item|Mom's Eyeshadow|table-tr}}
{{Item|Mom's Perfume|table-tr}}
{{Item|Mom's Key|table-tr}}
{{Item|Mom's Lipstick|table-tr}}
{{Item|Mom's Underwear|table-tr}}
{{Item|Mom's Coin Purse|table-tr}}
{{Item|Mom's Pearls|table-tr}}
{{Item|Mom's Razor|table-tr}}

|- style="border-top:2px solid black"
| rowspan="4" style="text-align:center" | [[Super Bum (Transformation)|Super Bum]]
| rowspan="4" | [[File:Super Bum.png|100x100px|class=pixelimage]]<br><sup>1</sup>
| rowspan="4" |
* Replaces [[Bum Friend]], [[Dark Bum]], and [[Key Bum]] for [[Super Bum (Transformation)|Super Bum]].<br/> He collects any of the other beggars' pickups, and offers twice the rewards.
{{Item|Bum Friend|table-tr}}
{{Item|Dark Bum|table-tr}}
{{Item|Key Bum|table-tr}}
|}
:<sup>1: Image depicts the familiar. This transformation does not alter Isaac's appearance.</sup>

== NPCs ==
=== Monsters ===
Many new monsters were added in the expansion. Additionally, several new [[Monsters#Champions|champion]] types were added.

{| class="wikitable mw-collapsible"
! Monster
! Description
|-
{{Monster|Dart Fly|table-nodlc}}
{{Monster|Swarm Fly|table-nodlc}}
{{Monster|Drowned Boom Fly|table-nodlc}}
{{Monster|Corn Dip|table-nodlc}}
{{Monster|Dank Squirt|table-nodlc}}
{{Monster|Roundy|table-nodlc}}
{{Monster|Ulcer|table-nodlc}}
{{Monster|Drowned Hive|table-nodlc}}
{{Monster|Dukie|table-nodlc}}
{{Monster|Flaming Gaper|table-nodlc}}
{{Monster|Cyclopia|table-nodlc}}
{{Monster|Black Bony|table-nodlc}}
{{Monster|Dank Death's Head|table-nodlc}}
{{Monster|Flesh Death's Head|table-nodlc}}
{{Monster|Fat Bat|table-nodlc}}
{{Monster|Red Ghost|table-nodlc}}
{{Monster|Flaming Fatty|table-nodlc}}
{{Monster|Conjoined Fatty|table-nodlc}}
{{Monster|Blue Conjoined Fatty|table-nodlc}}
{{Monster|Dank Globin|table-nodlc}}
{{Monster|Black Globin|table-nodlc}}
{{Monster|Black Globin's Body|table-nodlc}}
{{Monster|Bone Knight|table-nodlc}}
{{Monster|Mega Clotty|table-nodlc}}
{{Monster|Mom's Dead Hand|table-nodlc}}
{{Monster|Drowned Charger|table-nodlc}}
{{Monster|Scarred Para-Bite|table-nodlc}}
{{Monster|Scarred Guts|table-nodlc}}
{{Monster|Scarred Double Vis|table-nodlc}}
{{Monster|Meatball|table-nodlc}}
{{Monster|Imp|table-nodlc}}
{{Monster|Greed Gaper|table-nodlc}}
{{Monster|Blue Gaper|table-nodlc}}
{{Monster|Blue Boil|table-nodlc}}
{{Monster|Hush Fly|table-nodlc}}
|}

=== Bosses ===
Several new bosses were added in the expansion. Additionally, many bosses received new champion variants.
{| style="width:70%; align:left padding-right:2em"
| style="text-align: center;" |[[File:Boss_Rag_Man.png|center|link=Rag Man]]
| style="text-align: center;" |[[File:Boss_Little_Horn.png|center|link=Little Horn]]
| style="text-align: center;" |[[File:Boss_Dangle.png|center|link=Dangle]]
| style="text-align: center;" |[[File:Boss_Turdlings.png|center|link=Turdlings]]
|-
| style="text-align: center;" |[[Rag Man]]
| style="text-align: center;" |[[Little Horn]] 
| style="text-align: center;" |[[Dangle]]
| style="text-align: center;" |[[Turdlings]]
|}
{| style="width:70%; align:left padding-right:2em"
| style="text-align: center;" |[[File:Boss_The_Frail.png|center|link=The Frail]]
| style="text-align: center;" |[[File:Boss_The_Stain.png|center|link=The Stain]]
| style="text-align: center;" |[[File:Boss_The_Forsaken.png|center|link=The Forsaken]]
| style="text-align: center;" |[[File:Boss_Brownie.png|center|link=Brownie]]
|-
| style="text-align: center;" |[[The Frail]]
| style="text-align: center;" |[[The Stain]]
| style="text-align: center;" |[[The Forsaken]]
| style="text-align: center;" |[[Brownie]]
|}

