There are two types of Challenge Rooms. They will only spawn on a floor if, upon entering the floor, Isaac's total health is greater than or equal to his number of heart containers.
Normal Challenge Room
Can only be entered if Isaac's total health (red, black, and soul hearts) is greater than or equal to his number of heart containers.
Picking up its contents will spawns 3 waves of enemies when opened. While in Chapter 4 (Womb/Utero), 3 waves of bosses will be spawned (usually bosses from Basement/Caves).
Each wave cleared will charge Isaac's active item by 1.
A Challenge Room can contain:
- 1 or 2 Chests / Golden Chests / Red Chests
- 3 Red Chests
- 1 Chest + 1 Golden Chest + 1 Red Chest
- A random item from Treasure Room pool.
The enemies that spawn depend on the current chapter, and each chapter has two different possible sets of enemies:
Floor | Wave 1 | Wave 2 | Wave 3 |
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The Basement | 3 Hoppers | 3 Horfs | 2 Clotties |
5 Attack Flies | 5 Pooters | 4 Gapers | |
The Cellar | 3 Fattys | 3 Round Worms | 5 Dips |
3 Gapers | 3 Horfs | 3 Fatties | |
The Caves | 5 Chargers | 4 Globins | 4 Maws |
5 Spitties | 3 Hives | 3 Hosts | |
The Catacombs | 2 Bonies | 2 Tumors | 3 Wall Creeps |
4 Round Worms | 3 Nightcrawlers | 1 Grub | |
The Depths | 3 Vis | 4 Leapers | 4 Globins |
4 Babies | 5 Hoppers | 4 Knights | |
Necropolis | 4 Knights | 3 Mom's Hands | 3 Fat Sacks |
4 Bonies | 2 Squirts | 3 Nulls | |
The Womb Cathedral Utero Sheol |
3 Larry Jrs | Chub and 3 Chargers | 2 Monstros |
Fistula | Loki | Chub |
Notes
- The three waves appear in random orders rather than the orders listed above.
- If Isaac has some way to teleport out of the room, the contents of the Challenge Room can be taken without fighting the enemies.
- If a Secret Room is next to a Challenge Room, it can be entered by using a bomb in the Secret Room on the wall separating the two rooms. However, the entrance to the Secret Room from the Challenge Room closes itself, meaning Isaac cannot escape through the Secret Room entrance.
- If Spiders had spawned from the red chest before the enemy waves had started, the spiders have to be killed in order for the waves to start.
- If Spiders had spawned from the Red Chest after the enemy waves are over, the player may choose to leave the room without having to fight them.
Boss Challenge Room
Boss Challenge Rooms can only be entered if Isaac has one or less red heart. Its contents are similar to the normal Challenge Room, but there is a chance it will contain an item from the Boss Item Pool.
After opening a chest or taking a pedestal item inside the room, a boss will spawn. After beating the first boss, a second will spawn.
Each wave cleared will charge Isaac's active item by 1.
The bosses that spawn depend on the current chapter. Alternate floors have two possible sets of bosses that could spawn:
Notes
- In Chapter 4 and beyond, the bosses spawned in the Boss Challenge Room are the same as those spawned in the standard Challenge Room.
- If a Secret Room is next to a Boss Challenge Room, it can be entered by using a bomb in the Secret Room on the wall separating the two rooms. However, the entrance to the Secret Room from the Boss Challenge Room closes itself, meaning Isaac cannot escape through the Secret Room entrance.
- Because of the health requirements, both types of Challenge Room will always be open for The Lost and Blue Baby.
- Like the Challenge Room, Spiders have to be killed if they come out of Red Chests before the boss waves start.
Bugs
Bug! | If the game crashes or you close it before you finish the challenge room it will crash every time you try to continue that run. |
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Rooms | ||||||
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Unlocked | Boss Room |
Mini-Boss Room |
Curse Room |
Sacrifice Room |
Closet |
Grave Room |
Locked | Treasure Room |
Shop |
Library |
Planetarium |
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Slotted | Arcade |
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Barred | Challenge Room |
Boss Challenge Room |
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Double-locked | Vault |
Dice Room |
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Double-boarded | Clean/Dirty Bedroom |
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Hidden | Secret Room |
Super Secret Room |
Crawl Space |
Black Market |
I AM ERROR |
Ultra Secret Room |
Post-boss | Devil Room |
Angel Room |
Boss Rush |
Blue Womb Entrance |
The Binding of Isaac: Rebirth |
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