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Universal (Bosses)

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Bosses
Chapter 1 Chapter 2 Chapter 3 Chapter 4 Added in Afterbirth  Blue Womb Chapter 5 Chapter 6 Added in Afterbirth †  The Void
Universal Devil and Angel Room Seven Deadly Sins Added in Afterbirth  Greed Mode All Mini-Bosses All Bosses

Universal[edit | edit source]

Universal Bosses are those which may appear at the end of floors 1-5 and 7, replacing a boss from the pool for that environment.

Boss The Fallen.png
Boss The Headless Horseman.png
The Fallen Requires previous entry into a devil room The Headless Horseman Needs to be unlocked


Bosses Boss Monstro.png
Chapter 1
Stage The Basement icon.pngStage The Cellar icon.pngStage Burning Basement icon.png
Blighted OvumDingleThe Duke of FliesFamineFistulaGeminiGurglingsThe HauntLarry Jr.MonstroPinStevenWidowThe FallenThe Headless Horseman
Added in Afterbirth DangleLittle HornRag ManTurdlings
Chapter 2
Stage The Caves icon.pngStage The Catacombs icon.pngStage Flooded Caves icon.png
Carrion QueenC.H.A.D.ChubDark OneGurdyGurdy Jr.The HollowThe HuskMega FattyMega MawPeepPestilencePolycephalusThe WretchedThe FallenThe Headless Horseman
Added in Afterbirth The ForsakenThe FrailThe Stain
Added in Afterbirth † Big HornRag Mega
Chapter 3
Stage The Depths icon.pngStage Necropolis icon.pngStage Dank Depths icon.png
The AdversaryThe BloatThe CageThe GateGishLokiMask Of InfamyMonstro IIWarThe FallenThe Headless HorsemanMom
Added in Afterbirth Brownie
Added in Afterbirth † Sisters Vis
Chapter 4
Stage The Womb icon.pngStage Utero icon.pngStage Scarred Womb icon.png
BlastocystThe BloatConquestDaddy Long LegsDeathLokiiMama GurdyMr. FredScolexTeratomaTriachnidThe FallenThe Headless HorsemanMom's HeartIt Lives
Added in Afterbirth † Sisters VisThe Matriarch
Added in Afterbirth Blue Womb
???
Added in Afterbirth Hush
Chapter 5
Stage Sheol icon.pngStage Cathedral icon.png
SatanIsaac
Chapter 6
Stage Dark Room icon.pngStage The Chest icon.png
???The LambMega Satan
Added in Afterbirth † The Void
Stage The Void icon.png
Added in Afterbirth † Delirium
Added in Afterbirth Greed Mode
Ultra Greed
Added in Afterbirth Ultra Greed
Added in Afterbirth † Ultra Greedier
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