XXXXXXXXL is Challenge #21. This challenge changes all floors to be the size of XL Womb, but does not combine the floors of each chapter. The goal is to defeat Mom's Heart/ It Lives.
Due to the floors being much bigger, it makes important rooms like Treasure Rooms and Shops take significantly longer to find, which can make the run difficult if Isaac has rather weak items. It also makes Secret and Super Secret Rooms much harder to find. Despite the fact that all floors are technically XL, there is only one treasure and boss room on each floor. On the plus side, since there are more rooms, there are more opportunities to generate pickup items.
- Items and pickups that reveal the map are very crucial, allowing easy maneuvering between Special Rooms throughout floors.
- Teleportation cards, such as The Stars and The Hermit, are very valuable, as they allow easy access to Special Rooms. The Emperor is especially powerful, as it can be used to skip the entirety of a floor.
- Avoid items that teleport Isaac at random, such as Cursed SkullIf Isaac has less than one full red heart after taking damage, he will be immediately teleported to the last cleared room he was in., as they can significantly slow down progress by potentially teleporting him to the other side of the map. Picking up the Cursed EyeGrants charged tears that can be fired in a tight burst of four. Getting hit while charging will teleport Isaac into another room. is not recommended for the same reasons.
| Mom Unlocks
|The WombDefeat Mom for the 1st timeThe HarbingersDefeat Mom for the 1st timeA Cube of MeatDefeat Mom for the 1st timeA HaloDefeat Mom using The BiblePuristDefeat Mom for the first time
||XXXXXXXXLDefeat Mom for the 1st timeSPEED!Defeat Mom for the 1st timeHave a HeartDefeat Mom for the 1st timePRIDE DAY!Defeat Mom for the 1st timeOnan's StreakDefeat Mom for the 1st timeThe GuardianDefeat Mom for the 1st time
||Aprils foolDefeat Mom for the 1st time