Binding of Isaac: Rebirth Wiki
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Monsters refers to the many antagonistic creatures the player will encounter throughout the game.

Most monsters (with few exceptions) will damage Isaac by either touching him or shooting him with projectiles. Less frequently, monsters will spawn additional, lesser monsters, spread creep, or attempt to affect the player's movement. Along with the more common variety of monsters, champion versions can be found lurking about. These monsters are often like their common counterparts, but have a color tint or size change and drop basic pickups on death. There are also champion versions of most bosses.

There are 197 monsters in total. 39 of them were added in Afterbirth (Ultra Greed Coins counted) and 20 were added in Afterbirth † (12 were added in Booster Packs).

Monster List

Champions

Some monsters can spawn as a Champion which deviates in coloration and size from its more common form. The champion's coloration denotes which peculiar behaviors and traits it will exhibit. Champions will generally drop a pickup (coinciding with the color of the champion) when killed on normal difficulty. However, in hard mode, fewer champions will drop pickups on death. Most champions inflict full heart damage regardless of chapter and have double the health of a normal monster. The likelihood of champions appearing is increased by unlocking the Everything Is Terrible! achievement, by carrying the Purple Heart trinket, by picking up the Champion Belt item, or by playing in hard mode. Champions are generally regarded as more dangerous than common monsters. (in Rebirth and Afterbirth) In addition, all champions will deal contact damage, regardless of what monster they are (e.g. a common Mulligan will not deal contact damage, but champion versions will).

The identifying scheme for champion qualities is as follows:

ID Appearance Effect Drop
0 Champion Red
Red
×2.5 amount of HP. Heart
1 Champion Yellow
Yellow
Increased movement and shot speed. Little battery
2 Champion Green
Green
Leaves green creep as it walks. Pill
3 Champion Orange
Orange
Attacks cause you to drop coins (like Greed or a Hanger). Coin
4 Champion Dark Blue
Dark Blue
None. 3 blue flies
5 Champion Dark Green
Dark Green
Explodes when killed. Bomb
6 Champion Solid White
Solid White
Invincible until all other enemies are killed. Eternal Heart
7 Champion Gray
Gray
Has 2/3 health, but deals double damage. Key
8 Champion Transparent White
Transparent White
Tears become spectral tears, and it can move past environmental obstacles (such as pits) that it otherwise couldn't when forced. Golden Chest
9 Champion Black
Black
Fades in and out of visibility, like a Null. Red Chest
10 Champion Pink
Pink
Periodically shoots short-ranged blood shots, similar to Gushers. Nothing
11 Champion Purple
Purple
Pulls Isaac towards itself, like a Gaping Maw. random Trinket
12 Champion Dark Red
Dark Red
Collapses into a flesh pile upon death and regenerates if not finished off (like a Globin). 1+1 Free Heart
13 Champion Light Blue
Light Blue
Releases blood shots in 8 directions when killed. 1/2 heart
14 Champion Camouflage
(except in Rebirth) Camouflage
The enemy blends into the background and briefly becomes visible when damaged. Rune
15 Champion Pulsing Green
(except in Rebirth) Pulsing Green
Splits into two copies of itself upon death. 2 normal versions of itself
16 Champion Pulsing Gray
(except in Rebirth) Pulsing Gray
Repels Isaac's shots when it pulses. Nothing
17 Champion Light White
(except in Rebirth) Light White
Has 1-2 eternal flies circling it. Spawns another fly upon death. Attack Fly
18 Gaper
(except in Rebirth) Small
Decreased health, increased speed and increases the pitch of its voice. Smaller and more difficult to hit. One Makes You Small pill
19 Gaper
(except in Rebirth) Large
Increased health, decreased speed and decreases the pitch of its voice. Larger and easier to hit. Deals two full hearts of damage. One Makes You Larger pill
20 Champion Pulsing Red
(in Afterbirth † and Repentance) Pulsing Red
All other enemies in the room regenerate health rapidly while this enemy is alive. Heart
21 Champion Pulsating
(in Afterbirth † and Repentance) Pulsating
Spawns an Attack Fly per hit. 5 blue flies
22 Champion Crown
(in Afterbirth † and Repentance) Crown
Increased health. All enemies in the room that are not champions will turn into yellow champions while the crowned enemy is alive. 2 random pickups
23 Champion Skull
(in Afterbirth † and Repentance) Skull
Produces a Necronomicon effect upon death. Deals two full hearts of damage. Necronomicon effect

Monster Variants

These uncommon variants may replace common enemies in a room. (Note: Some variants of enemies may not replace other enemies depending on the environment and chapter the player is in.)

Rebirth

Base Monster Possible Replacements
Mulligan Mulligoon or Mulliboom
Mulligoon Mulliboom
Hopper Trite
Stone Grimace Vomit Grimace
Dople Evil Twin
Eye Bloodshot Eye
Leech Kamikaze Leech or Holy Leech
Maw Red Maw or Psychic Maw
Red Maw Psychic Maw
Host Red Host
Vis Double Vis or Chubber
Boom Fly Red Boom Fly
Pooter Fat Fly
Knight Selfless Knight
Clotty or Clot I.Blob
MemBrain Mama Guts
Globin Gazing Globin
Baby Angelic Baby
Boil Sack or Gut
Gut Sack
Sucker Spit
Poky Slide

Afterbirth

Base Monster Possible Replacements
Frowning Gaper or Gaper Flaming Gaper (Burning Basement Only)
Fatty or Pale Fatty Flaming Fatty (Burning Basement Only)
Hopper Flaming Hopper (Burning Basement Only)
Hive Drowned Hive (Flooded Caves Only)
Maggot or Charger or Spitty Drowned Charger (Flooded Caves Only)
Boom Fly or Red Boom Fly Drowned Boom Fly (Flooded Caves Only)
Squirt Dank Squirt (Dank Depths Only)
Death's Head Dank Death's Head (Dank Depths Only)
Globin or Gazing Globin Dank Globin (Dank Depths Only)
Guts Scarred Guts (Scarred Womb Only)
Para-Bite Scarred Para-Bite (Scarred Womb Only)
Vis or Double Vis Scarred Double Vis (Scarred Womb Only)

Afterbirth †

Base Monster Possible Replacements
Keeper or Ticking Spider Blister
Host or Red Host Mushroom (Enemy)
Hopper or Trite Ministro
Nerve Ending Nerve Ending 2
Brain Poison Mind
Pale Fatty Stoney
Wall Creep or Blind Creep or Rage Creep The Thing
Mr Maw Mr. Red Maw
Skinny Crispy (Burning Basement only)
Stoney Cross Stoney (Aprils Fool challenge only)


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