Name
|
ID
|
Icon
|
Quote
|
Description
|
20/20
|
245
|
|
Double shot
|
Isaac fires two tears at once, one from each eye.
|
3 Dollar Bill
|
191
|
|
Rainbow tears
|
Gives Isaac a random tear effect every room.
Gives Isaac a random tear effect every few seconds.
|
8 Inch Nails
|
359
|
|
Stick it to 'em!
|
+1.5 Damage Up. Replaces Isaac's tears with nails, which have increased knockback.
|
???'s Only Friend
|
320
|
|
Controlled friend
|
Summons a big attack fly that can be controlled with the shooting direction-keys.
|
A Lump of Coal
|
132
|
|
My Xmas Present
|
The more distance tears travel, the more damage they will do.
|
Abel
|
188
|
|
Mirrored buddy
|
A familiar that mirrors the player's movements and shoots in the opposite direction.
|
Anemic
|
214
|
|
Toxic blood
|
+5 range. After Isaac is damaged, a trail of red creep will be left behind Isaac until he leaves the current room.
|
Ankh
|
161
|
|
Eternal life?
|
Upon death, the player will respawn as ??? with 3 Soul Hearts.
|
Anti-Gravity
|
222
|
|
Antigravity tears + tears up
|
-2 Tear Delay. Tears float in position until firing ceases, after which they will fly off in the direction they were shot in.
|
Aquarius
|
308
|
|
Trail of tears
|
A trail of blue creep is left behind Isaac, which damages enemies.
|
Aries
|
300
|
|
Ramming speed
|
+0.25 Speed. Running into enemies while at a high speed will deal 18 points of damage. Does not prevent contact damage.
|
Ball of Tar
|
231
|
|
Sticky feet...
|
Adds a chance to shoot slowing tears and the character leaves a trail of slowing creep behind as he moves, impeding enemies' speed.
|
Best Bud
|
274
|
|
Sworn protector
|
When hit, summons a white attack fly similar to Distant Admiration for the current room.
|
Betrayal
|
391
|
|
Turn your enemy
|
Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac.
|
Big Fan
|
279
|
|
Fat protector
|
Spawns a large orbital familiar that blocks enemy projectiles and deals slight contact damage to enemies.
|
Black Lotus
|
226
|
|
HP up x3!
|
Grants the player one Red Heart container, one Soul Heart, and one Black Heart.
|
Blood Clot
|
254
|
|
DMG + range up
|
Increases damage by 1 and range by 5 for tears fired from the left eye.
|
Blood of the Martyr
|
7
|
|
DMG up
|
Increases Damage by 1, and turns Isaac's tears into blood tears.
|
Bloody Lust
|
157
|
|
RAGE!
|
Increases damage as Isaac receives damage. Damage increase stays for the whole floor.
|
Bob's Brain
|
273
|
|
Explosive thoughts
|
Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds.
|
Bob's Curse
|
140
|
|
+5 poison bombs
|
Gives 5 bombs and grants all bombs poison effect.
|
Bobby-Bomb
|
125
|
|
Homing bombs!
|
Gives Isaac 5 Bombs and causes all dropped bombs to home towards the closest enemy.
|
The Body
|
334
|
|
I feel all
|
Adds 3 Heart Containers.
|
Bomb Bag
|
131
|
|
Gives bombs
|
Isaac is followed by a small bag that drops a Bomb, a Double Bomb, a Troll Bomb, or a Golden Bomb every 3 rooms.
|
Bomber Boy
|
353
|
|
Explosive blast!
|
+5 bombs. Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide). This also affects player-spawned Troll Bombs.
|
Brother Bobby
|
8
|
|
Friends 'till the end
|
Follows Isaac around shooting normal tears.
|
Bursting Sack
|
377
|
|
Spider love
|
Spider enemies no longer target or deal contact damage to Isaac.
|
Butt Bombs
|
209
|
|
Toxic blast +5 bombs
|
+5 bombs. Bombs now cloud up the screen, briefly damaging and confusing all enemies.
|
Cain's Other Eye
|
319
|
|
Near-sighted friend
|
Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to The Peeper and shoots normal tears in the same direction as Isaac.
|
Cancer
|
301
|
|
HP up + you feel protected
|
Adds 3 Soul Hearts. Grants The Wafer effect for the current room upon taking damage.
|
Capricorn
|
307
|
|
All stats up
|
Increases health, damage, speed, and range, lowers tear delay, and gives one coin, bomb, and key.
