| 6 rooms|
| (page 1, column 15, line 2)
(page 1, column 5, line 4)
| Use XIII - Death 4 times |
The Necronomicon is an unlockable activated item.
- Inflicts 40 damage to every enemy in the room.
- Many collectibles will produce effects similar to the Necronomicon, such as depleting a black heart or blocking projectiles with Dry Baby.
- The Necronomicon deals a considerable amount of damage to bosses that have multiple damageable parts, e.g. Larry Jr. and The Hollow.
- This item also deals high enough damage to instantly kill most non-boss enemies.
- This item counts toward the Bookworm transformation, allowing Isaac to shoot double tears occasionally.
Picture of The Necronomicon when activated
3DS The Icon of The Necronomicon as seen on the lower 3DS screen
- A Missing Page and Missing Page 2 are both references to missing pages of the Necronomicon appearing in Evil Dead.
- Which, in turn, is a reference to the Necronomicon, a fictional grimoire appearing in the works of horror writer H.P. Lovecraft.
- The Book is bound in human skin, which explains the face on its cover.
- The face on the cover is a reference to The Evil Dead franchise, which has the same face on its Necronomicon.