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Font TeamMeat V.pngFont TeamMeat i.pngFont TeamMeat r.pngFont TeamMeat g.pngFont TeamMeat o.png
Item icon
Item altar
Table dividing line 1.png
Character appearance
Table dividing line 2.png
Treasure Room Treasure Room
Greed mode only Treasure Room Treasure Room
Table dividing line 3.png
Added in  Afterbirth(page 3, column 18, row 3)
Removed in Afterbirth(page 3, column 8, row 10)

Virgo is a passive Zodiac item.

Effects[edit | edit source]

  • Grants a chance to trigger the Book of Shadows Book of ShadowsBook of Shadows Icon.png3 roomsUpon use, creates a protective shield nullifying all types of damage for 10 seconds. effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
    • The activation chance depends on the Luck stat, and goes up to 100% with 10 Luck.
  • Converts all stat down pills into stat up pills, "Bad Trip" into "Balls of Steel" and "Amnesia" into "I Can See Forever", like PHD PHDPHD Icon.pngConverts all bad pills into good pills, spawns one pill pickup and restores health. Identifies all pills upon pickup. does, but does not identify any pill.

Synergies[edit | edit source]

  • Mom's Bottle of Pills Mom's Bottle of PillsMom's Bottle of Pills Icon.png6 roomsGives Isaac a random pill, and will cause him to drop any held Q-slot item (If any). The player will only receive six different pill types in one playthrough.: Generated pills are more beneficial.
  • Safety Cap Safety CapSafety Cap Icon.pngImproves the chance of Pills dropping after clearing a room, and chance of finding a Pill when opening a Chest./Little Baggy Little BaggyLittle Baggy Icon.pngIsaac can hold 2 pills at once and all cards are replaced by pills.: Beneficial pills can be found more often.

Notes[edit | edit source]

  • The shield negates health loss from Blood Donation Machines and Devil Beggars.
  • Does not prevent heart container loss from Devil Room deals.
  • The following pill types are neutral and do not have a "good" equivalent.
    • "Hematemesis".
    • "Explosive Diarrhea".
    • "I found pills".
    • "Paralysis".
    • "R U A Wizard".
    • "Telepills".
  • Bad pills already obtained/dropped will be converted to their "good" counterpart too.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • This item, like the other Zodiac items, is a reference to Zodiac signs.

Seeds[edit | edit source]

 PC  K0TA K2ZC (Treasure room adjacent to spawn)

 PC  QWNA GPLP (Treasure room adjacent to spawn)

 PS4  6N2H LQ49 (Treasure room adjacent to spawn)

 Vita  HEAJ 1T43 (Treasure room adjacent to spawn)

 Switch  Greed mode only GF08 T1GR (First Golden Treasure Room)

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