|
Celtic Cross
|
162
|
|
You feel blessed
|
Grants a chance to trigger the Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
|
Charm of the Vampire
|
62
|
|
Kills heal
|
Heals the character for half of a Red Heart for every 13 monsters killed.
|
Chemical Peel
|
154
|
|
DMG up
|
Tears fired from left eye do increased damage.
|
Chocolate Milk
|
69
|
|
Charge shots
|
Grants charged tears that deal greater damage when fully charged.
|
The Common Cold
|
103
|
|
Poison Damage
|
Adds a chance to shoot poison tears, dealing damage over time when inflicted.
|
Continuum
|
369
|
|
Transcendent tears
|
+2.25 range up. +1.5 tear height. Isaac's tears travel through walls and appear out of the opposite wall. Isaac's tears also travel over rocks and objects.
|
Cricket's Body
|
224
|
|
Tears up + splash damage
|
Grants -1 tear delay and reduces range. When tears hit an object or deplete their range, they spawn 4 smaller tears, whose range and damage scale with Isaac's.
|
Cricket's Head
|
4
|
|
DMG up
|
Increases damage by 0.5, and multiplies it by 1.5x.
|
Cube of Meat
|
73
|
|
Gotta meat 'em all!
|
Orbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, it makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages.
|
Cupid's Arrow
|
48
|
|
Piercing shots
|
Grants Isaac piercing tears that travel through enemies (but not obstacles) instead of breaking on impact with them.
|
Curse of the Tower
|
371
|
|
You feel cursed...
|
Causes Isaac to spawn 6 Troll Bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic.
|
Cursed Eye
|
316
|
|
Cursed charge shot
|
Grants charged tears that can be fired in a tight burst of four. Getting hit while charging will teleport Isaac into another room.
|
Daddy Longlegs
|
170
|
|
Daddy's love
|
Daddy Long Legs' shadow follows Isaac and stomps on enemies.
|
Dead Bird
|
117
|
|
Protective buddy
|
Spawns a flying familiar for the current room that chases enemies whenever Isaac takes damage.
|
Dead Eye
|
373
|
|
Accuracy brings power!
|
Isaac's damage increases each time an enemy is hit. Damage is reset upon missing a shot.
|
Dead Onion
|
336
|
|
Toxic aura tears
|
Grants piercing and spectral tears. Increases tear size (without increasing damage) while greatly reducing range and shot speed.
|
Death's Touch
|
237
|
|
Penetrative shot + damage up
|
+1.5 damage, -0.3 tears. Tears are replaced with large piercing scythes.
|
Deep Pockets
|
416
|
|
More stuff to carry!
|
Allows Isaac to carry two cards or pills (or a combination of both) at the same time.
|
Distant Admiration
|
57
|
|
Attack fly
|
A red attack fly circles further out than the Halo of Flies / Pretty Flies, but closer than Forever Alone. Deals more damage than Forever Alone.
|
Dr. Fetus
|
52
|
|
???
|
Tears are replaced by bombs that benefit from bomb-enhancing effects and slide for a fixed time after being fired.
|
Dry Baby
|
265
|
|
Immortal Friend
|
Spawns a familiar that follows Isaac around and blocks enemy projectiles. Upon blocking a shot, it has a chance of triggering The Necronomicon effect.
|
E Coli
|
236
|
|
Turdy touch
|
Gives "Turdy Touch" effect. Enemies that touch Isaac are changed into poop.
|
Epic Fetus
|
168
|
|
On-demand air strike
|
Isaac's tears are replaced with guided missiles, like those used by the Doctor's Remote.
|
Epiphora
|
368
|
|
Intensifying tears
|
Shooting in one direction increases Isaac's rate of fire until the cap is reached. As soon as Isaac changes direction or stops shooting, rate of fire is reset to its normal amount.
|
Eve's Mascara
|
310
|
|
Shot speed down + DMG up
|
Doubles damage, halves tears stat, and greatly reduces shot speed.
|
Evil Eye
|
410
|
|
Eye shot!
|
While firing tears, Isaac has a chance to fire an eye across the screen with a very slow shot speed, which will fire tears of its own in the same direction as Isaac. The eye will be destroyed if it comes into contact with an enemy or obstacle.
|
Explosivo
|
401
|
|
Sticky bomb shot!
|
Isaac's tears have a chance to stick to enemies and explode.
|
Fire Mind
|
257
|
|
Flaming tears
|
Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion.
|
Forever Alone
|
128
|
|
Attack fly
|
Spawns a blue attack fly that orbits a long distance from Isaac.
|
Friend Zone
|
364
|
|
Friendly fly
|
A white orbiting fly which deals 3 contact damage per tick to enemies. This familiar orbits Isaac at a middle length distance somewhere between Distant Admiration and Forever Alone.
|
Gemini
|
318
|
|
Conjoined friend
|
Suture becomes attached to Isaac, and does touch damage to enemies within its attacking range.
|
Ghost Baby
|
163
|
|
Spectral buddy
|
Spawns a familiar that follows Isaac around and fires spectral tears.
|
Glitter Bombs
|
432
|
|
Prize bombs!
|
Gives Isaac 5 bombs, and makes Isaac's bombs have a chance to drop random pickups or charm enemies when they explode.
|
Gnawed Leaf
|
210
|
|
Unbreakable
|
After standing still and not shooting for a short time, Isaac turns invincible until he moves or shoots.
|
God's Flesh
|
398
|
|
Shrink shot
|
Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size and also run away from Isaac. Shrunk enemies can be crushed and killed by walking over them.
|
Godhead
|
331
|
|
God tears
|
Increases damage and range while reducing tears and shot speed. Grants homing tears and tears gain a damaging halo.
|
Guillotine
|
206
|
|
An out-of-body experience
|
Isaac's head is removed from his body and floats around him. Increases Damage by 1 and grants -1 Tear Delay.
|
The Halo
|
101
|
|
All stats up
|
Grants one Heart Container, +0.3 Damage, +0.2 Tears, +0.25 Range, +0.3 Speed, and +0.5 Tear Height.
|
Halo of Flies
|
10
|
|
Projectile protection
|
Spawns two Pretty Flies that block enemy shots and deal contact damage to flies.
|
Harlequin Baby
|
167
|
|
Double shot buddy
|
Spawns a familiar that follows Isaac around and fires two tears at once in a V-pattern.
|
Headless Baby
|
269
|
|
Bloody Friend
|
Familiar that follows Isaac, leaving blood creep on the ground.
|
Holy Light
|
374
|
|
Holy shot!
|
Isaac has a random chance to fire a Holy tear, which, when it hits an enemy, will spawn a Crack the Sky-style light beam on the same enemy, dealing damage.
|
Host Hat
|
375
|
|
Nice hat!
|
A host familiar that sits on Isaac's head and has a random chance to block enemy shots and retaliate with 3 tears. Grants immunity to explosions.
|
Hot Bombs
|
256
|
|
Burning blast +5 bombs
|
Grants 5 bombs. Isaac's bombs leave behind fire that damages enemies upon contact.
|
Infamy
|
242
|
|
Damage Reduction
|
Chance to block projectiles coming from any direction.
|
Infestation
|
148
|
|
They grow inside
|
1-3 Blue Flies randomly spawn every time Isaac gets hit.
|
Infestation 2
|
234
|
|
Infestation shot
|
Spawns allied Blue Spiders from killed enemies.
|
The Inner Eye
|
2
|
|
Triple shot
|
Grants triple shot but decreases tears.
|
Ipecac
|
149
|
|
Explosive shots
|
Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth.
|
Iron Bar
|
201
|
|
Concussive tears
|
Increases damage by 0.3 and adds a chance to shoot concussive tears, causing enemies to walk around randomly.
|
Judas' Shadow
|
311
|
|
Sweet revenge
|
Adds an extra life; upon death, it respawns Isaac as Black Judas with only two black hearts.
|
Juicy Sack
|
266
|
|
Sticky babies
|
A familiar that follows behind Isaac. It drips a trail of creep, which slows enemies, and spawns 1-2 blue spiders after each room.
|
Kidney Stone
|
440
|
|
Matt's kidney stone
|
Randomly while firing tears, Isaac will stop firing and turn red, where he will charge and release a lot of 'tears' in one go. The burst of tears also includes a kidney stone, which deals a lot of damage.
|
Lazarus' Rags
|
332
|
|
Eternal Life?
|
Upon dying, resurrect as Revived Lazarus with one heart container and Anemic item.
|
Leo
|
302
|
|
Stompy
|
Isaac can destroy rocks by walking into them.
|
Lil Chest
|
362
|
|
What's in the box?