{| style="width:70%; align:left padding-right:2em"
| style="text-align: center;" |[[File:Boss_Hush.png|center|link=Hush]]
| style="text-align: center;" |[[File:Boss_Ultra_Greed.png|center|link=Ultra Greed]]
|-
| style="text-align: center;" |[[Hush]]
| style="text-align: center;" |[[Ultra Greed]]
|}

=== Beggars ===
; [[File:Bomb bum.png|60px]] [[Bomb Bum]]
Bomb Bums are extremely rare, and ask for bombs. Each bomb donated has a chance to have him drop 1-2 bomb pickups or an item from the Bomb Bum Item Pool. After spawning a pedestal item, the Bomb Bum will disappear and can no longer be donated to.

== Environment ==
=== Chapters ===
{| style="width:80%; align:left padding-right:2em"
| style="text-align: center;" |[[File:Burning_Basement.png|350px|link=Burning Basement]]
| style="text-align: center;" |[[File:Flooded Caves.png|350px|link=Flooded Caves]]
|-
| style="text-align: center;" | [[Burning Basement]]
| style="text-align: center;" | [[Flooded Caves]]
|-
| style="text-align: center;" |[[File:Dank_Depths.png|350px|link=Dank Depths]]
| style="text-align: center;" |[[File:Scarred Womb.png|350px|link=Scarred Womb|]]
|-
| style="text-align: center;" | [[Dank Depths]]
| style="text-align: center;" | [[Scarred Womb]]
|-
| style="text-align: center;" colspan="2" |[[File:Blue Womb.png|350px|link=Blue Womb]]
|-
| style="text-align: center;" colspan="2" | ??? ([[Blue Womb]])
|}

== Challenges ==
{| class="wikitable mw-collapsible sortable striped" style="text-align:left; width:100%; height:100%"
! Name
! Conditions
! Goal
! Unlocked by
! class="unsortable" | Unlocks
{{Chlg|XXXXXXXXL|table-nodlc}}
{{Chlg|SPEED!|table-nodlc}}
{{Chlg|Blue Bomber|table-nodlc}}
{{Chlg|PAY TO PLAY|table-nodlc}}
{{Chlg|Have a Heart|table-nodlc}}
{{Chlg|I RULE!|table-nodlc}}
{{Chlg|BRAINS!|table-nodlc}}
{{Chlg|PRIDE DAY!|table-nodlc}}
{{Chlg|Onan's Streak|table-nodlc}}
{{Chlg|The Guardian|table-nodlc}}
|}

= Changes =
== Items ==
=== Activated Collectibles ===
; [[Book of Revelations]]
Increases chance for a Devil/Angel Room Door to open by 17.5%.

=== Passive Collectibles ===
; [[20/20]]
* [[File:20 20 Afterbirth Icon.png]] Its icon is white-tinted.
; [[3 Dollar Bill]]
* The type of randomized tear changes every 2-3 seconds. The item appears to select two tear effects at once, perhaps staggering the times at which each of those effects change.
* If a run is quit, and then continued, 3 Dollar Bill will keep tear effects for the current room.
; [[Abel]]
* Abel shoots tears towards Isaac regardless of which direction Isaac is shooting.
; [[Ball of Bandages]]
* Ball of Bandages blocks enemy shots.
; [[Bob's Brain]]
* Bob's Brain is fired directly from where it is located in the chain of familiars behind Isaac, making aiming it slightly more difficult.
; [[Bomb Bag]]
* Can drop a [[Gold Bomb]].
; [[Box]]
* Can drop a Gold Bomb.

=== Interactions ===
{{Scroll box | height = 400px | content =
* [[20/20]] + [[Brimstone]] - Two brimstone shots are fired, without an increase in charge time.
* [[20/20]] + [[Epic Fetus]] - Makes two missiles drop one after the other.
* [[20/20]] + [[The Inner Eye]] - 5 shots are fired with the normal decrease in fire rate.
* [[20/20]] + [[Mom's Knife]] - Two knives are now thrown instead of one.
* [[20/20]] + [[Mutant Spider]] - 6 shots are fired with the normal decrease in fire rate.
* [[20/20]] + [[Technology]] - Two technology shots are fired simultaneously.
* [[20/20]] + [[Tractor Beam]]-  Both tears are fired along the beam although due to a bug the second tear in each pair is invisible.
* [[20/20]] + [[The Wiz]] - Two tears are fired each direction.
* [[9 Volt]] + [[Wooden Nickel]] - Infinite coins (if you have the time).
* [[A Card Against Humanity]] + [[Brown Cap]] - All the poop explodes in a chain reaction once one is destroyed.
* [[A Card Against Humanity]] + [[Pills|Infested!]] - Every pile of poop spawns a blue spider.
* [[A Card Against Humanity]] + [[Lil Larva]] - Every pile of poop spawns a blue Fly.
* [[A Lump of Coal]] + [[Athame]] - Damage of the Athame ring is halved.
* [[A Lump of Coal]] + [[Brimstone]] + Beam will gradually increase in size and damage the farther it travels, on a multiplier that is roughly +20% per tile of distance.
* [[A Lump of Coal]] + [[Maw of the Void]] - Damage of the Maw ring is halved.
* [[A Lump of Coal]] + [[Tape Worm]] - The significant range up increases Coal's damage potential, despite the shot height being halved.
* [[A Lump of Coal]] + [[Technology]] - Damage increases the further away the enemy is, on a multiplier that is roughly +20% per tile of distance.
* [[A Lump of Coal]] + [[Technology 2]] - Damage increases the further away the enemy is, on a multiplier that is roughly +20% per tile of distance.
* [[A Lump of Coal]] + [[Tech X]] - Ring size and damage increases as ring travels further from Isaac.
* [[Anarchist Cookbook]] + [[Blasting Cap]] - The troll bombs have a chance to drop bomb pickups upon exploding.
* [[Anarchist Cookbook]] + [[Bob's Bladder]] - The troll bombs will leave [[green creep]].
* [[Anarchist Cookbook]] + [[Bomber Boy]] - The troll bombs will explode in a shape of a cross, making them very powerful but hard to dodge.
* [[Anarchist Cookbook]] + [[Glitter Bombs]] - Each troll bomb has a chance to drop a [[pickup]].
* [[Anarchist Cookbook]] + [[Scatter Bombs]] - Each troll bomb will spawn several smaller bombs upon exploding.
* [[Anarchist Cookbook]] + [[Safety Scissors]] - The troll bombs will all be defused and turn into [[Pickups#Bombs|bomb pickups]].
* [[Anarchist Cookbook]] + [[Sticky Bombs]] - If a troll bomb kills a enemy, it will spawn blue spiders.
* [[Anti-Gravity]] + [[Multidimensional Baby]] - Any moving tears that hit it will produce a normal moving copy, however stationary tears will spawn a stationary copy that will eventually fall to the ground even after the direction is released, allowing you to create a virtual minefield of tears while still using ranged tears as before. In addition, since the baby follows Isaac's path, it will automatically hit every tear you leave for as long as a direction is held.
* [[BBF]] + [[Brimstone]] - BBF will fire brimstone beams in all directions upon exploding.
* [[BFFS!]] + [[Fart Baby]] - The baby's increased size will make it easier to trigger the Baby's effect.
* [[BFFS!]] + [[Incubus]] - Incubus deals double your damage instead of copying it. Effectively doubles [[Lilith]]'s damage.
}}

== Pickups ==
=== Bombs ===
; [[Troll Bombs]]
* Troll Bombs are now given a random amount of time before exploding. Before that they always exploded at a fixed time. This means that if two Troll Bombs spawn at the exact same time right next to each other, there's a high chance one Troll Bomb will blow up before the other, sending that Troll Bomb sliding outwards a bit before exploding.

== NPCs ==
=== Monsters ===
; [[Bony]]
* They only leave behind bones when killed.

