| Holy GrailGrants flight and one heart container.|
Isaac's HeartIsaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt.
Punching BagSpawns a Mulligan Familiar that will wander the room randomly. Enemies will attack the Mulligan if it's closer.
Spear of DestinyIn addition to tears, Isaac now holds a spear in front of him which deals damage equal to 2 times his tear damage, and occasionally inflicts fear. The spear cannot be thrown, but deals damage while it is in contact with an enemy.
|: no : yes|
|Blank RuneComplete challenge #30 ( The unlock is bugged and actually unlocks Kidney Stone)|
|Defeat Mom for the 1st timeThe Guardian|
The Guardian is a new challenge added in The Binding of Isaac: Afterbirth. Isaac starts blindfolded, with Punching BagSpawns a Mulligan Familiar that will wander the room randomly. Enemies will attack the Mulligan if it's closer., Isaac's HeartIsaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt., Holy GrailGrants flight and one heart container., and Spear of DestinyIn addition to tears, Isaac now holds a spear in front of him which deals damage equal to 2 times his tear damage, and occasionally inflicts fear. The spear cannot be thrown, but deals damage while it is in contact with an enemy.. The goal is to defeat Mom's Heart or It Lives. Isaac's Heart will follow the Punching Bag instead of Isaac.
Difficulty[edit | edit source]
The main difficulty of this challenge stems from the fact that Isaac's health is damaged when the Punching Bag is hit for any reason (due to Isaac's Heart), and that the Punching Bag will move of its own unpredictable accord, severely hindering the player's agency in avoiding damage. This makes The Guardian one of the tougher challenges in the game.
Note since it's the Punching Bag who takes damage, and it doesn't have flight, the Punching Bag is not immune to spikes and creep as Isaac's Heart would be. The lack of Treasure Rooms and tears only further compounds to the difficulty, to the point where certain rooms and bosses, which can be normally completed without taking damage, may now guarantee substantial amount of unavoidable damage. For example, Red Champion Mom is almost impossible to clear as she will always target Punching Bag.
Strategy[edit | edit source]
- The player should follow a general priority in which enemies to kill: enemies that run towards the Punching Bag, followed by exploding enemies, followed by enemies with piercing shots (i.e. Enemies that fire BrimstoneTears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period. shots), followed by enemies that fire regular shots. Remember that Isaac himself is invincible, allowing him to "body-block" shots flying towards the heart.
- Rooms containing Mom's Hand are almost impossible to clear (because the Punching Bag is incapable of dodging them), and should be skipped whenever possible. Bombs can be used to skip these rooms by bombing doors open.
- It may be better to go for Angel Rooms rather than Devil Rooms in this challenge, since they may offer invaluable items like The BibleUpon activation, Isaac gains flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but will kill Isaac when activated while fighting Satan., The WaferAll sources of damage that would cause more than one half heart of damage are reduced to one half heart instead., and Breath of LifeGrants a brief moment of invincibility when the charge bar hits zero. If spacebar is held for an additional second after hitting zero, Isaac will take damage. at the cost of no health.
- Finding or buying The Bible makes the challenge a lot easier, allowing Isaac to instantly kill both Mom and Mom's Heart.
- As the red champion version of Mom is nearly impossible to get past normally, a lot of health, The Wafer, or Chaos CardThrows the card to kill anything in its path. Opens normal doors. are necessary if Isaac doesn't have The Bible (or if it isn't fully recharged).
- Spend as little time as possible in rooms with spikes, because there's a high chance the Punching Bag will walk into them.
- Orbitals are extremely useful for this challenge, since most of them deal a good amount of damage on direct contact. Items such as Sacrificial DaggerDagger orbits Isaac, dealing very high damage. are the best source of damage. Health is also important to make up for unnecessary damage, as is Speed to rush towards enemies and destroy them before they can attack Isaac's Heart. Also, pick up the Humbling BundleGives one extra pickup (1+1 Free version) of Red Hearts, pennies, bombs, and keys. Does not work with blue, black, and half red hearts, nickels, and dimes. for its double Red Hearts.
- Isaac can use the spear's fear effect to his advantage and force bosses and mini-bosses away from Punching Bag. This is especially effective against bosses that chase Punching Bag, such as Gemini or Lust.
- It is possible to enter Boss Rush in this challenge. It’s not recommended to complete Boss Rush as it is very difficult without a strong set of items, but if Isaac finds any means to escape (e.g. 0 - The Fool), trying to beat Mom in under 20 minutes can be beneficial.
- If the player are not too concerned with time or score and just want the unlock, PlacentaGrants a full heart container, and a chance to regenerate a half-heart of health every minute of gameplay. is a good item to get as well since it can regenerate Isaac's health. A much, much slower way can be done by obtaining Mysterious CandyIsaac farts or poops at random intervals. Getting hit can also trigger the effect., which randomly spawns Poops. Destroying poop can drop half red hearts and soul hearts.
- The Breath of Life can be extremely helpful in completing this challenge. Isaac's Heart will enable the spacebar indefinitely and not take damage, while doing so will make Isaac completely immune to damage. He still can be hurt while the charge bar is still depleting after entering the room, but it does make things easier, especially with bosses, and allows him to explore rooms with hazards such as spikes without having to worry that the Punching Bag will wander into them.
