Closets are rare, small, dead end rooms added in The Binding of Isaac: Afterbirth. Closets often contain a unique arrangement of objects, pickups, items, or enemies, but are otherwise identical in appearance to normal rooms. Each chapter has a different set of 9-10 closet layouts.
The Basement
- 3 buttons
- A trapdoor to the next floor
- Rag Man
- A yellow Ragling spawns instead as of Booster Pack #5.
- A bed
- A gold bomb surrounded by TNT
- Lots of urns
- A golden poop and 5 regular piles of poop
- 5 suction pitfalls and 3 red chests
- 3 mega troll bombs and 4 black flies
- A golden key and 2 random pickups behind key blocks
- Several Blue Gapers surrounded by rocks
- A Golden Chest, 4 fireplaces and 2 urns
The Cellar
- 3 buttons
- A bomb bum
- A Black Globin's Head and a Black Globin's Body
- A bed
- A gold bomb surrounded by TNT
- Lots of urns
- A golden poop and 5 regular piles of poop
- 5 suction pitfalls and 3 red chests
- 3 mega troll bombs and 4 spiders
- A golden key and 2 random pickups behind key blocks
The Caves
- A trapdoor to the next floor
- 5 dips surrounded by poop
- 6 coins and a Donation Machine
- 6 coins and a Shell Game Beggar
- 3 piles of black poop, a black heart, and a Devil Beggar
- 3 buttons
- 3 Dark Balls
- A shopkeeper and 18 black flies
- Lots of mushrooms
- A normal beggar and a black fly surrounded by troll bombs
- 5 Bomb Bums surrounded by 12 fireplaces and 6 red fireplaces
The Catacombs
- A trapdoor to the next floor behind spikes
- 5 troll bombs surrounded by poop
- A shopkeeper and an angel chest
- 6 coins and a Shell Game Beggar
- 3 piles of black poop, a black heart, and a Devil Beggar
- 2 buttons, one behind spikes
- 8 boils
- A shopkeeper and 18 black flies
- Lots of mushrooms and poop
- A normal beggar and a black fly surrounded by troll bombs
The Depths
- 5 shopkeepers and a random item from the treasure room pool
- 9 keys arranged in the shape of a key
- A troll bomb surrounded by skulls
- 3 buttons, a trapdoor to the next floor, and an I AM ERROR shopkeeper
- A bed
- 8 golden chests behind key blocks
- Polycephalus
- 3 piles of golden poop behind spikes
- One pile of each type of poop
- 4 Chubs at the bottom of the room and a hanging shopkeeper in the center
- 9 Angel Chests surrounded by 5 Purple Fireplaces
Necropolis
- 5 shopkeepers and a random item from the treasure room pool
- 9 keys arranged in the shape of a key
- A troll bomb surrounded by skulls
- 2 buttons, a sack, a trapdoor to the next floor, and an I AM ERROR shopkeeper
- A bed
- 8 golden chests behind key blocks
- A medium-sized Teratoma
- 3 piles of golden poop behind spikes
- One pile of each type of poop
The Womb
- 19 boils
- 6 boils and 6 brown chests behind key blocks
- 2 Gluttonies
- 3 spike chests behind spikes and retractable spikes
- 8 keys and an angel chest
- 4 Blood Donation Machines surrounded by lots of Embryos and red hearts
- 4 I - The Magician cards surrounded by rocks
- 2 Gurglings
- A button
- A random item from the treasure room pool behind lots of red poop
Utero
- 19 boils
- 6 boils and 6 brown chests behind key blocks
- 2 Bloodshot Eyes behind spikes
- 3 spike chests behind spikes and retractable spikes
- 8 keys and an angel chest
- 4 Blood Donation Machines surrounded by lots of Embryos and red hearts
- 4 I - The Magician cards surrounded by rocks
- Lokii and a Heart
- A button
- A random item from the treasure room pool behind lots of red poop
- 4 Blood Donation Machines, 3 Flesh Death's Heads, and 2 piles of red poop
Cathedral
- A normal beggar, a bomb bum, a key Master, and a devil beggar
- 9 blue fireplaces
- Uriel
- Gabriel
- 3 piles of rainbow poop
- 5 buttons
- 8 keys and an angel chest
- 7 Psychic Maws
- Urns and spikes
- 5 blue/purple fireplaces
Sheol
- A bomb bum and 2 devil beggars
- A trapdoor
- TNT surrounded by skulls
- 5 spike chests
- Little Horn
- 3 black hearts and 3 Imps
- 3 black hearts behind a troll bomb and 3 mega troll bombs
- 5 buttons behind spikes
- 24 spiders
- 4 buttons and 3 suction pitfalls
The Chest
Not all closets in The Chest are dead-end rooms.
- A room filled with red poop and 2 1+1 free hearts
- A pile of rainbow poop
- 6 buttons
- 8 brown chests and an angel chest
- 8 pills
- 2 Greeds
- 2 Lusts
- 36 coins
- 9 gold bombs
- 6 random pickups
Dark Room
- 3 devil beggars
- 5 red chests
- 3 II - The High Priestess cards
- 4 Begottens
- 3 eternal hearts
- 3 sacks
- 31 dimes
- 3 spike chests
- 4 mega troll bombs and an Imp
- 4 black hearts