The Lost

None 3.5 (*1.00) 1   1 23.75 1.0 0   1 coin Flight D4 Rerolls all of Isaac's items. Spectral tears Holy Mantle Automatically negates first taken damage in every room.   It's complicated Die in a Sacrifice Room while holding Missing Poster The Lost

The Lost is a secret character in The Binding of Isaac: Rebirth.

The Lost starts with no health and cannot increase it by any means. Therefore, it will die from any hit. The Lost starts with flight, Spectral tears, the D4

Rerolls all of Isaac's items.

(if unlocked) and Holy Mantle

Automatically negates first taken damage in every room.

(if unlocked and after donating 879 coins to the Greed Machine). The Lost can take devil deals for free and activate the button in Greed Mode without taking damage.

Notes

• Many of the game's items provide no benefit to The Lost; for example, those that affect health or trigger on taking damage.
• Resurrection items like Dead Cat

  Sets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room. New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again.

  will still work with The Lost, but the life number does not appear on the HUD.
• Devil deals, while free, still count as making a deal with the devil and will prevent angel rooms from opening. Thus, a Credit Card

  Converts all items in the Shop or Devil Room into pickups or items on pedestals, allowing them to be picked up for free. This card's effect lasts for the entire floor, but only affects the room it was used in. Wasted if used outside the shop or the devil room. Allows devil room items to be obtained without affecting the chance of an angel room appearing.

  is still recommended, or getting Chaos

  Chaos causes items to be chosen from random item pools. When picked up, drops between 1-6 random pickups on the floor.

  to acquire angel room items (except broken key pieces).
• Isaac will be replaced by The Lost upon starting a third Victory Lap; however, Victory Laps do not allow the unlocking of achievements.

General Strategies

Main article: The Lost (Strategy)

Unlockable items

• 

  The D100 - Complete the Boss Rush as The Lost.

• 

  -0- Baby - Defeat Mom's Heart on hard mode as The Lost.

• 

  The Mind - Defeat Satan as The Lost.

• 

  Isaac's Heart - Defeat Isaac as The Lost.

• 

  The Soul - Defeat The Lamb as The Lost.

• 

  The Body - Defeat ??? as The Lost.

• 

  Zodiac - Defeat Ultra Greed as The Lost.

• 

  Dad's Lost Coin - Defeat Ultra Greedier as The Lost.

• 

  Sworn Protector - Defeat Hush as The Lost.

• 

  White Baby - Defeat Mega Satan as The Lost.

• 

  Holy Card - Defeat Delirium as The Lost.

• 

  Godhead - Beat Mom's Heart, Isaac, Satan, ???, and The Lamb and complete the Boss Rush on hard mode as The Lost
  Earn all 9 Completion Marks on hard mode as The Lost.

Unlocking The Lost in Afterbirth

The Lost is unlocked by dying in a Sacrifice Room while holding Missing Poster

If Isaac dies in a Sacrifice Room, a puzzle piece will appear on his last will ( and unlocks The Lost). Revives Isaac as The Lost if unlocked. The Missing Poster then disappears.

.

• Looking for Mom's Box

  When used, Mom's Box will drop a random trinket on the ground. While held, increases luck by 1 and doubles the effects of trinkets.

  in shops makes finding the poster easier.

Unlocking The Lost in Rebirth

The Lost is unlocked by dying consecutively with certain characters, with no other deaths. Deaths must be completed in the order shown here, and seeds can be used for the runs except for the last with Azazel:

1. Isaac must die to a Mulliboom in The Basement or The Cellar.
2. Magdalene must die to her own bomb in The Caves or The Catacombs.
3. Judas must die to any Mom attack in The Depths or Necropolis. Being killed by any monster spawned by Mom will spoil the entire attempt at unlocking The Lost.
4. Azazel must die to any Satan attack in Sheol. Being killed by The Fallen in the boss room or a Kamikaze Leech will spoil the entire attempt at unlocking The Lost. Being killed by using The Bible

   Upon activation, Isaac gains flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but will kill Isaac when activated while fighting Satan.

   doesn't count as a Satan kill.

The Lost will be unlocked after dying to Satan's attack.

Notes on unlocking The Lost

• Multiple lives (for example, obtained by Dead Cat

  Sets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room. New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again.

  ) must be depleted before the intended death, as deaths while having extra lives do not count as a game loss.
• Having any mods installed that triggers the mod flag will make The Lost unobtainable. In order to fix this problem, all mods have to be removed.
• The game cannot be won as any character required to unlock it when unlocking it.
• Champion versions of monsters and bosses will count for the death criteria.
• Runs can always be safely reset.
• It should be noted that Mom's Foot's stomp counts as explosive damage, which makes Pyromaniac

  Isaac heals 1 heart instead of taking damage from an explosive source. Adds 5 bombs.

  a problematic choice when trying to complete Step 3.
• Picking the wrong character while unlocking him doesn't mess up the unlocking process.
• Quitting and Restarting the game in the middle of the unlocking process doesn't mess it up.
• Picking up Lazarus' Rags

  Upon dying, resurrect as Revived Lazarus with one heart container and Anemic item.

  , Judas' Shadow

  Adds an extra life; upon death, it respawns Isaac as Black Judas with only two black hearts.

  , or Ankh

  Upon death, the player will respawn as ??? with 3 soul hearts.

  should be avoided. These items will revive the current character as a different one and therefore prevent the current unlock-step from being fulfilled.

File manipulation

By changing a file parameter, an unsuccessful try can be undone:

1. Backup the file Options.ini found in the Documents\My Games\Binding of Isaac Rebirth by making a copy of it in the same folder.
2. Open the original file with Notepad and change the SteamCloud parameter in it to 0. This will disable Steam Cloud gamesaves synchronization.
3. After an unsuccessful try, delete the original file and rename the backup copy with the name of the original file: Options.ini
4. Repeat steps 1 after each successful run until you unlock The Lost.
5. When finished, open the original file and restore the SteamCloud parameter in it to 1. This will enable Steam Cloud gamesaves synchronization again.

Helpful Seeds

Isaac  PC  GPE3 2T1H (Must be on Normal difficulty. 2 Mullibooms south of starting point. Use the sacrifice room above to damage yourself first)  PC   PS4  JTMD EZPF (Must be on Normal difficulty. One mulliboom directly below the starting. Go left first to get weakened)  PC  GH9Y FSA8 (Hard difficulty, series of rooms containing mullibooms going down)  PC  Q2V4 YZET (Hard difficulty, Cellar needs to be unlocked, 2x2 room full of mullibooms (about 6/7) when going up)  Vita  GQHN NMKN (Go left, 4+ Mullibooms)  3DS  6Z2L AZ6J (Go left, 4+ Mullibooms)  3DS  VNSM AHHG (Go up, weaken yourself at the spikes, then go up and die from the Mulliboom) Maggy  PC  ALFA 0NTS (Recommended Normal difficulty. Pyro in the first Treasure Room, adjacent to spawn)  PS4  FDRG 0CTE (Pyro in the first Treasure Room, adjacent to spawn)  Vita  DXVW MQCF (Pyro in the first Treasure Room)  3DS  YGDC T8SL (10 bombs in the first Treasure Room) Judas  PC  YR8E YXDV (Must be on Normal difficulty. Polyphemus in the first Treasure Room. Do not take devil deals, as Trinity Shield and Sacred Heart will be available in Angel Rooms. Keep the Book of Belial to ensure they show up. Also, from the pills from Mom's Coin Purse (1st boss, Duke of Flies), take the orange (Health Up) then the white one (Full Health), ignore the blue ones (Speed Down)).  PC  N0G3 VLD4 (Both modes) - Dr. Fetus on floor 1, and Ipecac on floor 2.  PS4  DMTM NRD9 (Do not making a Devil Room deal in Basement II will spawn an Angel Room with Holy Grail in Caves I. Collecting everything grant huge tears.  3DS  180Y 7RDC (Lots of health early (Rosary in first Treasure room), good pickups (Mulligan is in second Treasure room, Dr Fetus and Mr Mega in the third and fourth). Skip the first Devil deal, as the Angel deals are Sacred Heart, Mitre, and Scapular. Remember to trigger scapular before entering the Mom fight if you take it, as the immediate foot stomp may leave you with the bonus soul heart.) The Lost  PC  HNA6 WEK7 (Dead Cat and Holy Mantle on first floor, helpful for practice runs)

Gallery

• 

  The Lost on the character select screen.

• 

  The Lost on the boss vs. screen.

• 

  The Lost on the next floor screen.

Trivia

• When The Lost's unlock requirements were discovered through the use of data mining, Edmund McMillen and Tyrone Rodriguez both expressed their disappointment, considering it impatient and "like swallowing a hundred dollar steak in one bite".
• Right before the start of a run, there are images that appear to hint to unlocking The Lost, including the Missing Poster

  If Isaac dies in a Sacrifice Room, a puzzle piece will appear on his last will ( and unlocks The Lost). Revives Isaac as The Lost if unlocked. The Missing Poster then disappears.

  and The Lost itself.
• Dying in a Sacrifice Room while holding the Missing Poster

  If Isaac dies in a Sacrifice Room, a puzzle piece will appear on his last will ( and unlocks The Lost). Revives Isaac as The Lost if unlocked. The Missing Poster then disappears.

  would yield a puzzle piece on Isaac's last will. These puzzle pieces, when put together, created the last wills of characters dying in the method used to unlock The Lost.
• Prior to version 1.02, The Lost would die if a run was exited then continued.
• When The Lost picks up an item, tarot card, or pill, you can see its arms which do not connect to its body.
• One common (but unconfirmed) theory suggests that the single coin which The Lost starts with may be a reference to Charon's obol, a coin which was placed in the mouth of a dead person prior to burial in ancient Greek civilization. Placing the obol in the mouth ensured that the dead person would hold onto the obol after death. This obol was to be used by their ghost to pay Charon, the ferryman who would take souls across the river Styx into the underworld in exchange for a coin. Souls who did not have an obol could not pay Charon and would not be able to cross the river.
• Internally, The Lost has half a soul heart, which is hidden behind a permanent Curse of the Unknown-like effect. This causes extra lives to be hidden from The Lost's HUD. The singular soul heart is why The Lost is able to "pick up" soul hearts, black hearts, and eternal hearts. There are no ways to increase this health, though, as The Lost's health is constantly reset back to half a soul heart.
  • Devil deals appear as requiring three soul hearts each as The Lost technically only has half of an invisible soul heart. This is cosmetic only, as devil deals are still free.
• A loading screen (when Isaac dreams) depicts the "Voice of God" telling Isaac's Mom to kill her son as The Lost speaking to her from the attic.

References

Characters
Rebirth	Afterbirth	Afterbirth †