|
Spawns a chest familiar that follows Isaac and drops a random pickup every few rooms.
|
Lil Gurdy
|
384
|
|
A gurd of your own!
|
Gives Isaac a Gurdy familiar that will charge around the room dealing contact damage to enemies. Lil Gurdy is charged by holding down a fire button and letting go. The longer the button is held, the faster Lil Gurdy will fling itself across the screen. Lil Gurdy can pass over objects and obstacles in the room.
|
Lil Haunt
|
277
|
|
Fear him
|
A familiar that damages enemies by chasing them as well as inducing the fear effect.
|
Little C.H.A.D.
|
96
|
|
Gives kisses
|
A familiar who will drop a half red heart every 3 rooms.
|
Little Chubby
|
88
|
|
Attack Buddy
|
A charger familiar that charges forward and deals touch damage to any enemies in its path.
|
Little Gish
|
99
|
|
Sticky friend
|
Spawns a familiar that follows Isaac around and fires slowing tears, impeding enemies' speed.
|
Little Steven
|
100
|
|
Psychic friend
|
Spawns a familiar that follows Isaac around and fires homing tears.
|
Loki's Horns
|
87
|
|
Cross Tears
|
Gives a random chance for projectiles to fire in all 4 cardinal directions.
|
Lost Contact
|
213
|
|
Shielded tears
|
Every tear has a small shield which will allow it to block one enemy projectile.
|
Lost Fly
|
365
|
|
Lost protector
|
A familiar fly that moves in a straight line and attaches itself to the first obstacle or wall it comes into contact within each room. If any enemies walk into its path, it will do 7 contact damage per tick. If the obstacle it is attached to is destroyed then it will continue rolling in the direction it was previously traveling until it meets another wall or obstacle.
|
The Ludovico Technique
|
329
|
|
Controlled Tears
|
Instead of firing tears, Isaac controls one floating tear that hover over obstacles. This tear deals constant damage when held in place over an enemy.
|
Lusty Blood
|
411
|
|
Their blood brings rage!
|
Isaac's damage increases for the current room each time he kills an enemy.
|
Maggy's Bow
|
312
|
|
HP up + you feel healthy
|
Gives one heart container and doubles the healing provided by red hearts.
|
Magic Mushroom
|
12
|
|
All Stats Up!
|
Increases most stats, enlarges Isaac, grants a heart container and restores all health.
|
Marked
|
394
|
|
Directed tears
|
Isaac will now fire tears automatically directed at a red target on the ground which is controlled by the player. This allows for a full 360-degree tear firing radius. It can be overridden by other tear modifiers such as Mom's Knife or Brimstone.
|
Milk!
|
436
|
|
Don't cry over it...
|
A glass of milk follows Isaac and spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the rest of the room.
|
The Mind
|
333
|
|
I know all
|
Grants the combined effects of the Blue Map, Treasure Map, and The Compass, revealing the floor layout and all special rooms, including Secret Rooms and Super Secret Rooms.
|
Missing No.
|
258
|
|
Syntax error
|
Randomizes all passive items and stats upon pickup and at the start of each succeeding floor.
|
Mom's Contacts
|
110
|
|
Freeze effect
|
Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. Range up.
|
Mom's Eyeshadow
|
200
|
|
Charm tears
|
Tears have a chance to charm enemies.
|
Mom's Eye
|
55
|
|
Eye in the back of your head
|
Allows Isaac to fire tears from the back of his head.
|
Mom's Knife
|
114
|
|
Stab stab stab
|
Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.
|
Mom's Perfume
|
228
|
|
Fear shot
|
Adds a chance to shoot fear tears and decreases tear delay by 1.
|
Monstro's Lung
|
229
|
|
Charged attack
|
Increases damage and grants a charged shot that fires multiple tears in the same fashion as Monstro.
|
Mr. Mega
|
106
|
|
Blast damage
|
Gives Isaac 5 bombs, and makes all dropped bombs larger, which have an increased blast radius and increased damage.
|
The Mulligan
|
151
|
|
They grow inside
|
Tears have a 1/6 chance of spawning allied blue flies when they hit an enemy.
|
Multidimensional Baby
|
431
|
|
ydduB Buddy
|
Spawns a familiar that will follow Isaac's movements on a 2.5-second delay. Tears that pass through the baby will be doubled and increase in speed.
|
Mutant Spider
|
153
|
|
Quad shot
|
Grants quadruple shot but decreases tears.
