Leprosy is an unlockable passive item added in The Binding of Isaac: Afterbirth † (Booster Pack #2).
Effects
- Upon taking damage, Isaac gains a body part as an orbital, which blocks enemy shots and deals 7 damage per tick (35 damage per second) to enemies it comes in contact with.
- A maximum of three body parts can be active at once.
- The body parts will be destroyed after dealing 30 ticks of damage and/or blocking 3 shots.
- The body parts persist between floors.
- Body parts orbit on the same layer as Blue Flies and Locusts do.
Interactions
Box of Friends: Will not multiply orbitals.
In-game Footage
Trivia
- The description "You're tearing me apart!" is a reference to the movie The Room (which Edmund has said he is a big fan of), in which Tommy Wiseau famously exclaims "You're tearing me apart, Lisa!".
- Leprosy was inspired by a Steam Workshop item by Bobby Lashley Fangirl #1.
- The item used to be misspelled "Leprocy" but was corrected in a later patch.
- The item is a reference to leprosy, a bacterial disease that damages nerves and can cause extremities to rot in extreme cases.
Gallery
- The Forgotten has a unique appearance with Leprosy, making him look visually similar to Melting, a playable character from the game Nuclear Throne.
 The Binding of Isaac: Rebirth
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