My Little Unicorn is an activated item.
Effects
- Upon use, grants invulnerability and increased speed for six seconds, removing the ability to shoot tears and replacing it with the ability to deal 40 contact damage to enemies.
- Damage is dealt once per second per enemy.
Notes
- The invulnerability effect negates all forms of damage, including health loss from Blood Donation Machines and Devil Beggars.
- Does not prevent heart container loss from Health Down Pills or Devil Room deals.
- Ending the current run via opening the end chest while My Little Unicorn is active will cause the credits and main menu music to be sped up. The effect ends upon restarting the game or starting a new run.
- The Chariot card provides the effect of this item when used.
In-game Footage
Gallery
3DS The icon of My Little Unicorn as seen on the lower 3DS screen
Trivia
- The item is a reference to the show My Little Pony.
- In the original Binding Of Isaac, using the item changed the music instead of speeding it up.
Seeds
PC NYMW 989S (First floor adjacent Treasure Room)
PC 7EJT ZNWN (Treasure room in Basement I)
3DS XYCH AG1D (Treasure room adjacent to spawn)
PC 
FWSH R8CF (Treasure room adjacent to spawn) (Hard mode only)
PC FSMV XLCZ (Treasure room adjacent to spawn) (Both modes)
 Bones
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| Trinkets |
 The Binding of Isaac: Rebirth
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