|
My Reflection
|
5
|
|
Boomerang tears
|
Gives Isaac's tears a boomerang effect, and increases range and shot speed.
|
Mysterious Liquid
|
317
|
|
Toxic Splash Damage
|
Tears leave a small, short lasting pool of creep on impact or when their range is depleted.
|
Mystery Sack
|
271
|
|
?
|
Spawns a familiar that drops a heart, coin, bomb, or key every 5-6 rooms.
|
Night Light
|
425
|
|
Scared of the dark?
|
A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots.
|
No. 2
|
378
|
|
Uh oh...
|
Continuously firing tears for several seconds causes Isaac to drop a Butt Bomb. Butt Bombs explode for 60 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time.
|
Number One
|
6
|
|
Tears up
|
+1.5 tears, -17.62 range
|
Obsessed Fan
|
426
|
|
Follows my every move...
|
A purple fly familiar that follows Isaac's movements on a 3 second delay and deals contact damage to enemies.
|
Odd Mushroom
|
121
|
|
DMG up
|
Grants an empty heart container. Increases damage, range and shot height while reducing speed.
|
Odd Mushroom
|
120
|
|
Fire rate up
|
+1.7 tears, +0.3 speed, reduces damage.
|
Ouija Board
|
115
|
|
Spectral tears
|
Grants spectral tears that travel through obstacles (but not enemies) instead of breaking on impact with them.
|
Papa Fly
|
430
|
|
Turret follower
|
A blue fly familiar follows Isaac's movements on a 3 second delay. Papa Fly will fire tears at nearby enemies.
|
The Parasite
|
104
|
|
Split Shot
|
Isaac's tears split in two when they hit something.
|
Pay to Play
|
380
|
|
Money talks
|
+5 coins. Turns all doors that require a single key into doors which need a coin to enter instead. This affects shops, item rooms and libraries.
|
The Peeper
|
155
|
|
Plop!
|
Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to Boom Flies damaging enemies it passes through.
|
Pisces
|
309
|
|
Tears up + knock-back shots
|
-1 Tear Delay, adds knock-back shots and increases tear size.
|
Polyphemus
|
169
|
|
Mega Tears
|
Isaac fires huge tears that deal massive damage but fire rate is greatly decreased. If a tear kills an enemy, the tear travels on with any leftover damage.
|
Proptosis
|
261
|
|
Short range mega tears
|
Tears start out massive with high damage, and then shrink down and become weaker over a short range.
|
Punching Bag
|
281
|
|
Scape Goat
|
Spawns a Mulligan Familiar that will wander the room randomly. Enemies will attack the Mulligan if it's closer.
|
Pupula Duplex
|
379
|
|
Wide shot
|
Gives Isaac spectral tears and gives his tears a wide arc shape, increasing their size.
|
Purity
|
407
|
|
Aura stat boost
|
Boosts one of Isaac's stats depending on the color of the aura around him. The aura disappears upon taking damage and reappears with a random color upon entering a new room. Red boosts damage, blue boosts tears, yellow boosts speed, and orange boosts range.
|
Pyromaniac
|
223
|
|
It hurts so good +5 Bombs
|
Isaac heals 1 heart instead of taking damage from an explosive source. Adds 5 bombs.
|
Pyro
|
190
|
|
99 bombs
|
Adds 99 bombs.
|
Rotten Baby
|
268
|
|
Infested friend
|
A familiar that spawns blue flies.
|
Rubber Cement
|
221
|
|
Bouncing tears
|
Tears bounce off walls, enemies, and environmental objects.
|
Rune Bag
|
389
|
|
Rune generator
|
A bag that follows Isaac and drops a random rune every 5-6 rooms.
|
Sack of Pennies
|
94
|
|
Gives money
|
Isaac is followed by a small bag that drops a coin every 2 rooms.
|
Sacrificial Dagger
|
172
|
|
My fate protects me
|
A dagger orbits Isaac, dealing very high damage and blocking enemy shots.
|
Sad Bombs
|
220
|
|
Tear blast +5 bombs
|
+5 Bombs. Upon exploding, bombs shoot 8 tears off in every direction, similar to Tammy's Head. The tears are affected by any tear modifiers Isaac has on his own tears.
|
The Sad Onion
|
1
|
|
Tears up
|
Increases Tears by 0.7.
|
Sagittarius
|
306
|
|
Penetrative shot + speed up
|
Increases speed by +0.2 and grants piercing tears.
