Eye of Greed is an unlockable passive item added in Afterbirth †.
Effects
- Adds a golden tear every 20 tears fired, which causes enemies to turn gold and freeze for a few seconds (similar to
Midas' Touch) at the cost of one penny. Golden tears can still be fired if Isaac has no money.
- Unlike other tear effects, golden tears are fired alongside regular tears rather than replacing a regular tear.
- With multi-shot abilities, whichever tear is the 20th since previous will produce the additional golden tear.
- The golden tear deals 2x normal damage.
- Enemies killed while golden will drop 1-4 pennies.
Interactions
- Brimstone: Overrides Eye of Greed.
- Diplopia: No effect.
- Dr. Fetus: Overrides Eye of Greed.
- Epic Fetus: Overrides Eye of Greed.
- Flat Stone: Golden tear does not bounce.
- Lost Contact: Golden tears will not block shots.
- The Ludovico Technique: Overrides Eye of Greed.
- Mom's Knife: Overrides Eye of Greed.
- Technology: Overrides Eye of Greed.
- Tech X: Overrides Eye of Greed.
Synergies
- 20/20/The Inner Eye/Mutant Spider: The additional tears will lessen the amount of times tears need to be fired before a golden tear is fired. Only one golden tear is fired each time.
- Analog Stick: Golden tears can be fired diagonally.
- Angelic Prism: Golden tears will quadruple when passing through the prism.
- Chocolate Milk: How much the 20th tear was charged determines the size and damage of the golden tear.
- Compound Fracture: Golden tears will still look like coins and will still split into other golden coins when hitting obstacles.
- Continuum: Golden tears will travel through walls.
- Cricket's Body/The Parasite: Golden tears will split when fired.
- Cupid's Arrow: Golden tears will retain piercing effect.
- Cursed Eye: Each tear fired counts towards the 20 required, so Isaac only has to fire 5 fully charged bursts for a golden tear to appear. Golden tears are not multiplied.
- Dead Eye: Golden tear damage increases with accuracy.
- Explosivo: Golden tears have a chance to stick to enemies and grow.
- Godhead: Golden tears will have damaging aura and homing effect.
- Haemolacria: Fires giant golden tears with 31% damage increase.
- Ipecac: Will occasionally fire explosive golden tears.
- Lachryphagy: Golden tears can also be fed and will burst into split tears. Burst tears are not golden.
- A Lump of Coal: Golden tears will grow in size and damage as they travel.
- Marked: Golden tears will fire in whichever direction the crosshair is.
- Monstro's Lung: Each tear in the burst counts towards the 20 required. Without other items that increase the number of tears fired, two out of every three bursts will fire a golden tear.
- Mysterious Liquid: Golden tears will create green creep when they hit something.
- Pop!: Golden tears can be knocked around by other tears.
- Proptosis: Golden tears will shrink with distance.
- Pupula Duplex: Golden tears are much bigger and retain spectral effect.
- My Reflection: Golden tears will return to Isaac.
- Ouija Board: Golden tears will retain spectral effect.
- Rubber Cement: Golden tears will bounce off walls.
- Spoon Bender: Golden tears will home in on enemies.
- Technology Zero: Golden tears will connect to other tears with electricity.
- Tiny Planet: Golden tears will orbit Isaac.
- Trisagion: Adds an extra beam with golden tear effects every 20th shot.
In-game Footage
Seeds
PC 
MPCB QY0C (First Golden Treasure Room)
Switch 6GW8 CG48 (First Golden Treasure Room)
 The Binding of Isaac: Rebirth
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