Binding of Isaac: Rebirth Wiki
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???'s Only Friend is an unlockable passive item.

Effects

Notes

  • Unlike Collectible The Ludovico Technique iconThe Ludovico Technique, it cannot be controlled with the mouse, even with mouse control enabled.
  • Holding two opposite fire keys (both left and right or both up and down) at the same time will keep the familiar in place, while making Isaac fire in the direction of whichever fire key was pressed second.
    • This can help during combats with bosses who do not move a lot, as the familiar can continuously damage the boss when kept stationary.
    • On some keyboards, holding opposite fire keys may cause other keys to become unresponsive.

In-game Footage

Seeds

PC Normal mode only HC7F QZAT (Treasure Room adjacent to spawn)

PC Normal mode only J6S4 VMQM (Treasure Room adjacent to spawn)

PC Hard mode only 6CQZ CL2Y (Treasure Room adjacent to spawn)

PC (in Afterbirth † and Repentance) Normal and hard modes only 0CN2 GSH1 (Treasure Room adjacent to spawn)

PS4 Y4FW NYCX (First floor treasure room)

Switch Greed mode only 6RS1 FT1H (First Golden Treasure Room)


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