|
Samson's Chains
|
321
|
|
The ol' ball and chain
|
Spawns a ball and chain familiar Isaac pulls behind him that damages enemies, blocks shots, and destroys rocks.
|
Scapular
|
142
|
|
You have been blessed
|
Once per room, when Isaac is reduced to his last half red Heart, the aura around his head temporarily vanishes and he is granted one Soul Heart.
|
Scatter Bombs
|
366
|
|
We put bombs in your bombs!
|
Adds 5 bombs. Isaac's bombs explode into 2-4 tiny bombs.
|
Scorpio
|
305
|
|
Poison tears
|
Grants poison tears, which deal damage over time when inflicted.
|
Serpent's Kiss
|
393
|
|
The kiss of death
|
Tears have a random chance to apply a poison effect to enemies. Isaac now deals poison damage on contact. Enemies that were poisoned have a chance to drop a black heart when killed.
|
Sissy Longlegs
|
280
|
|
She loves you
|
Wanders about the room, occasionally spawning Blue Spiders.
|
Sister Maggy
|
67
|
|
Friends 'till the end
|
A familiar that follows Isaac around shooting blood tears.
|
Smart Fly
|
264
|
|
Revenge fly
|
After Isaac takes damage, this fly will do continuous touch damage to whatever enemy caused the damage until it is dead. The fly will then systematically attack 1 enemy at a time until the room is cleared.
|
The Soul
|
335
|
|
I am all
|
Grants two soul hearts. Isaac gains a pulsing aura that repels enemies and projectiles.
|
Soy Milk
|
330
|
|
DMG Down + Tears Way Up
|
Tears shrink and do much less damage, but fire in very rapid succession.
|
Spider Bite
|
89
|
|
Slow effect
|
Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them.
|
Spoon Bender
|
3
|
|
Homing shots
|
Grants Isaac homing tears.
|
Steam Sale
|
64
|
|
50% off
|
Reduces all Shop prices by 50%, rounded down to 7 coins for an item, rounded up to 2-3 coins for a pickup.
|
Steven
|
50
|
|
DMG up
|
Increases Damage by 1.
|
Sticky Bombs
|
367
|
|
Egg sack bombs!
|
+5 bombs. Bombs stick to enemies and spawn 2-4 Blue Spiders if they kill an enemy.
|
Stigmata
|
138
|
|
DMG + HP up
|
Increases damage, and adds 1 heart container.
|
Strange Attractor
|
315
|
|
Magnetic tears
|
Pickups, trinkets, and monsters are magnetically attracted to Isaac's tears.
|
Taurus
|
299
|
|
Speed down + rage is building
|
Speed down; gains speed while in a room with enemies until gaining My Little Unicorn effect for a few seconds.
|
Tech X
|
395
|
|
Laser ring tears
|
Tears are replaced with laser rings that pierce through enemies and deal damage to enemies within them. Can be charged to increase the size of the ring.
|
Tech.5
|
244
|
|
It's still being tested...
|
Isaac occasionally fires an unlimited range piercing laser alongside his normal tears. The laser can glitch, mimicking the effects of certain items and trinkets.
|
Technology
|
68
|
|
Laser tears
|
Replaces tears with a piercing laser with unlimited range.
|
Technology 2
|
152
|
|
Laser
|
Decreases damage and replaces right eye tears with a unlimited range, piercing laser which fires continuously.
|
Tiny Planet
|
233
|
|
Orbiting tears + range up
|
Range up and makes shot tears revolve around Isaac until they drop.
|
Tough Love
|
150
|
|
Tooth shot
|
Adds a chance to shoot a tooth instead of a tear, which deals greater damage than regular tears.
|
Tractor Beam
|
397
|
|
Control your tears
|
Increases tears, range, and shot speed. Isaac emits a beam from his face that his tears follow along.
|
Virgo
|
303
|
|
You feel refreshed and protected
|
Adds a chance to give a shield that nullifies all incoming damage for 10 seconds upon taking damage. Also converts bad pills into good pills.
|
The Virus
|
13
|
|
Poison touch
|
Inflicts poison to enemies who make contact with Isaac. Speed down. Poisoned enemies have a chance to drop a black heart when killed.
|
The Wafer
|
108
|
|
Damage resistance
|
All sources of damage that would cause more than one-half heart of damage are reduced to one-half heart instead.
|
The Wiz
|
358
|
|
Double wiz shot!
