Toxic Shock

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Item icon
Item altar
Table dividing line 1.png
Character appearance
Table dividing line 2.png
Treasure Room Treasure Room
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(page 3, column 5, row 6)
Added in  Afterbirth

Toxic Shock is a passive item added in the Binding of Isaac: Afterbirth expansion.

Effects[edit | edit source]

  • Upon entering a room, all enemies are poisoned, dealing double Isaac's tear damage and also creating a green fog for the first few seconds of the room.
  • Killing enemies leaves a small, short lasting pool of green creep on the ground.
    • The creep deals 1 damage per tick or 30 damage per second.

Notes[edit | edit source]

  • High tear damage will cause this item to become very powerful for rooms with a lot of enemies, since they can die instantly and render the room harmless.
  • Enemies which spawn after the first few seconds of each room are not affected by this item, e.g. Flies spawned from a Mulligan dying.
  • The poison effect only activates upon entering a room and not at the start of a wave. In Boss Rush and most of Greed Mode, the item will not poison enemies.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Added in Afterbirth †Contagion ContagionContagion Icon.pngThe first enemy killed in a room explodes and poisons nearby enemies. Poisoned enemies will also explode upon death. is a recolor of its sprite.
  • Toxic Shock is a rare, but extremely serious and deadly condition caused by Staphylococcus Aureus bacteria releasing toxins in the bloodstream.

Seeds[edit | edit source]

 PC  MS6L 43MM (First floor treasure room) (Hard Mode Only)

 PC  0DMW R92S (First floor treasure room)

 PC  E3ER VEGE (First floor treasure room) (Both modes)

 Switch  Added in Afterbirth † 7YV6 DDJ1 (Treasure room adjacent to spawn)