The Left Hand is a trinket.
- The effect includes chests already spawned. Entering a room that previously contained other types of chests while holding The Left Hand will turn them into Red Chests permanently.
- It is advised to drop The Left Hand (by holding either CTRL key for few seconds, holding R2 or RT for 3 seconds on PS4 and Vita and Xbox One, respectively, or holding ZR on the New Nintendo 3DS / Nintendo Switch for a few seconds) before entering The Chest, as it will convert the golden chests there which always contain items.
- The player may prefer red chests for their possible Soul Hearts or red chest items, at the expense of guaranteed items.
- The Left Hand with
Guppy's Tail
Increases chance of finding gold chests and normal chests, but reduces chance of finding pickups. causes all Gold Chests it would usually drop to be Red Chests instead.
PC WJAF PQR1 (Normal room south of spawn).
XboxOne 7AHV RRCH
The Binding of Isaac: Rebirth 
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