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Item icon
Item altar
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Character appearance

Tear appearance
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(page 5, column 8, row 3)
Added in Afterbirth †

Trisagion is an unlockable passive item added in Booster Pack #4.

Effects[edit | edit source]

  • Tears are replaced with piercing white blasts of light.
    • Blasts deal 33% of the regular tear damage but can hit the same enemy multiple times.
    • Blasts do not knockback enemies.

Notes[edit | edit source]

  • Since the blasts can strike one enemy multiple times, low shot speed can be very beneficial whereas high shot speed may lower effective damage.
    • Walking backward while firing can allow tears to move slower, making it useful for increasing damage output.

Synergies[edit | edit source]

  • 8 Inch Nails 8 Inch Nails / Blister Blister / Pisces Pisces: Adds knockback to blasts, which can not only significantly repel enemies when used correctly, it can deal a high amount of damage to enemies unable to escape the knockback.
  • Chocolate Milk Chocolate Milk: Fully charged Trisagion blasts deal 4 times more damage, exceeding Isaac's tear damage.
  • Evil Eye Evil Eye: Eyes will fire beams. Occasionally causes Trisagion beams to stay static in the air for a few seconds, dealing damage to enemies that come in contact with them.
  • Godhead Godhead: Although the damaging aura isn't visible, it still exists and is not affected by Trisagion's damage reduction.
  • Guppy (Transformation): As it hits multiple times, it spawns multiple flies per tear making it very strong.
  • Haemolacria Haemolacria: Both Trisagion and Haemolacria fire at the same time, Haemolacria does not keep spectral tears despite its tears sprite change but the arced tear keeps piercing.
  • Homing Tears: Tears slow down and stay on top of the enemy, doing continuous damage.
  • Ipecac Ipecac: Beams will now travel through obstacles and maintain their piercing effect dealing 33% of regular damage to enemies they come in contact with, but won't explode on hit. The Ipecac explosion will happen once the beam runs out of range or hits a wall and will deal damage equal to Isaac's damage.
  • The Ludovico Technique The Ludovico Technique: The beam becomes controllable, still dealing reduced damage but at a very high rate.
  • My Reflection My Reflection: In addition to the usual effect, lengthens the Trisagion blasts into short flexible beams for a much larger damage-dealing area.
  • Mysterious Liquid Mysterious Liquid: Causes a large trail of creep. The effect stacks, which causes heavy damage (even to Hush).
  • Proptosis Proptosis: Base damage is doubled and beam damage is boosted to about 65%. Blasts lose no power as they travel further, though the tips of the blasts deal very slightly less damage.

Interactions[edit | edit source]

  • Azazel: Azazel's short-range Brimstone overrides Trisagion.
  • Brimstone Brimstone: Overrides Trisagion.
  • Cricket's Body Cricket's Body/Compound Fracture Compound Fracture/The Parasite The Parasite: Split blasts are not generated on hitting enemies, only on obstacles and walls, as well as floors for Cricket's Body.
  • Dead Eye Dead Eye: Overridden by Trisagion.
  • Dr. Fetus Dr. Fetus: Overrides Trisagion.
  • Epic Fetus Epic Fetus: Overrides Trisagion.
  • Eye of Belial Eye of Belial: Overridden by Trisagion.
  • Euthanasia Euthanasia: Overridden by Trisagion.
  • Flat Stone Flat Stone: Blasts continually disappear and reappear as they "bounce". The bounces deal 25% splash damage based on Isaac's base rating, but the blasts cannot do their damage while they're disappearing, leading to an overall reduced efficiency.
  • Holy Light Holy Light: Overridden by Trisagion.
  • Jacob's Ladder Jacob's Ladder: Electric arcs are not generated on hitting enemies, only on obstacles and walls.
  • Lachryphagy Lachryphagy: The blasts will slow down and float like Lachryphagy tears and eventually burst, but can not consume each other.
  • A Lump of Coal A Lump of Coal: Nearly no effect; increases damage by around 5% when the hit is dealt by the tip of the blast.
    • A Lump of Coal + My Reflection: As the beam is longer, the amount of extra damage at the tip can be up to around 50%.
  • Mom's Knife Mom's Knife: Overrides Trisagion.
  • Multidimensional Baby Multidimensional Baby: The baby cannot duplicate Trisagion blasts.
  • Nose Goblin Nose Goblin: Overridden by Trisagion.
  • Parasitoid Parasitoid: Overridden by Trisagion.
  • Pop! Pop!: The blasts will slow down and float like Pop! tears, but will not bounce off each other.
  • Sinus Infection Sinus Infection: Overridden by Trisagion.
  • Tech X Tech X: Overrides Trisagion.
  • Technology Technology: Overrides Trisagion.
  • Technology Zero Technology Zero: Unless Isaac has shooting familiars, Technology Zero will not function. Familiars' tears will be connected to the blasts with electricity, however.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Trisagion is based on this Steam Workshop item by x Wyvern x and TRPG, originally known as Lightshot.
  • The name is a reference to one of the oldest Christian hymns.

Gallery[edit | edit source]

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