|
Tears simultaneously fire out of both eyes diagonally, similar to the effect of the R U A Wizard? pill. Isaac's tears also travel above all obstacles.
|
Zodiac
|
392
|
|
The heavens will change you
|
Gives Isaac a random zodiac item effect that changes every floor.
|
Adrenaline
|
493
|
|
Panic = power
|
Increases damage based on how many empty Red Heart containers Isaac has.
|
Analog Stick
|
465
|
|
360 tears!
|
+0.3 tears up. Allows Isaac to fire tears diagonally.
|
Apple!
|
443
|
|
Trick or treat?
|
Increases tears. Adds a chance to fire a high-damage razor blade.
|
Backstabber
|
506
|
|
Watch your back!
|
Isaac's tears deal double damage and inflict bleeding on enemies if they're facing away from Isaac.
|
Big Chubby
|
473
|
|
Chub chub
|
Spawns a fat charger familiar that slowly charges forward, blocking shots and damaging enemies in its path.
|
Bloodshot Eye
|
509
|
|
Bloody friend
|
Spawns an orbiting eye familiar that deals contact damage and fires tears every 2 seconds.
|
Bozo
|
513
|
|
Party time!
|
Increases damage by a flat 0.1 and grants a Soul Heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.
|
Brittle Bones
|
549
|
|
Everything hurts
|
Replaces all Red Hearts with 6 empty Bone Hearts. Upon losing a Bone Heart, Isaac fires bones in 8 directions and permanently gains a tears up.
|
Broken Modem
|
514
|
|
Lag!
|
Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals.
|
Camo Undies
|
497
|
|
Camo kid
|
Isaac becomes camouflaged at the beginning of each room. Until he shoots, all non-boss enemies will be confused.
|
Compound Fracture
|
453
|
|
Bone tears!
|
Increases range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle.
|
Cone Head
|
457
|
|
Hard headed!
|
Grants a Soul Heart. Gives Isaac a chance to ignore any damage taken.
|
Contagion
|
466
|
|
Outbreak!
|
The first enemy killed in a room explodes and poisons nearby enemies. Poisoned enemies will also explode upon death.
|
Dead Tooth
|
446
|
|
Halitosis
|
While firing, Isaac gains a green aura that poisons nearby enemies.
|
Depression
|
469
|
|
:(
|
Spawns a cloud familiar that leaves a trail of tears that damages enemies. Has a chance to spawn damaging beams of light onto enemies that touch the cloud.
|
Dog Tooth
|
445
|
|
Bark at the moon!
|
+0.3 damage and +0.1 speed. When Isaac enters a room, a howling sound can be heard if there's a connected secret room, and a barking sound can be heard if there's a crawl space under a rock.
|
Euthanasia
|
496
|
|
Needle shot
|
Adds a chance to fire needles that instantly kill basic enemies and deal triple damage to bosses. If a needle kills an enemy, it bursts into more tears/needles.
|
Eye of Greed
|
450
|
|
Gold tears!
|
Every 20 tears, Isaac loses 1 penny and shoots an additional gold tear that freezes enemies and turns them into gold. Any enemy killed while in this state will drop coins.
|
Finger!
|
467
|
|
Watch where you point that!
|
Spawns a finger familiar that points at enemies, dealing constant damage.
|
Flat Stone
|
540
|
|
Skipping tears
|
Tears bounce off the floor, creating splashes. Splashes deal 25% of Isaac's tear damage to all enemies in a small area.
|
Ghost Pepper
|
495
|
|
Flame tears
|
Adds a chance to shoot a fire that damages enemies and remains in place until it deals enough damage or the room is left.
|
Glaucoma
|
460
|
|
Blind tears!
|
Adds a chance to shoot tears that confuse enemies for an extremely long time.
|
Mom's Wig
|
217
|
|
You feel itchy...
|
Adds a chance to spawn blue spiders when firing tears. Restores 1 red heart.
|
Mongo Baby
|
322
|
|
Mongo Friend
|
Summons a familiar that copies the tears of Isaac's other familiars.
|
Haemolacria
|
531
|
|
I'm seeing red...
|
Tears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay.
|
Hallowed Ground
|
543
|
|
Portable sanctuary
|
Spawns a white poop familiar, which turns into a white poop when Isaac is hurt. White poop has an aura that halves tear delay and can block enemy shots.
|
Hushy
|
470
|
|
Lil hush!