== Environment ==
=== Rooms ===
; [[Boss Room]]
* Double Trouble boss rooms can now contain 2 bosses of different types. Additionally, they can appear as early as [[Chapter 1]].
* [[Hush]] is always fought in a 2x2 room and [[Ultra Greed]] is fought in a double-sized one (2x1).

; [[Arcade]]
* An Arcade can contain a [[Bedroom|bed]], a [[key master]] and 3 hanging dead [[shopkeeper]]s.

; [[Angel Room]]
* Possible rewards found in the room include:
** 2 [[angel chest]]s
** 1 [[eternal heart]], and 4 [[soul heart]]s behind [[key block]]s
** {{GreedMode}} 6 coins
** {{GreedMode}} 2 [[soul heart]]s and 1 [[gold heart]].
* [[Urn]]s might spawn in the room.
* Killing Key [[key master]] and [[shell game beggar]] no longer applies the 25% bonus.
* Donating to a [[normal beggar]] until it pays out with an item on the current floor applies a 10% bonus instead of 25%.
* Donating to a [[Devil beggar]] until it pays out with an item on the current floor applies a 10% bonus instead of 25%.
** If this coin flip succeeds, a Devil Room will be generated regardless of the above coin flips.
* "You feel blessed!" fortune in the [[Sacrifice Room]] of the current floor applies a bonus:
** If the "You feel blessed!" fortune appeared on the 3rd sacrifice, the chance will be 15%.
** If the "You feel blessed!" fortune appeared on the 5th sacrifice, the chance will be 50%.
** If both "You feel blessed!" fortunes appeared, the chance will be 65%.
* Angel Rooms that spawn after Isaac defeats Mom's Heart or It Lives will be normal Angel Rooms with items or pickups.
* A [[troll bomb]] can sometimes appear behind the Angel Statue, blowing it up. If the Angel fights have been unlocked, this will begin the boss fight if the player is not careful or quick enough to move the bomb.

; [[Bedroom]]
* The clean bedroom occasionally has two clean beds instead of one.
* The trapdoor in a dirty bedroom has a chance to lead to a Crawl Space.
* Occasionally, one [[Rag Man]] will spawn inside the dirty bedroom.

; [[Boss Rush]]
* There is a chance that there will only be 2 items to choose from. Additionally, items may be trapped behind [[Obstacles#Rocks|rocks]] or [[Obstacles#Spikes|spikes]]. Items may appear in the corners of the room instead of the center.
* All 15 waves are randomized. Each wave spawns two random bosses from the list. Each boss can only appear once per Boss Rush.
** [[Brownie]], [[Dangle]], [[Dark One]], [[Dingle]], 3x [[Gurglings]], [[Little Horn]], [[Mega Fatty]], [[Mega Maw]], [[Polycephalus]], [[Rag Man]], [[The Adversary]], [[The Cage]], [[The Forsaken]], [[The Frail]], [[The Gate]], [[The Haunt]], [[The Stain]], and 3x [[Turdlings]] can appear in the Boss Rush.
** The angels [[Uriel]] and [[Gabriel]] can also appear.
* New layouts:
[[File:Boss_Rush_2.png|200px]][[File:Boss_Rush_3.png|200px]][[File:Boss_Rush_4.png|200px]][[File:Boss_Rush_5.png|200px]]
* If a [[Pickups#Mystery Sack|sack]] spawns for whatever reason, picking it up will start the Boss Rush. The player can still pick up one of the pedestal items.

; [[Black Market]]
* Black Market can no longer be accessed in The Chest and The Dark Room, and therefore cannot be used to collect more items.

== Other ==
* When not having red hearts in [[Devil Room]], the price of items switches to soul hearts.
* [[Krampus]] has a new attack pattern.
* [[The Lost]] is now unlocked by dying in a [[Sacrifice Room]] while holding [[Missing Poster]].
* Sacrifice rooms were reworked to give more useful rewards.

= Gallery =
<gallery>
Afterbirth Title Screen.png|The title screen of The Binding of Isaac: Afterbirth.
</gallery>

= Trivia =
* [[wikipedia:Placental expulsion|Afterbirth]] is the placenta and fetal membranes discharged from the uterus after the birth of offspring, which might be why the title screen is bloody.

{{nav|version}}
[[Category:Afterbirth]]