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The Common Cold

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Item icon
Item altar
 
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Character appearance
 
Tear appearance
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Treasure Room Treasure Room
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Added in Afterbirth(page 1, column 20, row 5)
Removed in Afterbirth(page 1, column 10, row 10)

The Common Cold is a passive item.

Effects[edit | edit source]

  • Adds a chance to shoot poison tears, dealing damage over time when inflicted.
  • The poison randomly hits either 2 or 3 times, dealing a total of 4 or 6 damage.
    • Added in Afterbirth The poison hits twice, dealing a total of double Isaac's damage.

Notes[edit | edit source]

  • The chance for a tear to be poisoned depends on the Luck stat, and goes up to 100% at 12 Luck.
  • Unlike Scorpio ScorpioScorpio Icon.pngGrants poison tears, which deal damage over time when inflicted., The Common Cold will only inflict poison status when a poison tear is triggered and is therefore strictly inferior.

Synergies[edit | edit source]

  • 20/20 20/2020 20 Icon.pngGrants double shot./The Inner Eye The Inner EyeThe Inner Eye Icon.pngGrants triple shot but decreases tears./Mutant Spider Mutant SpiderMutant Spider Icon.pngGrants quadruple shot but decreases tears.: Increased chances for tears to be poisonous.
  • Brimstone BrimstoneBrimstone Icon.pngTears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.: The laser turns green and the poison effect sometimes applies to enemies.
  • Added in Afterbirth †Compound Fracture Compound FractureCompound Fracture Icon.pngIncreases range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle./Cricket's Body Cricket's BodyCricket's Body Icon.pngGrants -1 Tear Delay and reduces Range. When tears hit an object or deplete their range, they spawn 4 smaller tears, whose Range and Damage scale with Isaac's./Added in Afterbirth †Haemolacria HaemolacriaHaemolacria Icon.pngTears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay./The Parasite The ParasiteThe Parasite Icon.pngIsaac's tears split in two when they hit something.: Chance for tears and split tears to be poisonous. If the main tear is poisonous, the split tears are too.
  • Dr. Fetus Dr. FetusDr. Fetus Icon.pngTears are replaced by bombs that benefit from bomb-enhancing effects and slide for a fixed time after being fired./Epic Fetus Epic FetusEpic Fetus Icon.pngIsaac's tears are replaced with guided missiles, like those used by the Doctor's Remote.: Chance for bombs/explosions to become poisonous like Bob's Curse Bob's CurseBob's Curse Icon.pngGives 5 bombs and grants all bombs poison effect..
  • Added in Afterbirth †Lachryphagy LachryphagyLachryphagy Icon.pngIsaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage.: If a poison tear is fed, all burst tears are poisonous. If a normal tear is fed, the burst tears are not poisonous.
  • The Ludovico Technique The Ludovico TechniqueThe Ludovico Technique Icon.pngInstead of firing tears, Isaac controls one floating tear that hover over obstacles. This tear deals constant damage when held in place over an enemy.: Tear occasionally becomes green and can poison enemies.
  • Mom's Knife Mom's KnifeMom's Knife Icon.pngIsaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.: Poison effect applies sometimes.
  • Monstro's Lung Monstro's LungMonstro's Lung Icon.pngIncreases damage and grants a charged shot that fires multiple tears in the same fashion as Monstro.: Some of the tears in the tears cluster will be poisonous.
  • Technology TechnologyTechnology Icon.pngReplaces tears with a piercing laser with unlimited range.: The laser is green and the poison effect sometimes applies to enemies.


Interactions[edit | edit source]

  • Ipecac IpecacIpecac Icon.pngReplaces tears with explosive and poisoning projectiles fired in an arc from the mouth./Scorpio ScorpioScorpio Icon.pngGrants poison tears, which deal damage over time when inflicted.: Overrides The Common Cold.

In-game Footage[edit | edit source]

Seeds[edit | edit source]

PC[edit | edit source]

 PC  ANX3 VC3V (Adjacent Treasure Room)

 PC  Added in Afterbirth Hard mode only MPLX AJVP (Treasure Room adjacent to spawn ; Curse of the Labyrinth)

Switch[edit | edit source]

 Switch  Normal mode only KWFP J9MK (First Floor Treasure Room ; East from Start)


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