Binding of Isaac: Rebirth Wiki
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Book of Shadows is an activated item.

Effect

  • Upon use, creates a protective shield nullifying all types of damage for 10 seconds.

Notes

  • The Book of Shadows effect negates health loss from Blood Donation Machines and Devil beggars.
  • Does not prevent heart container loss from Health Down Pills or Devil room deals.
  • The Book of Shadows is highly effective with orbital familiars because the player can run into enemies and deal a massive amount of damage.
  • Collectible Razor Blade iconRazor Blade can be used at no cost while the Book of Shadows shield is present, allowing damage to be significantly increased for the room.
  • In Rebirth, The Book of Shadows and other invulnerability items will no longer grant drops from the sacrifice room.
  • The effect ends if the player leaves the room.

Synergies

In-game Footage

Gallery

Trivia

  • The Book of Shadows is a reference to the infamous Book of Shadows, a book of religious texts and instructions for magical rituals found within the Neopagan religion of Wicca.

Seeds

PC 4AP4 J07H (First floor treasure room, north of spawn; Curse of the Unknown)

PS4 VZFS Z60W (First floor treasure room)

Vita CBWE 162X (Treasure room adjacent to spawn)

3DS TRKL JDCG (First floor treasure room)

Switch Normal mode only 7ENY AQRB (First Floor Treasure Room)


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