- It should be noted that Isaac can transform into Guppy during this challenge even though the visual change that accompanies the transformation are not shown, and he will be able to make flies. The Spear of Destiny does not generate flies, but familiars and items that generate tears, such as Tammy's HeadShoots 10 tears in a circle around Isaac, which retain the damage, shot speed, and special effects (such as poison) of Isaac's tears. and IncubusA demonic familiar that follows Isaac and shoots tears identical to Isaac's in terms of damage, range, fire rate, and effects., will.
- Obtaining Blood RightsDamages all enemies in the room, but deals a heart of damage to Isaac with each use. basically wins the challenge as it can be spammed while annihilating everything inside (with the exception of Hosts and Cod Worms). But since there are no Treasure Rooms present, it can only be obtained via a lucky Crawl Space or room generation.
- Having a second player join in makes the game significantly easier. A co-op baby has its own Spear of Destiny and is not blindfolded so is able to shoot tears as normal. The co-op baby doesn't take damage because of Isaac's Heart.
- Obtaining AthameWhenever Isaac takes damage, a black ring briefly appears around Isaac, dealing damage to all nearby enemies. allows Isaac to activate the black brimstone ring without taking damage, which would make cleaning a room a lot easier, and spawn more black hearts.
- Obtaining The VirusInflicts poison to enemies who make contact with Isaac. Speed down. allows Isaac to inflict poison upon enemies without taking damage and get black hearts sometimes after killing enemies.
- Familiars such as Lil' BrimstoneA Familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting., The RelicIsaac is followed by a small blue cross that will drop a Soul Heart every 4 rooms., Dark BumSpawns a familiar that follows Isaac around and collects red hearts. For every one-and-a-half red hearts collected, Dark Bum will generate one soul heart, one hostile Spider or one friendly blue spider., Little C.H.A.D.A familiar who will drop a half red heart every 2 rooms., Incubus, and SuccubusSpawns a flying familiar that bounces around the room with a black aura, dealing rapid damage to any enemies inside it. While standing in the aura, Isaac gains a 1.5x tear damage multiplier. (especially when combined with BFFS!Increases the size and damage of familiars.) will make the challenge easier.
- One Makes You Small pills can make the challenge much more difficult, as the decreased hitbox makes it harder to block the Punching BagSpawns a Mulligan Familiar that will wander the room randomly. Enemies will attack the Mulligan if it's closer. from attacks.
- Book of ShadowsUpon use, creates a protective shield nullifying all types of damage for 10 seconds. also makes the challenge significantly easier as it can be activated in order to prevent Isaac's HeartIsaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt. from taking any damage for 10 seconds.
- Because of Isaac's Heart, he can enter curse rooms without taking damage.
- In curse rooms can find and use the Sacrificial AltarUpon use, sacrifices up to 2 familiars and spawns an item from the Devil Room Pool for each familiar sacrificed. to sacrifice both Punching Bag and Isaac's Heart, which could make the challenge easier.
- Duct TapeStops Isaac's familiars from moving. also makes the challenge harder, as Isaac's Heart will follow Isaac instead, resulting in two hitboxes.
- IpecacReplaces tears with explosive and poisoning projectiles fired in an arc from the mouth. can be extremely powerful because of its massive damage boost and poison effect.
Reward[edit | edit source]
|The WombDefeat Mom for the 1st timeThe HarbingersDefeat Mom for the 1st timeA Cube of MeatDefeat Mom for the 1st timeA HaloDefeat Mom using The BiblePuristDefeat Mom for the first time||XXXXXXXXLDefeat Mom for the 1st timeSPEED!Defeat Mom for the 1st timeHave a HeartDefeat Mom for the 1st timePRIDE DAY!Defeat Mom for the 1st timeOnan's StreakDefeat Mom for the 1st timeThe GuardianDefeat Mom for the 1st time||Aprils foolDefeat Mom for the 1st time|
|1.||Pitch Black||2.||High Brow||3.||Head Trauma||4.||Darkness Falls||5.||The Tank||6.||Solar System||7.||Suicide King||8.||Cat Got Your Tongue|
|9.||Demo Man||10.||Cursed!||11.||Glass Cannon||12.||When Life Gives You Lemons||13.||Beans!||14.||It's in the Cards||15.||Slow Roll||16.||Computer Savvy|
|17.||Waka Waka||18.||The Host||19.||The Family Man||20.||Purist|
|21.||XXXXXXXXL||22.||SPEED!||23.||Blue Bomber||24.||PAY TO PLAY||25.||Have a Heart||26.||I RULE!||27.||BRAINS!||28.||PRIDE DAY!|
|29.||Onan's Streak||30.||The Guardian|
|31.||Backasswards||32.||Aprils Fool||33.||Pokey Mans||34.||Ultra Hard||35.||Pong|
|The Binding of Isaac: Rebirth|
|Achievements||Attributes||Bosses||Cards and Runes||Challenges||Chapters|