Charm of the Vampire is a passive item.
Effects[ | ]
- Restores a
Half Red Heart for every 13 enemies killed. - +0.3 damage.
+0.3 Notes[ | ]
- As Keeper and Tainted Keeper, coin hearts can be restored with this item.
- The healing effect is useless for characters that cannot use Red hearts.
- Tainted Bethany will gain one blood charge when it activates.
- Shopkeepers count as an enemy.
- This item removes Isaac's reflections in the water/blood visible in some floors.
- The healing counter also applies to enemies killed by familiars.
As 
Interactions[ | ]
- Freeze Effects: Enemies that die from being frozen don't count towards the healing counter.
- Maggy's Bow: No effect.
- My Reflection: Despite vampires having no reflection, Charm of the Vampire does not remove the effect of My Reflection.
- Tainted Magdalene: Restores a full Red Heart instead.
In-game Footage[ | ]
Trivia[ | ]
- Prior to Repentance, this item's description was "Kills heal"
- If the player clears out a room and saves at least one enemy, they can save, quit, and then continue the run to enter the same room with enemies reset. The counter for Charm of the Vampire is saved along with the game, meaning the player can farm the same room for Red Hearts.
- This item is used in Have a Heart (challenge #25).
- A vampire is a being from folklore who subsists by feeding on the life essence (generally in the form of blood) of the living.
- In folklore, a vampire leaves no reflection because it has no soul. This is why Charm of the Vampire removes Isaac's reflection.
- In folklore, a vampire leaves no reflection because it has no soul.
- If the player dies while one of their tears is on track to kill an enemy (or by killing a weak enemy using contact damage), Charm of the Vampire can heal the player for half a heart while the player is in the process of dying, leaving the player dead with half a Red Heart.
Prior to Repentance, this item's description was "Kills heal" The Binding of Isaac: Rebirth
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