Time penalty

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Time penalty is how many points you lose in a run for spending time clearing floors, and it varies according to the events you've cleared throughout the run.

The formula(s) behind Time penalty are as follows:

TimePenalty = Floor(Ceil(((Rush_Bonus
                         + Mega_Satan_Bonus
                         + Lamb_Bonus
                         + XXX_Bonus
                         + Stage_Bonus) * 0.80) * (1.0 - SecondsPenalty)))

Where SecondsPenalty is:

 SecondsPenalty = Exp((Elapsed_Seconds * -0.22) / BaseStagePenalty)

And, in turn BaseStagePenalty is the sum of several fixed amounts of points per each stage and event, called "Expected Stage Times":

Stage reached / event Value
1 (Basement 1) 60
2 (Basement 2) 60
3 (Caves 1) 120
4 (Caves 2) 180
5 (Depths 1) 180
6 (Depths 2) 300
Boss rush cleared 240
7 (Womb 1) 300
8 (Womb 2) 360
9 (Blue Womb) 360
10 (Sheol / Cathedral)
11a (Dark Room / Chest) 420*
11b (Mega Satan) 420
12 (The Void)

* from killing Satan / Isaac in stage 10

Using a Forget Me Now or a 5-pips Dice room will not alter those values.