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From Binding of Isaac: Rebirth Wiki
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Effects are a major mechanic of The Binding of Isaac: Rebirth. They can alter the behavior of Monsters and Tears, and can be beneficial or harmful in some way to Isaac.

Confusion Effect.png
Spoon Bender Tears.png
Book of Shadows App.png
Fate App.png
Status Effects Tear Effects Temporary Buffs Player Effects

The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item Pools Item Pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets