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Guppy Beelzebub Added in Afterbirth Super Bum Added in Afterbirth Yes Mother? Added in Afterbirth Bob Added in Afterbirth Fun Guy Added in Afterbirth Leviathan Added in Afterbirth Conjoined
Added in Afterbirth Spun Added in Afterbirth Seraphim Added in Afterbirth Oh Crap Added in Afterbirth † Bookworm Added in Afterbirth † Spider Baby Added in Afterbirth † Adult Added in Afterbirth † Stompy

Transformations alter Isaac's appearance and grant him special abilities.

A transformation occurs when obtaining at least three different items from a particular set of items.
These collectibles always share a particular theme that corresponds with the transformation.

Transformation sets[edit | edit source]

Name Appearance Description Items
Beelzebub Beelzebub

Grants flight and converts small enemy flies into blue flies.

Guppy Guppy

Grants flight and spawns a blue fly each time a tear hits an enemy.

Added in Afterbirth Bob Bob

Isaac gains a green trail of poisonous creep.

Added in Afterbirth Conjoined Conjoined

When attacking, the tumor faces shoot tears diagonally outwards, similar to the effect ofThe Wiz The WizCollectible The Wiz icon.pngTears simultaneously fire out of both eyes diagonally, similar to the effect of the R U A Wizard? pill. Isaac's tears also travel above all obstacles.. Also gives -0.3 damage and slightly decreases tears.

Added in Afterbirth Fun Guy Fun Guy

+1 heart container.

Added in Afterbirth Leviathan Leviathan

Grants flight and gives +2 black hearts.

Added in Afterbirth Oh Crap Oh Crap

Whenever a pile of poop is destroyed, health is replenished by half a heart.

Added in Afterbirth Seraphim Seraphim

Grants flight and gives +3 soul hearts.

Added in Afterbirth Spun Spun

Gives +2 damage and +0.15 speed, and spawns a random pill upon transformation.

Added in Afterbirth Super Bum Super Bum

Replaces Bum Friend Bum FriendCollectible Bum Friend Rebirth icon.pngA portable beggar who follows Isaac, picks up coins for himself, and occasionally drops a pickup after collecting a coin. Does not spawn collectibles., Dark Bum Dark BumCollectible Dark Bum Rebirth icon.pngSpawns a familiar that follows Isaac around and collects red hearts. For every one-and-a-half red hearts collected, Dark Bum will generate one soul heart, one hostile Spider or one friendly blue spider., andKey Bum Key BumCollectible Key Bum Afterbirth icon.pngSpawns a portable key master that follows Isaac and collects keys, giving random chests in return. for Super Bum. This bum collects any of the other beggars' pickups, and offers twice the rewards.

Added in Afterbirth Yes Mother? Yes Mother?

Isaac gains a stationary knife that trails directly behind him. It synergizes like Mom's Knife Mom's KnifeCollectible Mom's Knife Rebirth icon.pngIsaac's tears are replaced by a knife that pierces enemies, can travel through obstacles and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power. would.

Added in Afterbirth † Adult Adult

Grants a heart container.

Added in Afterbirth † Bookworm Bookworm

Roughly 50% of the time, Isaac shoots an extra tear, like 20/20 20/2020 20 Rebirth Icon.pngGrants double shot..

Added in Afterbirth † Spider Baby Spider Baby

Spawns a spider familiar that applies random status effects to enemies it comes in contact with.

Added in Afterbirth † Stompy None

Taking damage has a chance to spawn rock waves.

Requirements[edit | edit source]

  • Items only need to have been acquired once in order to count. Keeping them is not required.
    • Duplicate items (like those acquired from Added in AfterbirthDiplopia DiplopiaCollectible Diplopia icon.pngOne time useDuplicates all pickups and item pedestals in the room.) do not count toward transformations when picked up. Only the first instance of an item Isaac owns will count.
    • Activated collectibles (e.g. Guppy's Head Guppy's HeadCollectible Guppy's Head icon.png1 roomsSpawns 2-4 blue flies to damage enemies.) can be picked up once and then swapped away with another without any loss to transformation progress.
    • Rerolling items with a dice room, the D4 D4Collectible D4 icon.png6 roomsRerolls all of Isaac's items., or the D100 D100Collectible D100 icon.png6 roomsUpon use, rerolls all passive items on Isaac like the D4, every pedestal item in the room like The D6, and every pickup like the D20. will not remove progress towards the transformation.
    • Added in Afterbirth Familiars gained fromCambion Conception Cambion ConceptionCollectible Cambion Conception Afterbirth icon.pngAfter taking damage a certain amount of times, a permanent demonic familiar spawns. orImmaculate Conception Immaculate ConceptionCollectible Immaculate Conception icon.pngUpon picking up a certain amount of health, spawn a permanent angelic familiar. do not count towards transformation progress.
  • Trinkets do not count toward progress for any transformation.
  • Pills only count toward Adult and Stompy, they do not count toward progress for any other transformation.

Notes[edit | edit source]

  • Transformations can be combined, keeping the effects of all transformations with no effects overriding others.
  • Transforming into Beelzebub for the first time will unlock the Lord of the Flies achievement and Added in Afterbirth †Angry Fly Angry FlyCollectible Angry Fly icon.pngSpawns a fly familiar that orbits around a random enemy and deals 5 damage per tick to enemies it comes in contact with..
  • Since none of the Afterbirth transformations unlock an achievement or item, attaining them is not required for 100% completion of the game in terms of achievements. However, this is only true if you unlockedMom's Contacts Mom's ContactsCollectible Mom's Contacts Rebirth icon.pngAdds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. Range up. on Rebirth, as the Added in Afterbirth Yes Mother? transformation will happen once you collect three Mom items on Afterbirth and Afterbirth †.
  • Many of the Afterbirth transformations override the charge animations of items such as Monstro's Lung Monstro's LungCollectible Monstro's Lung icon.pngIncreases damage and grants a charged shot that fires multiple tears in the same fashion as Monstro. and Brimstone BrimstoneCollectible Brimstone Rebirth icon.pngTears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period., potentially making them more difficult to use.
    • Added in Afterbirth † There is now an option to show a charge bar that floats above Isaac.

Gallery[edit | edit source]

Trivia[edit | edit source]

  • There are two transformations in the base game, nine more in the Afterbirth DLC, and four more in the Afterbirth † DLC.
  • In the original The Binding of Isaac flash game, the transformation into Guppy was the only one available, making it chronologically the first.
    • The Eternal Edition of the original The Binding of Isaac game added another transformation that turned Isaac into an angel after gaining 7 heart containers from eternal hearts.
  • Rebirth introduced Beelzebub as the chronologically second transformation.
  • The original name for the Beelzebub transformation was Lord of the Flies.

The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets