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Guppy Beelzebub Added in  Afterbirth Super Bum Added in  Afterbirth Yes Mother? Added in  Afterbirth Bob Added in  Afterbirth Fun Guy Added in  Afterbirth Leviathan Added in  Afterbirth Conjoined
Added in  Afterbirth Spun Added in  Afterbirth Seraphim Added in  Afterbirth Oh Crap Added in Afterbirth † Bookworm Added in Afterbirth † Spider Baby Added in Afterbirth † Adult Added in Afterbirth † Stompy

Transformations alter Isaac's appearance and grant him special abilities.

A transformation occurs when obtaining at least three different items from a particular set of items.
These collectibles always share a particular theme that corresponds with the transformation.

Transformation sets[edit | edit source]

Name Appearance Description Items
Beelzebub Beelzebub
Guppy Guppy
Added in  Afterbirth Bob Bob
Added in  Afterbirth Conjoined Conjoined
  • When attacking, the tumor faces shoot tears diagonally outwards, similar to the effect of The Wiz The WizThe Wiz Icon.pngTears simultaneously fire out of both eyes diagonally, similar to the effect of the R U A Wizard? pill. Isaac's tears also travel above all obstacles..
  • -0.3 damage.
  • Slightly decreases tears.
Added in  Afterbirth Fun Guy Fun Guy
Added in  Afterbirth Leviathan Leviathan

Flight.+2 black hearts.

Added in  Afterbirth Oh Crap Oh Crap
  • Whenever a pile of poop is destroyed, health is replenished by half a heart.
Added in  Afterbirth Seraphim Seraphim
Added in  Afterbirth Spun Spun
Added in  Afterbirth Super Bum Super Bum
  • Replaces Bum Friend Bum FriendBum Friend Icon.pngA portable beggar who follows Isaac, picks up coins for himself, and occasionally drops a pickup after collecting a coin. Does not spawn collectibles., Dark Bum Dark BumDark Bum Icon.pngSpawns a familiar that follows Isaac around and collects red hearts. For every one-and-a-half red hearts collected, Dark Bum will generate one soul heart, one hostile Spider or one friendly blue spider., and Key Bum Key BumKey Bum Icon.pngSpawns a portable key master that follows Isaac and collects keys, giving random chests in return. for Super Bum.
  • Collects any of the other beggars' pickups, and offers twice the rewards.
Added in  Afterbirth Yes Mother? Yes Mother?
  • Isaac gains a stationary knife that trails directly behind him. It synergizes like Mom's Knife Mom's KnifeMom's Knife Rebirth Icon.pngIsaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power. would.
Added in Afterbirth † Adult Adult
  • Grants a heart container.
Added in Afterbirth † Bookworm Bookworm
  • Roughly 50% of the time, Isaac shoots an extra tear, like 20/20 20/2020 20 Rebirth Icon.pngGrants double shot..
Added in Afterbirth † Spider Baby Spider Baby
  • Spawns a spider familiar that applies random status effects to enemies it comes in contact with.
Added in Afterbirth † Stompy None
  • Taking damage has a chance to spawn rock waves.

Requirements[edit | edit source]

  • Items only need to have been acquired once in order to count. Keeping them is not required.
    • Duplicate items (like those acquired from Added in  AfterbirthDiplopia DiplopiaDiplopia Icon.pngOne time useDuplicates all pickups and item pedestals in the room.) do not count toward transformations when picked up. Only the first instance of an item Isaac owns will count.
    • Activated collectibles (e.g. Guppy's Head Guppy's HeadGuppy's Head Icon.png1 roomsSpawns 2-4 blue flies to damage enemies.) can be picked up once and then swapped away with another without any loss to transformation progress.
    • Rerolling items with a dice room, the D4 D4D4 Icon.png6 roomsRerolls all of Isaac's items., or the D100 D100D100 Icon.png6 roomsUpon use, rerolls all passive items on Isaac like the D4, every pedestal item in the room like The D6, and every pickup like the D20. will not remove progress towards the transformation.
    • Added in  Afterbirth Familiars gained fromCambion Conception Cambion ConceptionCambion Conception Afterbirth Icon.pngAfter taking damage a certain amount of times, a permanent demonic familiar spawns. orImmaculate Conception Immaculate ConceptionImmaculate Conception Icon.pngUpon picking up a certain amount of health, spawn a permanent angelic familiar. do not count towards transformation progress.
  • Trinkets do not count toward progress for any transformation.
  • Pills only count toward Adult and Stompy, they do not count toward progress for any other transformation.

Notes[edit | edit source]

  • Transformations can be combined with each other, keeping the effects of any and all transformations with no effects overriding others.
  • Transforming into Beelzebub for the first time will unlock the Lord of the Flies achievement and Added in Afterbirth †Angry Fly Angry FlyAngry Fly Icon.pngSpawns a fly familiar that orbits around a random enemy and deals 5 damage per tick to enemies it comes in contact with..
  • Since none of the Afterbirth transformations unlock an achievement or item, attaining them is not required for 100% completion of the game in terms of achievements. However, this is only true if you unlockedMom's Contacts Mom's ContactsMom's Contacts Rebirth Icon.pngAdds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. Range up. on Rebirth, as the Added in  Afterbirth Yes Mother? transformation will happen once you collect three Mom items on Afterbirth and Afterbirth † .
  • Many of the Afterbirth transformations override the charge animations of items such as Monstro's Lung Monstro's LungMonstro's Lung Icon.pngIncreases damage and grants a charged shot that fires multiple tears in the same fashion as Monstro. and Brimstone BrimstoneBrimstone Rebirth Icon.pngTears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period., potentially making them more difficult to use.
    • Added in Afterbirth † There is now an option to show a charge bar that floats above Isaac.

Trivia[edit | edit source]

  • There are two transformations in the base game, nine more in the Afterbirth DLC, and four more in the Afterbirth † DLC.
  • In the original The Binding of Isaac flash game, the transformation into Guppy was the only one available, making it chronologically the first.
    • The Eternal Edition of the original The Binding of Isaac game added another transformation that turned Isaac into an angel after gaining 7 heart containers from eternal hearts.
  • Rebirth introduced Beelzebub as the chronologically second transformation.
  • The original name for the Beelzebub transformation was Lord of the Flies.

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