|
Spawns a Hush familiar that bounces around the room and deals contact damage. While firing tears, it stops moving.
|
Jacob's Ladder
|
494
|
|
Electric tears
|
Tears fire sparks of electricity in random directions upon hitting an obstacle or enemy.
|
Rainbow Baby
|
174
|
|
Random buddy
|
Spawns a familiar that follows Isaac around and fires tears with random effects.
|
The Relic
|
98
|
|
Soul generator
|
Isaac is followed by a small blue cross that will drop a Soul Heart every 5-6 rooms.
|
Robo-Baby
|
95
|
|
Friends 'till the bbbbzzzt
|
Follows Isaac around, shooting enemies with an eye laser similar to Technology.
|
Robo-Baby 2.0
|
267
|
|
We worked out all the kinks
|
Fires lasers at any enemy in its line of sight and moves based on the direction Isaac is firing tears.
|
Jaw Bone
|
548
|
|
Fetch!
|
Spawns a familiar that flies the room while firing, dealing a flat 7 damage to enemies that come in contact and retrieving pickups.
|
Jumper Cables
|
520
|
|
Bloody recharge
|
Grants an active item charge every 15 enemies killed.
|
Lachryphagy
|
532
|
|
Feed them!
|
Isaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage.
|
Large Zit
|
502
|
|
Creep shots
|
Adds a chance to fire a creep shot that deals double damage and leaves a trail of slowing white creep.
|
Lead Pencil
|
444
|
|
He's a bleeder!
|
After every 15 tears fired, Isaac will fire a high-damage cluster of tears.
|
Leprosy
|
525
|
|
You're tearing me apart!
|
Upon taking damage, grants a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with. The orbitals will be destroyed if they take enough damage from enemies or enemy shots.
|
Lil Monstro
|
471
|
|
Ain't he cute?
|
Spawns a familiar that fires clusters of tears. Must be charged before shooting.
|
Lil Spewer
|
537
|
|
Puking buddy
|
Spawns a random pill, and grants a small Spewer familiar that charges up and fires creep. Using pills changes the creep type.
|
Linger Bean
|
447
|
|
Crying makes me toot
|
Constantly shooting causes Isaac to release gas clouds that can be pushed by his tears and damage nearby enemies.
|
Little Horn
|
503
|
|
Science!
|
Adds a chance to fire a piercing tear that instantly kills any enemy that it touches.
|
Match Book
|
344
|
|
Evil up
|
Grants Isaac 1 Black Heart and 3 bombs. Can also give troll bombs.
|
Metal Plate
|
449
|
|
It itches...
|
Grants one soul heart. Enemy shots have a chance to be reflected at the shooter as confusing tears.
|
Mom's Razor
|
508
|
|
It's sharp!
|
Spawns an orbiting razor that damages enemies it touches and inflicts bleeding on enemies, causing them to slowly take damage over time.
|
Mystery Egg
|
539
|
|
Sacrificial insemination
|
Spawns an egg familiar, which cracks and turns into a random friendly enemy when Isaac is hurt. The egg regenerates upon entering a different room.
|
Parasitoid
|
461
|
|
Egg tears!
|
Adds a chance to fire an egg sack which spawns slowing creep and spawns a blue fly or spider upon hitting an enemy.
|
Pointy Rib
|
544
|
|
Stabbing time
|
Spawns a bone familiar that can be aimed with the fire buttons and does contact damage.
|
Pop!
|
529
|
|
Eyeball tears!
|
Replaces Isaac's tears with eyeballs that can bounce off of each other. The eyeballs are not limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle.
|
Shard of Glass
|
448
|
|
Blood and guts!
|
Upon taking damage, Isaac has a chance to drop a full red heart, gain 5 range, and leave a trail of damaging red creep for the current room.
|
Sinus Infection
|
459
|
|
Booger tears!
|
Adds a chance to fire a booger that sticks to enemies and deals damage over time.
|
Slipped Rib
|
542
|
|
Projectile shield
|
Spawns a bone familiar that circles around Isaac and reflects enemy shots.
|
Sulfuric Acid
|
463
|
|
Acid tears!
|
+0.3 damage. Adds a chance to fire acidic tears which can destroy obstacles.
|
Technology Zero
|
524
|
|
Static tears!
|
Connects Isaac's tears with electricity that can damage enemies.
|
Varicose Veins
|
452
|
|
I'm leaking...
|
Taking damage releases a ring of 10 high damage tears.
|