Best Friend is an activated item.
Effect[ | ]
- Spawns a decoy vaguely resembling Isaac in his crying animation, which explodes after 5 seconds with the blast radius of a
Mega Troll Bomb.
- The decoy bomb distracts enemies, as they will target the decoy instead of Isaac regardless of distance.
The explosion deals 110 
The explosion deals 185 Notes[ | ]
- All Bomb modifier items will affect Best Friend, with the exception of Bobby-Bomb, Bomber Boy, Fast Bombs, Mr. Mega, and Rocket in a Jar.
- Scatter Bombs will create mini decoys.
- Bosses such as Chub or Carrion Queen can swallow the decoy bomb just like a regular bomb.
- Isaac can push the decoy bomb by walking into it or shooting it with his tears just like regular bombs.
Synergies[ | ]
- Book of Virtues: Creates wisps that are small Isaac heads with a white flame in the middle ring. Tears shot by these have a 7.5% of applying the mark status effect, akin to Rotten Tomato.
- Car Battery: Spawns two decoys on top of each other.
- Remote Detonator + Schoolbag: The decoy bomb is affected by remote detonator.
In-game footage[ | ]
Trivia[ | ]
- Edmund McMillen stated that Best Friend would no longer "Die upon touch". This is a reference to a bug in the original The Binding of Isaac where, in many circumstances, Isaac could take glitched hits (often killing Isaac outright).
- Best Friend works remarkably similar to Pipe Bombs in Left 4 Dead, down to the 5 second timer and not working on bosses.
Gallery[ | ]
The icon of Best Friend as seen on the lower 3DS screen.
Best Friend when deployed onto the ground.
Bugs[ | ]
 Bug!
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Gurgles, Splashers, Boils, Guts, and Sacks are immune to Best Friend's explosion. |
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| Bug!
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Switch Doubles when Multidimensional Baby passes through it.[citation needed] |
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 The Binding of Isaac: Rebirth
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