When Life Gives You Lemons

Isaac     9 VoltReduces the charge of any Activated Items by 1. Any 1 charge items instead have timed recharges. HabitWhen Isaac is hit, 1 point of an item's charge is filled. Lemon MishapCreates a small yellow pool of creep, which damages enemies that cross it. 1 Lemon Party pill   : no          : yes Card Against HumanityComplete challenge #12

When Life Gives You Lemons is Challenge #12. You start off with Lemon MishapCreates a small yellow pool of creep, which damages enemies that cross it., 9 VoltReduces the charge of any Activated Items by 1. Any 1 charge items instead have timed recharges., HabitWhen Isaac is hit, 1 point of an item's charge is filled. and 1 Lemon Party pill. Your goal is to defeat Mom. This Challenge is available by default. Treasure rooms are not present.

Difficulty

The lack of Treasure Rooms makes the challenge more difficult than a normal run.

Strategy

• Lemon MishapCreates a small yellow pool of creep, which damages enemies that cross it. has a small range, making it difficult to use. The HabitWhen Isaac is hit, 1 point of an item's charge is filled. and 9 VoltReduces the charge of any Activated Items by 1. Any 1 charge items instead have timed recharges. will allow you to use it often, but their combination is more important than that. Because you have the 9 VoltReduces the charge of any Activated Items by 1. Any 1 charge items instead have timed recharges., any activated item you get will take less time to recharge. The HabitWhen Isaac is hit, 1 point of an item's charge is filled. makes taking damage charge it faster as well. The only catch would be finding a better activated collectible.
• The Lost Cork is an extremely beneficial trinket in this run, expanding the area of Lemon Mishap and thus making it safer to use since Isaac doesn't need to be as close to the enemy.
• A good item to find is Shoop Da Whoop!Fires a laser from Isaac's mouth., which is usable every room because of 9 VoltReduces the charge of any Activated Items by 1. Any 1 charge items instead have timed recharges..

Reward

• 

  Card Against Humanity - Complete challenge #12.

Trivia

• The challenge name is a reference to the proverbial phrase "When life gives you lemons, make lemonade."
• One of the fortune teller's fortunes is "When life gives you lemons, reroll!"